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	<title>English Abstract &#8211; Cyprus Society of Human Genetics (CSHG)</title>
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	<description>Cyprus Society of Human Genetics (CSHG)</description>
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	<title>English Abstract &#8211; Cyprus Society of Human Genetics (CSHG)</title>
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		<title>[A new species of wild mice on the Island of Cyprus].</title>
		<link>https://cshg.org.cy/a-new-species-of-wild-mice-on-the-island-of-cyprus/</link>
		
		<dc:creator><![CDATA[istotopos]]></dc:creator>
		<pubDate>Tue, 21 Aug 2018 13:44:58 +0000</pubDate>
				<category><![CDATA[English Abstract]]></category>
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					<description><![CDATA[Abstract A mitochondrial and nuclear gene analysis allowed us to precise the taxonomical position of the two sympatric species of mice known to be present on Cyprus. One of them [&#8230;]]]></description>
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<p><b>Abstract</b><br />
A mitochondrial and nuclear gene analysis allowed us to precise the taxonomical position of the two sympatric species of mice known to be present on Cyprus. One of them is the commensal house mouse M. m. domesticus, and the other revealed to be a new taxon that is a sister species of M. spicilegus and M. macedonicus. The new species is equidistant from each of these, the divergence dating around 0.5-1 Myr. Its origin either results from an ancient accidental colonisation of the island or from a recent transportation by the first epipalaeolithic settlers. In this last eventuality, the new species would also exist somewhere else in Asia Minor.</p>
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		<title>[An epidemiological study on canine leishmaniasis (CanL) and sand flies in Northern Cyprus].</title>
		<link>https://cshg.org.cy/an-epidemiological-study-on-canine-leishmaniasis-canl-and-sand-flies-in-northern-cyprus/</link>
		
		<dc:creator><![CDATA[istotopos]]></dc:creator>
		<pubDate>Tue, 21 Aug 2018 13:41:41 +0000</pubDate>
				<category><![CDATA[English Abstract]]></category>
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					<description><![CDATA[Abstract In this study, the investigation on the prevalence of canine leishmaniasis (CanL) and sand fly species incriminated as potential vectors of leishmaniasis in the northern part of the Cyprus [&#8230;]]]></description>
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<p><b>Abstract</b><br />
In this study, the investigation on the prevalence of canine leishmaniasis (CanL) and sand fly species incriminated as potential vectors of leishmaniasis in the northern part of the Cyprus were aimed.</p>
<p>This research was conducted in two periods; 2004 and 2012. Serological (IFAT and rK39) and molecular (PCR) tests were performed on 83 dog blood samples during the 2004 survey. PCR was performed using primers 13A/13B targeting kinetoplastid minicircle constant region. Genomic Nested-PCR was applied using R221/R332 and R323/333 primers for 5 clinically suspected dog samples in 2012. Sand flies were collected from the Lapithos town and Kyreniae province using CDC light traps and midgut dissection was done for the presence of Leishmania parasites during the 2012 survey.<br />
Three (3.61%) out of 83 dogs were found to be positive for CanL in 2004, while 3 out of 5 clinically suspected dogs were positive in 2012. In total 296 female sand flies were dissected and 9 species belonging to Phlebotomus and Sergentomyia genera were determined. No promastigote was found in the dissected females.</p>
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		<title>[Molecular epidemiology of hepatitis B virus in Northern Cyprus].</title>
		<link>https://cshg.org.cy/molecular-epidemiology-of-hepatitis-b-virus-in-northern-cyprus/</link>
		
		<dc:creator><![CDATA[istotopos]]></dc:creator>
		<pubDate>Tue, 21 Aug 2018 13:38:41 +0000</pubDate>
				<category><![CDATA[English Abstract]]></category>
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					<description><![CDATA[Abstract Identification of hepatitis B virus (HBV) strains and understanding of molecular epidemiological characteristics are important for the effective surveillance of HBV infections. Genotype D is dominant in studies performed [&#8230;]]]></description>
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<p><b>Abstract</b><br />
Identification of hepatitis B virus (HBV) strains and understanding of molecular epidemiological characteristics are important for the effective surveillance of HBV infections. Genotype D is dominant in studies performed in Turkey but it is known that cases infected with genotypes A, E, G and H also exists. In contrast, there are no data regarding the molecular epidemiologic characteristics of the HBV in Northern Cyprus. The aim of this study was to determine the distribution of genotypes and subgenotypes of HBV among the people living, educating and working in Northern Cyprus. A total of 160 cases (1.2%) who were HBsAg seropositive out of 13.892 subjects admitted to Nicosia, Near East University Hospital microbiology laboratory for the routine control and to blood center for donor screening tests between November 2011 to September 2014, were included in the study. HBV-DNA levels in the HBsAg positive cases were detected by real-time polymerase chain reaction and genotypes/subgenotypes were determined by sequence analysis of the viral pol gene (reverse transcriptase [rt] region, between 80-250. aminoacids). Sixty samples (60/160, 37.5%) were excluded from sequencing analysis due to negative and/or very low (&lt; 30 IU/ml) HBV-DNA levels, so 100 samples were included in sequence analysis. Ninety-six of those cases (13 female, 87 male; mean age: 35.51 ± 12.88 years) were anti-HBc IgG, 95 were anti-HBe and five were HBeAg positive, with a mean HBV-DNA level of 5.36 x 10(6) ± 3.58 x 10(7) IU/ml. As 32 (32%) samples yielded HBV-DNA level below the threshold of 1000 IU/ml, sequence analyses were unsuccesful, eventually 68 (68/160, 42.5%) samples could be phylogenetically analyzed. The distribution of HBV genotypes/subgenotypes were found as follows: 48 were (70.6%) D/D1; four were (5.9%) D/D2; one was (1.5%) D/D3, five were (7.4%) A/A1, two were (2.9%) A/A2 and eight were (11.8%) genotype E. Among the most frequent D1 strains, 60.4% (29/48) cases were from Turkish; single D/D3 strain from Benguela (Angola) and all eight genotype E strains were from Nigerian national cases. According to the data of this first study performed in TRNC on this subject, genotype D is dominant (53/68, 78%) in Northern Cyprus and consistent with the subgenotype distribution that is similar to Turkey and mediterranean basin. The prevalences of genotype A (7/68, 10.3%) and E (8/68, 11.8%) were also remarkable. In conclusion, although Northern Cyprus is an island country the heterogeneous distribution of HBV genotype/subgenotype may be contributed to the cosmopolitan characteristics of various populations from different countries who have come here for education, work or touristic purposes.</p>
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