Read more about the article Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.
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Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.

Abstract Two tetrapeptides, HAEE and RADD, which are ionic-complementary to the primary zinc recognition site of amyloid-β (Aβ), have been reported to inhibit zinc-induced dimerization of the Aβ metal-binding domain…

Continue ReadingPeripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.
Read more about the article Evolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.
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Evolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.

Abstract Human hGDH2 arose via duplication in the apes and driven by positive selection acquired enhanced catalytic ability under conditions inhibitory to its precursor hGDH1 (common to all mammals). To…

Continue ReadingEvolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.
Read more about the article A rare cause of pruritic ichthyosis: Sjögren-Larsson syndrome in the first reported patients of Cypriot descent.
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A rare cause of pruritic ichthyosis: Sjögren-Larsson syndrome in the first reported patients of Cypriot descent.

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Abstract

Continue ReadingA rare cause of pruritic ichthyosis: Sjögren-Larsson syndrome in the first reported patients of Cypriot descent.
Read more about the article Reprising the taxonomy of Cyprus Scops Owl Otus (scops) cyprius, a neglected island endemic.
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Reprising the taxonomy of Cyprus Scops Owl Otus (scops) cyprius, a neglected island endemic.

Abstract The endemic Cyprus Scops Owl Otus (scops) cyprius has been treated as a subspecies of the widespread Eurasian Scops Owl O. scops since at least the 1940s. However, its…

Continue ReadingReprising the taxonomy of Cyprus Scops Owl Otus (scops) cyprius, a neglected island endemic.
Read more about the article Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe.
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Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe.

Abstract Numerous studies have shown that baseline drug resistance patterns may influence the outcome of antiretroviral therapy. Therefore, guidelines recommend drug resistance testing to guide the choice of initial regimen.…

Continue ReadingTransmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe.
Read more about the article Glioblastoma Stem Cells as a New Therapeutic Target for Glioblastoma.
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Glioblastoma Stem Cells as a New Therapeutic Target for Glioblastoma.

Abstract Primary and secondary glioblastomas (GBMs) are two distinct diseases. The genetic and epigenetic background of these tumors is highly variable. The treatment procedure for these tumors is often unsuccessful…

Continue ReadingGlioblastoma Stem Cells as a New Therapeutic Target for Glioblastoma.
Read more about the article An Evolutionarily Young Polar Bear (Ursus maritimus) Endogenous Retrovirus Identified from Next Generation Sequence Data.
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An Evolutionarily Young Polar Bear (Ursus maritimus) Endogenous Retrovirus Identified from Next Generation Sequence Data.

Abstract Transcriptome analysis of polar bear (Ursus maritimus) tissues identified sequences with similarity to Porcine Endogenous Retroviruses (PERV). Based on these sequences, four proviral copies and 15 solo long terminal…

Continue ReadingAn Evolutionarily Young Polar Bear (Ursus maritimus) Endogenous Retrovirus Identified from Next Generation Sequence Data.
Read more about the article Newly isolated alkalophilic Advenella species bioaugmented in activated sludge for high p-cresol removal.
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Newly isolated alkalophilic Advenella species bioaugmented in activated sludge for high p-cresol removal.

Abstract In this work, an alkalophilic bacterium (LVX-4) capable of using p-cresol as sole source of carbon and energy was screened and isolated from soil polluted by used oil. Phylogenetic…

Continue ReadingNewly isolated alkalophilic Advenella species bioaugmented in activated sludge for high p-cresol removal.
Read more about the article Identifying Non-Duchenne Muscular Dystrophy-Positive and False Negative Results in Prior Duchenne Muscular Dystrophy Newborn Screening Programs: A Review.
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Identifying Non-Duchenne Muscular Dystrophy-Positive and False Negative Results in Prior Duchenne Muscular Dystrophy Newborn Screening Programs: A Review.

Abstract Duchenne muscular dystrophy (DMD) is a candidate for the recommended universal screening panel based on evidence that early corticosteroid treatment improves outcomes and on new genetic therapies that require…

Continue ReadingIdentifying Non-Duchenne Muscular Dystrophy-Positive and False Negative Results in Prior Duchenne Muscular Dystrophy Newborn Screening Programs: A Review.
Read more about the article Sex-specific age association with primary DNA transfer.
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Sex-specific age association with primary DNA transfer.

Abstract Practicing forensic scientists who are called to provide expert witness testimony are often asked to explain both the presence and the absence of DNA on objects that have been…

Continue ReadingSex-specific age association with primary DNA transfer.