Read more about the article Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: genetic and structural in silico analyses.
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Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: genetic and structural in silico analyses.

Abstract The extensive polymorphisms among HIV-1 subtypes have been implicated in drug resistance development. Integrase inhibitors represent the latest addition to the treatment of HIV-1, and their efficacy and resistance…

Continue ReadingImplications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: genetic and structural in silico analyses.
Read more about the article The labyrinth of bone disease in thalassaemia: the search for Ariadne’s thread continues.
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The labyrinth of bone disease in thalassaemia: the search for Ariadne’s thread continues.

Abstract

Continue ReadingThe labyrinth of bone disease in thalassaemia: the search for Ariadne’s thread continues.
Read more about the article Association of mild and severely unstable alpha chain variants: the first observation of a compound heterozygote with Hb Setif [alpha94(G1)Asp–>Tyr (alpha2)] and Hb Agrinio [alpha29(B10)Leu–>Pro (alpha2)] in a Greek family.
A rolled newspaper - the left side facing forward. The name of the newspaper is "News" and the words "News" and "Events" are below that. The rubber band keeping the newspaper rolled together is thick and white. There is smaller writing on the newspaper which cannot be read.

Association of mild and severely unstable alpha chain variants: the first observation of a compound heterozygote with Hb Setif [alpha94(G1)Asp–>Tyr (alpha2)] and Hb Agrinio [alpha29(B10)Leu–>Pro (alpha2)] in a Greek family.

Abstract Hb Setif is a relatively rare, mildly unstable alpha2-globin hemoglobin (Hb) variant first described in an Algerian family, and subsequently in various populations of the Mediterranean region and the…

Continue ReadingAssociation of mild and severely unstable alpha chain variants: the first observation of a compound heterozygote with Hb Setif [alpha94(G1)Asp–>Tyr (alpha2)] and Hb Agrinio [alpha29(B10)Leu–>Pro (alpha2)] in a Greek family.
Read more about the article Serum total homocysteine, folate, 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C–>T genotype and subclinical atherosclerosis.
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Serum total homocysteine, folate, 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C–>T genotype and subclinical atherosclerosis.

Abstract To determine the relationship of serum total homocysteine (tHcy), serum folate and 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T genotype with ultrasonic arterial wall measurements associated with subclinical atherosclerosis. Cross-sectional analysis of…

Continue ReadingSerum total homocysteine, folate, 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C–>T genotype and subclinical atherosclerosis.
Read more about the article Low HDL cholesterol, smoking and IL-13 R130Q polymorphism are associated with myocardial infarction in Greek Cypriot males. A pilot study.
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Low HDL cholesterol, smoking and IL-13 R130Q polymorphism are associated with myocardial infarction in Greek Cypriot males. A pilot study.

Abstract This study was carried out in Greek Cypriot males to identify risk factors that predispose to myocardial infarction (MI). Genetic and lipid risk factors were investigated for the first…

Continue ReadingLow HDL cholesterol, smoking and IL-13 R130Q polymorphism are associated with myocardial infarction in Greek Cypriot males. A pilot study.
Read more about the article A new neurogenic vestibular evoked potential (N6) recorded with the use of air-conducted sound.
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A new neurogenic vestibular evoked potential (N6) recorded with the use of air-conducted sound.

Abstract Neurogenic vestibular evoked potentials that are recorded from the scalp have so far been recorded in the form of N3 (click air-conducted), N5 (tone air-conducted), and P10 (bone-conducted stimulus)…

Continue ReadingA new neurogenic vestibular evoked potential (N6) recorded with the use of air-conducted sound.
Read more about the article PrP gene polymorphisms in Cyprus goats and their association with resistance or susceptibility to natural scrapie.
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PrP gene polymorphisms in Cyprus goats and their association with resistance or susceptibility to natural scrapie.

Abstract In contrast to scrapie in sheep, the genetic basis of susceptibility to scrapie in goats is not well understood. To study the association of prion protein (PrP) alleles with…

Continue ReadingPrP gene polymorphisms in Cyprus goats and their association with resistance or susceptibility to natural scrapie.
Read more about the article CRF45_AKU, a circulating recombinant from Central Africa, is probably the common ancestor of HIV type 1 MAL and HIV type 1 NOGIL.
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CRF45_AKU, a circulating recombinant from Central Africa, is probably the common ancestor of HIV type 1 MAL and HIV type 1 NOGIL.

Abstract Abstract In this study, we characterized four HIV-1 strains from Cameroon, Gabon, and the Democratic Republic of Congo (DRC), collected during independent serosurveys, and previously found to cluster in…

Continue ReadingCRF45_AKU, a circulating recombinant from Central Africa, is probably the common ancestor of HIV type 1 MAL and HIV type 1 NOGIL.
Read more about the article Discovering genetic polymorphism associated with gene expression levels across the whole genome.
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Discovering genetic polymorphism associated with gene expression levels across the whole genome.

Abstract Genetic differences have been shown to contribute to gene expression variability. A complete evaluation of the associations between a whole genome scan with 550k Single Nucleotide Polymorphisms (SNPs) and…

Continue ReadingDiscovering genetic polymorphism associated with gene expression levels across the whole genome.
Read more about the article Assessing the potential success of cystic fibrosis carrier screening: lessons learned from Tay-Sachs disease and beta-thalassemia.
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Assessing the potential success of cystic fibrosis carrier screening: lessons learned from Tay-Sachs disease and beta-thalassemia.

Abstract The objective of this study was to identify factors involved in the success of 2 well-established population-based carrier screening programs - Tay-Sachs disease (TSD) in Ashkenazi Jews and beta-thalassemia…

Continue ReadingAssessing the potential success of cystic fibrosis carrier screening: lessons learned from Tay-Sachs disease and beta-thalassemia.