Read more about the article Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.
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Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.

Abstract Two tetrapeptides, HAEE and RADD, which are ionic-complementary to the primary zinc recognition site of amyloid-β (Aβ), have been reported to inhibit zinc-induced dimerization of the Aβ metal-binding domain…

Continue ReadingPeripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.
Read more about the article Evolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.
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Evolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.

Abstract Human hGDH2 arose via duplication in the apes and driven by positive selection acquired enhanced catalytic ability under conditions inhibitory to its precursor hGDH1 (common to all mammals). To…

Continue ReadingEvolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.
Read more about the article A rare cause of pruritic ichthyosis: Sjögren-Larsson syndrome in the first reported patients of Cypriot descent.
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A rare cause of pruritic ichthyosis: Sjögren-Larsson syndrome in the first reported patients of Cypriot descent.

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Abstract

Continue ReadingA rare cause of pruritic ichthyosis: Sjögren-Larsson syndrome in the first reported patients of Cypriot descent.
Read more about the article Effect of the IDEFICS multilevel obesity prevention on children’s sleep duration.
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Effect of the IDEFICS multilevel obesity prevention on children’s sleep duration.

Abstract According to recent findings, short sleep duration is associated with overweight in children. However, primary prevention efforts aimed at achieving adequate sleep among children are scarce. Therefore, the 'Identification…

Continue ReadingEffect of the IDEFICS multilevel obesity prevention on children’s sleep duration.
Read more about the article Effectiveness of the IDEFICS intervention on objectively measured physical activity and sedentary time in European children.
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Effectiveness of the IDEFICS intervention on objectively measured physical activity and sedentary time in European children.

Abstract This paper reports on the effectiveness of the prevention of dietary- and lifestyle-induced health effects in children and infants (IDEFICS) intervention on objectively measured physical activity (PA) and sedentary…

Continue ReadingEffectiveness of the IDEFICS intervention on objectively measured physical activity and sedentary time in European children.
Read more about the article Impact of a community based health-promotion programme in 2- to 9-year-old children in Europe on markers of the metabolic syndrome, the IDEFICS study.
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Impact of a community based health-promotion programme in 2- to 9-year-old children in Europe on markers of the metabolic syndrome, the IDEFICS study.

Abstract One objective of 'Identification and prevention of Dietary-and lifestyle-induced health EFfects In Children and infantS', the IDEFICS study, was to implement a community-oriented childhood obesity prevention intervention in eight…

Continue ReadingImpact of a community based health-promotion programme in 2- to 9-year-old children in Europe on markers of the metabolic syndrome, the IDEFICS study.
Read more about the article Effects of a community-oriented obesity prevention programme on indicators of body fatness in preschool and primary school children. Main results from the IDEFICS study.
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Effects of a community-oriented obesity prevention programme on indicators of body fatness in preschool and primary school children. Main results from the IDEFICS study.

Abstract Childhood obesity is a major public health concern but evidence-based approaches to tackle this epidemic sustainably are still lacking. The Identification and prevention of Dietary- and lifestyle-induced health EFfects…

Continue ReadingEffects of a community-oriented obesity prevention programme on indicators of body fatness in preschool and primary school children. Main results from the IDEFICS study.
Read more about the article iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function.
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iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function.

Abstract SAFB1 is a RNA binding protein implicated in the regulation of multiple cellular processes such as the regulation of transcription, stress response, DNA repair and RNA processing. To gain…

Continue ReadingiCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function.
Read more about the article Genetic screening of EXT1 and EXT2 in Cypriot families with hereditary multiple osteochondromas.
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Genetic screening of EXT1 and EXT2 in Cypriot families with hereditary multiple osteochondromas.

Abstract

Continue ReadingGenetic screening of EXT1 and EXT2 in Cypriot families with hereditary multiple osteochondromas.
Read more about the article Dietary Carbohydrate and Nocturnal Sleep Duration in Relation to Children’s BMI: Findings from the IDEFICS Study in Eight European Countries.
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Dietary Carbohydrate and Nocturnal Sleep Duration in Relation to Children’s BMI: Findings from the IDEFICS Study in Eight European Countries.

Abstract Previous research has found an association between being overweight and short sleep duration. We hypothesized that this association could be modified by a high carbohydrate (HC) diet and that…

Continue ReadingDietary Carbohydrate and Nocturnal Sleep Duration in Relation to Children’s BMI: Findings from the IDEFICS Study in Eight European Countries.