Read more about the article Circulation of enteroviruses in Cyprus assessed by molecular analysis of clinical specimens and sewage isolates.
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Circulation of enteroviruses in Cyprus assessed by molecular analysis of clinical specimens and sewage isolates.

Abstract To study the circulation of non-polio enteroviruses in the Cypriot population and assess the clinical relevance of different serotypes by the analysis of clinical specimens and environmental samples. Sewage…

Continue ReadingCirculation of enteroviruses in Cyprus assessed by molecular analysis of clinical specimens and sewage isolates.
Read more about the article Computational protein design with a generalized Born solvent model: application to Asparaginyl-tRNA synthetase.
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Computational protein design with a generalized Born solvent model: application to Asparaginyl-tRNA synthetase.

Abstract Computational Protein Design (CPD) is a promising method for high throughput protein and ligand mutagenesis. Recently, we developed a CPD method that used a polar-hydrogen energy function for protein…

Continue ReadingComputational protein design with a generalized Born solvent model: application to Asparaginyl-tRNA synthetase.
Read more about the article Increased number of microRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction.
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Increased number of microRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction.

Abstract MicroRNAs (miRNAs) and copy number variations (CNVs) are two newly discovered genetic elements that have revolutionized the field of molecular biology and genetics. By performing in silico whole genome…

Continue ReadingIncreased number of microRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction.
Read more about the article Systematics and evolution of Arctic-Alpine Arabis alpina (Brassicaceae) and its closest relatives in the eastern Mediterranean.
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Systematics and evolution of Arctic-Alpine Arabis alpina (Brassicaceae) and its closest relatives in the eastern Mediterranean.

Abstract The high mountains in southern Anatolia and the eastern Mediterranean are assumed to play a major role as a primary center of genetic diversity and species richness in Eurasia.…

Continue ReadingSystematics and evolution of Arctic-Alpine Arabis alpina (Brassicaceae) and its closest relatives in the eastern Mediterranean.
Read more about the article Microsatellite markers within the α-globin gene cluster for robust preimplantation genetic diagnosis of severe α-thalassemia syndromes in Mediterranean populations.
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Microsatellite markers within the α-globin gene cluster for robust preimplantation genetic diagnosis of severe α-thalassemia syndromes in Mediterranean populations.

Abstract In this study we report the development of a generic protocol for preimplantation genetic diagnosis (PGD) of severe α-thalassemia (α-thal) syndromes in α-thal carrier couples of Mediterranean origin. The…

Continue ReadingMicrosatellite markers within the α-globin gene cluster for robust preimplantation genetic diagnosis of severe α-thalassemia syndromes in Mediterranean populations.
Read more about the article Duplication of exons 3-10 of the HSD17B3 gene: a novel type of genetic defect underlying 17β-HSD-3 deficiency.
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Duplication of exons 3-10 of the HSD17B3 gene: a novel type of genetic defect underlying 17β-HSD-3 deficiency.

Abstract The clinical, biochemical and genetic features of a Cypriot origin male of non-consanguineous parents due to 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD-3) deficiency are presented. The patient, currently a 10…

Continue ReadingDuplication of exons 3-10 of the HSD17B3 gene: a novel type of genetic defect underlying 17β-HSD-3 deficiency.
Read more about the article The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study.
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The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study.

Abstract Diet has long been suspected to impact on breast cancer risk. In this study we evaluated whether the degree of adherence to a Mediterranean diet pattern modifies breast cancer…

Continue ReadingThe mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study.
Read more about the article Identification and characterization of a novel X-linked AVPR2 mutation causing partial nephrogenic diabetes insipidus: a case report and review of the literature.
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Identification and characterization of a novel X-linked AVPR2 mutation causing partial nephrogenic diabetes insipidus: a case report and review of the literature.

Abstract X-linked nephrogenic diabetes insipidus (NDI) is a rare disease characterized by a malfunctioning renal response to the antidiuretic hormone arginine vasopressin (AVP) due to mutations in the AVPR2 gene.…

Continue ReadingIdentification and characterization of a novel X-linked AVPR2 mutation causing partial nephrogenic diabetes insipidus: a case report and review of the literature.
Read more about the article Autoimmune channelopathies of the nervous system.
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Autoimmune channelopathies of the nervous system.

Abstract Ion channels are complex transmembrane proteins that orchestrate the electrical signals necessary for normal function of excitable tissues, including the central nervous system, peripheral nerve, and both skeletal and…

Continue ReadingAutoimmune channelopathies of the nervous system.
Read more about the article Multilocus microsatellite typing (MLMT) of strains from Turkey and Cyprus reveals a novel monophyletic L. donovani sensu lato group.
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Multilocus microsatellite typing (MLMT) of strains from Turkey and Cyprus reveals a novel monophyletic L. donovani sensu lato group.

Abstract New foci of human CL caused by strains of the Leishmania donovani (L. donovani) complex have been recently described in Cyprus and the Çukurova region in Turkey (L. infantum)…

Continue ReadingMultilocus microsatellite typing (MLMT) of strains from Turkey and Cyprus reveals a novel monophyletic L. donovani sensu lato group.