Read more about the article Molecular comparisons of the Culex pipiens (L.) complex esterase gene amplicons.
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Molecular comparisons of the Culex pipiens (L.) complex esterase gene amplicons.

Abstract The amplification of carboxylesterase genes is a mechanism of organophosphate resistance in Culex mosquitoes. Amplified carboxylesterase genes from an insecticide resistant Culex pipiens strain collected in Cyprus were analysed…

Continue ReadingMolecular comparisons of the Culex pipiens (L.) complex esterase gene amplicons.
Read more about the article Repair of myotonic dystrophy protein kinase (DMPK) transcripts by trans-splicing ribozymes.
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Repair of myotonic dystrophy protein kinase (DMPK) transcripts by trans-splicing ribozymes.

Abstract The Tetrahymena group I intron ribozyme is an RNA molecule of approx 400 bases that is capable of base-specific RNA trans-splicing. These properties can be applied to repair mutations…

Continue ReadingRepair of myotonic dystrophy protein kinase (DMPK) transcripts by trans-splicing ribozymes.
Read more about the article Th2/Th3 cytokine genotypes are associated with pregnancy loss.
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Th2/Th3 cytokine genotypes are associated with pregnancy loss.

Abstract Cytokines are critical immunoregulatory molecules, responsible for determining the nature of an immune response. It has been proposed that Th2/Th3 immune reactions support normal pregnancy, while Th1 immunity is…

Continue ReadingTh2/Th3 cytokine genotypes are associated with pregnancy loss.
Read more about the article Genetic assessment of cardiovascular risk factors in the Greek Cypriot population.
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Genetic assessment of cardiovascular risk factors in the Greek Cypriot population.

Abstract

Continue ReadingGenetic assessment of cardiovascular risk factors in the Greek Cypriot population.
Read more about the article A comparative morphological study in 33 cases of respiratory chain encephalomyopathies.
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A comparative morphological study in 33 cases of respiratory chain encephalomyopathies.

Abstract Mitochondrial encephalomyopathies (ME) are clinically and genetically heterogeneous syndromes ranging from pure myopathies to complex multisystem disorders. This phenotypic and genotypic variability, coupled with the lack of a laboratory…

Continue ReadingA comparative morphological study in 33 cases of respiratory chain encephalomyopathies.
Read more about the article Preimplantation HLA typing and stem cell transplantation: report of International Meeting, Cyprus, 27-8 March, 2004.
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Preimplantation HLA typing and stem cell transplantation: report of International Meeting, Cyprus, 27-8 March, 2004.

Abstract There has been progress in the application of stem cell transplantation for the treatment of an increasing number of severe congenital and acquired bone marrow disorders that are currently…

Continue ReadingPreimplantation HLA typing and stem cell transplantation: report of International Meeting, Cyprus, 27-8 March, 2004.
Read more about the article Description of the first two seemingly unrelated Greek Cypriot families with a common C618R RET proto-oncogene mutation.
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Description of the first two seemingly unrelated Greek Cypriot families with a common C618R RET proto-oncogene mutation.

Abstract Germ-line mutations of the RET proto-oncogene cause three different cancer syndromes: multiple endocrine neoplasia type 2A (MEN2A), multiple endocrine neoplasia type 2B, and familial medullary thyroid carcinoma (FMTC). The…

Continue ReadingDescription of the first two seemingly unrelated Greek Cypriot families with a common C618R RET proto-oncogene mutation.
Read more about the article Restoration of protein synthesis in pancreatic cancer cells by trans-splicing ribozymes.
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Restoration of protein synthesis in pancreatic cancer cells by trans-splicing ribozymes.

Abstract This report describes the use of trans-splicing ribozymes to restore p16 protein synthesis in pancreatic cancer cells. A group I intron ribozyme was designed to trans-splice the 2 base-deleted…

Continue ReadingRestoration of protein synthesis in pancreatic cancer cells by trans-splicing ribozymes.
Read more about the article Distribution and functions of kinectin isoforms.
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Distribution and functions of kinectin isoforms.

Abstract Kinectin is an integral transmembrane protein on the endoplasmic reticulum, binding to kinesin, interacting with Rho GTPase and anchoring the translation elongation factor-1 complex. There has been debate on…

Continue ReadingDistribution and functions of kinectin isoforms.
Read more about the article Choosing eugenics: how far will nations go to eliminate a genetic disease?
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Choosing eugenics: how far will nations go to eliminate a genetic disease?

Abstract

Continue ReadingChoosing eugenics: how far will nations go to eliminate a genetic disease?