Read more about the article FRAXA and FRAXE prevalence in patients with nonspecific mental retardation in the Hellenic population.
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FRAXA and FRAXE prevalence in patients with nonspecific mental retardation in the Hellenic population.

Abstract Mutations at FRAXA and FRAXE loci are due to expansions of a CGG trinucleotide repeat and are characterized by mental retardation. Here we report a pilot screening survey by…

Continue ReadingFRAXA and FRAXE prevalence in patients with nonspecific mental retardation in the Hellenic population.
Read more about the article Neurogenic vestibular evoked potentials in the diagnosis of multiple sclerosis.
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Neurogenic vestibular evoked potentials in the diagnosis of multiple sclerosis.

Abstract To determine the value of neurogenic vesibular evoked potential (NVESTEP) studies in comparison with other paraclinical tests in demonstrating dissemination in time and space in Multiple Sclerosis (MS) and…

Continue ReadingNeurogenic vestibular evoked potentials in the diagnosis of multiple sclerosis.
Read more about the article Intermittent chemotherapy plus either intermittent or continuous cetuximab for first-line treatment of patients with KRAS wild-type advanced colorectal cancer (COIN-B): a randomised phase 2 trial.
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Intermittent chemotherapy plus either intermittent or continuous cetuximab for first-line treatment of patients with KRAS wild-type advanced colorectal cancer (COIN-B): a randomised phase 2 trial.

Abstract Advanced colorectal cancer is treated with a combination of cytotoxic drugs and targeted treatments. However, how best to minimise the time spent taking cytotoxic drugs and whether molecular selection…

Continue ReadingIntermittent chemotherapy plus either intermittent or continuous cetuximab for first-line treatment of patients with KRAS wild-type advanced colorectal cancer (COIN-B): a randomised phase 2 trial.
Read more about the article Evidence for contribution of the y chromosome in atherosclerotic plaque occurrence in men.
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Evidence for contribution of the y chromosome in atherosclerotic plaque occurrence in men.

Abstract Diseases such as atherosclerosis and coronary artery disease demonstrate disparate population prevalence or present with variable severity in men and women. While the usual explanation points to hormonal status,…

Continue ReadingEvidence for contribution of the y chromosome in atherosclerotic plaque occurrence in men.
Read more about the article Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.
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Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.

Abstract The diagnosis of hematologic malignancies relies on multidisciplinary workflows involving morphology, flow cytometry, cytogenetic, and molecular genetic analyses. Advances in cancer genomics have identified numerous recurrent mutations with clear…

Continue ReadingDevelopment and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.
Read more about the article The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.
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The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.

Abstract Ninety-four common genetic variants are confirmed to be associated with breast cancer. This study tested the hypothesis that breast cancer susceptibility variants may also be associated with chemotherapy-induced toxicity…

Continue ReadingThe Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.
Read more about the article Nipple aspirate fluid-A liquid biopsy for diagnosing breast health.
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Nipple aspirate fluid-A liquid biopsy for diagnosing breast health.

Abstract Nipple secretions are protein-rich and a potential source of breast cancer biomarkers for breast cancer screening. Previous studies of specific proteins have shown limited correlation with clinicopathological features. Our…

Continue ReadingNipple aspirate fluid-A liquid biopsy for diagnosing breast health.