Read more about the article Four novel mutations in patients from the Middle East with the infantile form of GM1-gangliosidosis.
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Four novel mutations in patients from the Middle East with the infantile form of GM1-gangliosidosis.

Abstract GM1-gangliosidosis is a lysosomal storage disorder caused by a deficiency of beta-galactosidase. It is mainly characterized by progressive neurodegeneration and in its most severe infantile form it leads to…

Continue ReadingFour novel mutations in patients from the Middle East with the infantile form of GM1-gangliosidosis.
Read more about the article Preimplantation HLA typing and stem cell transplantation: report of International Meeting, Cyprus, 27-8 March, 2004.
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Preimplantation HLA typing and stem cell transplantation: report of International Meeting, Cyprus, 27-8 March, 2004.

Abstract There has been progress in the application of stem cell transplantation for the treatment of an increasing number of severe congenital and acquired bone marrow disorders that are currently…

Continue ReadingPreimplantation HLA typing and stem cell transplantation: report of International Meeting, Cyprus, 27-8 March, 2004.
Read more about the article Description of the first two seemingly unrelated Greek Cypriot families with a common C618R RET proto-oncogene mutation.
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Description of the first two seemingly unrelated Greek Cypriot families with a common C618R RET proto-oncogene mutation.

Abstract Germ-line mutations of the RET proto-oncogene cause three different cancer syndromes: multiple endocrine neoplasia type 2A (MEN2A), multiple endocrine neoplasia type 2B, and familial medullary thyroid carcinoma (FMTC). The…

Continue ReadingDescription of the first two seemingly unrelated Greek Cypriot families with a common C618R RET proto-oncogene mutation.
Read more about the article Restoration of protein synthesis in pancreatic cancer cells by trans-splicing ribozymes.
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Restoration of protein synthesis in pancreatic cancer cells by trans-splicing ribozymes.

Abstract This report describes the use of trans-splicing ribozymes to restore p16 protein synthesis in pancreatic cancer cells. A group I intron ribozyme was designed to trans-splice the 2 base-deleted…

Continue ReadingRestoration of protein synthesis in pancreatic cancer cells by trans-splicing ribozymes.
Read more about the article Distribution and functions of kinectin isoforms.
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Distribution and functions of kinectin isoforms.

Abstract Kinectin is an integral transmembrane protein on the endoplasmic reticulum, binding to kinesin, interacting with Rho GTPase and anchoring the translation elongation factor-1 complex. There has been debate on…

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Read more about the article Choosing eugenics: how far will nations go to eliminate a genetic disease?
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Choosing eugenics: how far will nations go to eliminate a genetic disease?

Abstract

Continue ReadingChoosing eugenics: how far will nations go to eliminate a genetic disease?
Read more about the article [A new species of wild mice on the Island of Cyprus].
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[A new species of wild mice on the Island of Cyprus].

Abstract A mitochondrial and nuclear gene analysis allowed us to precise the taxonomical position of the two sympatric species of mice known to be present on Cyprus. One of them…

Continue Reading[A new species of wild mice on the Island of Cyprus].
Read more about the article Blood lead levels in preprimary school-age children in Nicosia, Cyprus, and their relationship with leaded soil dust exposure.
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Blood lead levels in preprimary school-age children in Nicosia, Cyprus, and their relationship with leaded soil dust exposure.

Abstract The authors conducted a cross-sectional study to determine blood lead levels in children who attended kindergarten schools and nurseries in Nicosia, Cyprus, and to correlate their findings with (a)…

Continue ReadingBlood lead levels in preprimary school-age children in Nicosia, Cyprus, and their relationship with leaded soil dust exposure.
Read more about the article Allozyme variability and phylogenetic relationships in honey bee (Hymenoptera: Apidae: Apis mellifera) populations from Greece and Cyprus.
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Allozyme variability and phylogenetic relationships in honey bee (Hymenoptera: Apidae: Apis mellifera) populations from Greece and Cyprus.

Abstract Ten gene enzymic systems (alpha-GPDH, AO, MDH, ADH, LAP, SOD, ALP, ACPH, ME, and EST), corresponding to 12 genetic loci, were assayed from five Greek populations representing three subspecies…

Continue ReadingAllozyme variability and phylogenetic relationships in honey bee (Hymenoptera: Apidae: Apis mellifera) populations from Greece and Cyprus.
Read more about the article Novel polymorphisms at codons 146 and 151 in the prion protein gene of Cyprus goats, and their association with natural scrapie.
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Novel polymorphisms at codons 146 and 151 in the prion protein gene of Cyprus goats, and their association with natural scrapie.

Abstract To discern whether an association exists between specific combinations of polymorphisms of the prion protein (PrP) and natural scrapie in Cyprus goats, 250 goats were examined, including 164 histologically…

Continue ReadingNovel polymorphisms at codons 146 and 151 in the prion protein gene of Cyprus goats, and their association with natural scrapie.