Read more about the article The care of adolescents and young adults with cancer: results of the ESMO/SIOPE survey.
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The care of adolescents and young adults with cancer: results of the ESMO/SIOPE survey.

Abstract Adolescents and young adults (AYA) with cancer require dedicated clinical management and care. Little is known about the training and practice of European healthcare providers in regard to AYA…

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Read more about the article Targeting Histone Deacetylases in Malignant Melanoma: A Future Therapeutic Agent or Just Great Expectations?
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Targeting Histone Deacetylases in Malignant Melanoma: A Future Therapeutic Agent or Just Great Expectations?

Abstract Malignant melanoma is the most aggressive type of skin cancer, with increasing frequency and mortality. Melanoma is characterized by rapid proliferation and metastases. Malignant transformation of normal melanocytes is…

Continue ReadingTargeting Histone Deacetylases in Malignant Melanoma: A Future Therapeutic Agent or Just Great Expectations?
Read more about the article Digenic inheritance and genetic modifiers.
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Digenic inheritance and genetic modifiers.

Abstract Digenic inheritance (DI) concerns pathologies with the simplest form of multigenic etiology, implicating more than 1 gene (and perhaps the environment). True DI is when biallelic or even triallelic…

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Read more about the article Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.
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Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.

Abstract Idiopathic Pulmonary Fibrosis (IPF) is a rare disease of the respiratory system in which the lungs stiffen and get scarred, resulting in breathing weakness and eventually leading to death.…

Continue ReadingDrug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.
Read more about the article Restless legs syndrome in adolescents: relationship with sleep quality, cardiorespiratory fitness and body fat.
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Restless legs syndrome in adolescents: relationship with sleep quality, cardiorespiratory fitness and body fat.

Abstract The aim of the current study was to investigate the relationship between restless legs syndrome (RLS) and cardiorespiratory fitness, body composition and sleep quality in a sample of adolescents.…

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Read more about the article Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.
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Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.

Abstract Pediatric cancer survivors are a steadily growing population; however, chronic anthracycline-induced cardiotoxicity (AIC) is a serious long-term complication leading to considerable morbidity. We aimed to identify new genes and…

Continue ReadingExome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.
Read more about the article Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy.
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Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy.

Abstract Penetrance and age of onset of ATTRV30M amyloidotic neuropathy varies significantly among different populations. This variability has been attributed to both genetic and environmental modifiers. We studied the effect…

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Read more about the article Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients.
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Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients.

Abstract To examine whether hemodialysis (HD) patients with restless legs syndrome (RLS) are subjects of greater fatigue and impaired quality of life (QoL) compared to HD patients without RLS. Eighty…

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Read more about the article Comparative effect of imatinib and ponatinib on autophagy and miRNome in chronic myeloid leukemia.
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Comparative effect of imatinib and ponatinib on autophagy and miRNome in chronic myeloid leukemia.

Abstract BCR-ABL tyrosine kinase inhibitors (TKIs) are selective therapies for the patients with Chronic Myeloid Leukemia (CML). Imatinib and ponatinib have remarkable long-term efficacy on a major molecular response. Although…

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Read more about the article The Reply.
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