Read more about the article Molecular epidemiology of rhinoviruses in Cyprus over three consecutive seasons.
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Molecular epidemiology of rhinoviruses in Cyprus over three consecutive seasons.

Abstract Human rhinoviruses (HRVs) are widespread respiratory pathogens and a major cause of acute respiratory tract infections. The aim of this study was to investigate the molecular epidemiology of rhinovirus…

Continue ReadingMolecular epidemiology of rhinoviruses in Cyprus over three consecutive seasons.
Read more about the article Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol.
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Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol.

Abstract Prognostic stratification is critical for making therapeutic decisions and maximizing survival of patients with acute myeloid leukemia. Advances in the genomics of acute myeloid leukemia have identified several recurrent…

Continue ReadingCharacterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol.
Read more about the article Prevalence of overweight and obesity in European children below the age of 10.
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Prevalence of overweight and obesity in European children below the age of 10.

Abstract There is a lack of common surveillance systems providing comparable figures and temporal trends of the prevalence of overweight (OW), obesity and related risk factors among European preschool and…

Continue ReadingPrevalence of overweight and obesity in European children below the age of 10.
Read more about the article Status epilepticus developing during lacosamide monotherapy.
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Status epilepticus developing during lacosamide monotherapy.

Abstract Two cases with partial onset epilepsy who developed status epilepticus (SE) on lacosamide (LCM) monotherapy are reported. LCM is an effective adjunctive antiepileptic drug (AED) for partial-onset epilepsy and…

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Read more about the article Intestinal microbiota and diet in IBS: causes, consequences, or epiphenomena?
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Intestinal microbiota and diet in IBS: causes, consequences, or epiphenomena?

Abstract Irritable bowel syndrome (IBS) is a heterogeneous functional disorder with a multifactorial etiology that involves the interplay of both host and environmental factors. Among environmental factors relevant for IBS…

Continue ReadingIntestinal microbiota and diet in IBS: causes, consequences, or epiphenomena?
Read more about the article Developmental determinants in non-communicable chronic diseases and ageing.
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Developmental determinants in non-communicable chronic diseases and ageing.

Abstract Prenatal and peri-natal events play a fundamental role in health, development of diseases and ageing (Developmental Origins of Health and Disease (DOHaD)). Research on the determinants of active and…

Continue ReadingDevelopmental determinants in non-communicable chronic diseases and ageing.
Read more about the article The first family with Tay-Sachs disease in Cyprus: Genetic analysis reveals a nonsense (c.78G>A) and a silent (c.1305C>T) mutation and allows preimplantation genetic diagnosis.
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The first family with Tay-Sachs disease in Cyprus: Genetic analysis reveals a nonsense (c.78G>A) and a silent (c.1305C>T) mutation and allows preimplantation genetic diagnosis.

Abstract Tay-Sachs disease (TSD) is a recessively inherited neurodegenerative disorder caused by mutations in the HEXA gene resulting in β-hexosaminidase A (HEX A) deficiency and neuronal accumulation of GM2 ganglioside.…

Continue ReadingThe first family with Tay-Sachs disease in Cyprus: Genetic analysis reveals a nonsense (c.78G>A) and a silent (c.1305C>T) mutation and allows preimplantation genetic diagnosis.
Read more about the article Single-nucleotide polymorphisms in one-carbon metabolism genes, Mediterranean diet and breast cancer risk: a case-control study in the Greek-Cypriot female population.
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Single-nucleotide polymorphisms in one-carbon metabolism genes, Mediterranean diet and breast cancer risk: a case-control study in the Greek-Cypriot female population.

Abstract Single-nucleotide polymorphisms (SNPs) within genes of the one-carbon metabolism pathway have been shown to interact with dietary folate intake to modify breast cancer (BC) risk. Our group has previously…

Continue ReadingSingle-nucleotide polymorphisms in one-carbon metabolism genes, Mediterranean diet and breast cancer risk: a case-control study in the Greek-Cypriot female population.
Read more about the article Number of embryos biopsied as a predictive indicator for the outcome of preimplantation genetic diagnosis by fluorescence in situ hybridisation in translocation cases.
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Number of embryos biopsied as a predictive indicator for the outcome of preimplantation genetic diagnosis by fluorescence in situ hybridisation in translocation cases.

Abstract This study aimed to investigate the optimum number of embryos to be biopsied in order to increase the likelihood of obtaining a balanced/normal embryo following preimplantation genetic diagnosis (PGD)…

Continue ReadingNumber of embryos biopsied as a predictive indicator for the outcome of preimplantation genetic diagnosis by fluorescence in situ hybridisation in translocation cases.
Read more about the article Altered metabolic pathways in clear cell renal cell carcinoma: A meta-analysis and validation study focused on the deregulated genes and their associated networks.
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Altered metabolic pathways in clear cell renal cell carcinoma: A meta-analysis and validation study focused on the deregulated genes and their associated networks.

Abstract Clear cell renal cell carcinoma (ccRCC) is the predominant subtype of renal cell carcinoma (RCC). It is one of the most therapy-resistant carcinomas, responding very poorly or not at…

Continue ReadingAltered metabolic pathways in clear cell renal cell carcinoma: A meta-analysis and validation study focused on the deregulated genes and their associated networks.