Read more about the article Early life course risk factors for childhood obesity: the IDEFICS case-control study.
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Early life course risk factors for childhood obesity: the IDEFICS case-control study.

Abstract The early life course is assumed to be a critical phase for childhood obesity; however the significance of single factors and their interplay is not well studied in childhood…

Continue ReadingEarly life course risk factors for childhood obesity: the IDEFICS case-control study.
Read more about the article Population genetics of 17 Y-STR markers in Turkish Cypriots from Cyprus.
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Population genetics of 17 Y-STR markers in Turkish Cypriots from Cyprus.

Abstract We analyzed seventeen Y-chromosomal short tandem repeats (STRs) [DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y-GATA-H4, DYS437, DYS438, and DYS448] in 253 unrelated, male…

Continue ReadingPopulation genetics of 17 Y-STR markers in Turkish Cypriots from Cyprus.
Read more about the article Genotyping of BCL11A and HBS1L-MYB SNPs associated with fetal haemoglobin levels: a SNaPshot minisequencing approach.
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Genotyping of BCL11A and HBS1L-MYB SNPs associated with fetal haemoglobin levels: a SNaPshot minisequencing approach.

Abstract B-thalassaemia and sickle cell disease (SCD) are two of the most common monogenic diseases that are found in many populations worldwide. In both disorders the clinical severity is highly…

Continue ReadingGenotyping of BCL11A and HBS1L-MYB SNPs associated with fetal haemoglobin levels: a SNaPshot minisequencing approach.
Read more about the article Epidemiology of respiratory syncytial virus in children in Cyprus during three consecutive winter seasons (2010-2013): age distribution, seasonality and association between prevalent genotypes and disease severity.
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Epidemiology of respiratory syncytial virus in children in Cyprus during three consecutive winter seasons (2010-2013): age distribution, seasonality and association between prevalent genotypes and disease severity.

Abstract This study reports the epidemiology of respiratory syncytial virus (RSV) in hospitalized children in Cyprus over three successive seasons (2010-2013) and the association between prevalent genotypes and disease severity.…

Continue ReadingEpidemiology of respiratory syncytial virus in children in Cyprus during three consecutive winter seasons (2010-2013): age distribution, seasonality and association between prevalent genotypes and disease severity.
Read more about the article X-linked, COL4A5 hypomorphic Alport mutations such as G624D and P628L may only exhibit thin basement membrane nephropathy with microhematuria and late onset kidney failure.
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X-linked, COL4A5 hypomorphic Alport mutations such as G624D and P628L may only exhibit thin basement membrane nephropathy with microhematuria and late onset kidney failure.

Abstract Alport syndrome (ATS) results from X-linked, COL4A5 mutations (85%) or from autosomal recessive homozygous or compound heterozygous COL4A3/A4 mutations (15%), associated with alternate thinning and thickening as well as…

Continue ReadingX-linked, COL4A5 hypomorphic Alport mutations such as G624D and P628L may only exhibit thin basement membrane nephropathy with microhematuria and late onset kidney failure.
Read more about the article Will the introduction of Leishmania tropica MON-58, in the island of Crete, lead to the settlement and spread of this rare zymodeme?
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Will the introduction of Leishmania tropica MON-58, in the island of Crete, lead to the settlement and spread of this rare zymodeme?

Abstract The rare zymodeme, Leishmania tropica MON-58, was isolated from a young Afghan refugee with a facial cutaneous lesion who had come to live in Crete early 2008. The same…

Continue ReadingWill the introduction of Leishmania tropica MON-58, in the island of Crete, lead to the settlement and spread of this rare zymodeme?
Read more about the article Hb Famagusta–analysis of a novel δ-globin chain variant [HBD:c.60C>A] in four families with diverse globin genotypes.
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Hb Famagusta–analysis of a novel δ-globin chain variant [HBD:c.60C>A] in four families with diverse globin genotypes.

Abstract

Continue ReadingHb Famagusta–analysis of a novel δ-globin chain variant [HBD:c.60C>A] in four families with diverse globin genotypes.
Read more about the article JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.
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JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.

Abstract Mammography is an important screening modality for the early detection of DCIS and breast cancer lesions. More specifically, high mammographic density is associated with an increased risk of breast…

Continue ReadingJNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.
Read more about the article Making the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton.
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Making the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton.

Abstract Cilia have been associated with diverse developmental and physiological processes, and defects in cilia underlie a number of genetic conditions. Several lines of evidence support a critical role of…

Continue ReadingMaking the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton.
Read more about the article miR-186 inhibits muscle cell differentiation through myogenin regulation.
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miR-186 inhibits muscle cell differentiation through myogenin regulation.

Abstract The complex process of skeletal muscle differentiation is organized by the myogenic regulatory factors (MRFs), Myf5, MyoD, Myf6, and myogenin, where myogenin plays a critical role in the regulation…

Continue ReadingmiR-186 inhibits muscle cell differentiation through myogenin regulation.