Read more about the article Measurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR.
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Measurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR.

Abstract Lentiviruses are the vectors of choice for many preclinical studies and clinical applications of gene therapy. Accurate measurement of biological vector titre before treatment is a prerequisite for vector…

Continue ReadingMeasurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR.
Read more about the article Carriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.
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Carriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.

Abstract Collagen IV nephropathies (COL4Ns) comprise benign familial microscopic hematuria, thin basement membrane nephropathy (TBMN), X-linked Alport syndrome (AS) and also autosomal recessive and dominant AS. Apart from the X-linked…

Continue ReadingCarriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.
Read more about the article Primary resistance to integrase strand-transfer inhibitors in Europe.
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Primary resistance to integrase strand-transfer inhibitors in Europe.

Abstract The objective of this study was to define the natural genotypic variation of the HIV-1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer inhibitor (InSTI) resistance. This…

Continue ReadingPrimary resistance to integrase strand-transfer inhibitors in Europe.
Read more about the article Near East University Genetic Mutation Database (NEU-GD): The first mutation database of Northern Cyprus.
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Near East University Genetic Mutation Database (NEU-GD): The first mutation database of Northern Cyprus.

Abstract The health care system is negatively affected by the genetic disorders that lead to an increasing rate of morbidity and neonatal deaths and affect adults as well. These create…

Continue ReadingNear East University Genetic Mutation Database (NEU-GD): The first mutation database of Northern Cyprus.
Read more about the article Homo sapiens exhibit a distinct pattern of CNV genes regulation: an important role of miRNAs and SNPs in expression plasticity.
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Homo sapiens exhibit a distinct pattern of CNV genes regulation: an important role of miRNAs and SNPs in expression plasticity.

Abstract Gene expression regulation is a complex and highly organized process involving a variety of genomic factors. It is widely accepted that differences in gene expression can contribute to the…

Continue ReadingHomo sapiens exhibit a distinct pattern of CNV genes regulation: an important role of miRNAs and SNPs in expression plasticity.
Read more about the article Microbial quality and molecular identification of cultivable microorganisms isolated from an urban drinking water distribution system (Limassol, Cyprus).
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Microbial quality and molecular identification of cultivable microorganisms isolated from an urban drinking water distribution system (Limassol, Cyprus).

Abstract Microorganisms can survive and multiply in aged urban drinking water distribution systems, leading to potential health risks. The objective of this work was to investigate the microbial quality of…

Continue ReadingMicrobial quality and molecular identification of cultivable microorganisms isolated from an urban drinking water distribution system (Limassol, Cyprus).
Read more about the article Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFNγ, MMP-2, IGF-II, EGF, TGF-β, IGF-IIR) during pregnancy in the cat uterus.
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Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFNγ, MMP-2, IGF-II, EGF, TGF-β, IGF-IIR) during pregnancy in the cat uterus.

Abstract Early pregnancy is one of the most critical periods of pregnancy, and many factors such as cytokines, enzymes, and members of the immune system have to cooperate in a…

Continue ReadingGene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFNγ, MMP-2, IGF-II, EGF, TGF-β, IGF-IIR) during pregnancy in the cat uterus.
Read more about the article Hypoxia Is the Driving Force Behind GBM and Could Be a New Tool in GBM Treatment.
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Hypoxia Is the Driving Force Behind GBM and Could Be a New Tool in GBM Treatment.

Abstract Glioblastoma (GBM) can be divided into two distinct disease entities according to the genetic and the epigenetic background of the tumor. Tumor location is associated with high variability in…

Continue ReadingHypoxia Is the Driving Force Behind GBM and Could Be a New Tool in GBM Treatment.
Read more about the article Glioblastoma Multiforme: The Genetic Perspective of the Treatment Planning.
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Glioblastoma Multiforme: The Genetic Perspective of the Treatment Planning.

Abstract Glioblastoma multiforme (GBM) is divided into two distinct disease entities called primary and secondary GBM. The genetic and the epigenetic background of these tumors are highly variable. These tumors…

Continue ReadingGlioblastoma Multiforme: The Genetic Perspective of the Treatment Planning.
Read more about the article Temporal analysis reveals a key role for VTE5 in vitamin E biosynthesis in olive fruit during on-tree development.
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Temporal analysis reveals a key role for VTE5 in vitamin E biosynthesis in olive fruit during on-tree development.

Abstract The aim of this work was to generate a high resolution temporal mapping of the biosynthetic pathway of vitamin E in olive fruit (Olea europaea cv. "Koroneiki") during 17…

Continue ReadingTemporal analysis reveals a key role for VTE5 in vitamin E biosynthesis in olive fruit during on-tree development.