Read more about the article Making the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton.
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Making the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton.

Abstract Cilia have been associated with diverse developmental and physiological processes, and defects in cilia underlie a number of genetic conditions. Several lines of evidence support a critical role of…

Continue ReadingMaking the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton.
Read more about the article miR-186 inhibits muscle cell differentiation through myogenin regulation.
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miR-186 inhibits muscle cell differentiation through myogenin regulation.

Abstract The complex process of skeletal muscle differentiation is organized by the myogenic regulatory factors (MRFs), Myf5, MyoD, Myf6, and myogenin, where myogenin plays a critical role in the regulation…

Continue ReadingmiR-186 inhibits muscle cell differentiation through myogenin regulation.
Read more about the article A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis.
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A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis.

Abstract Double-seronegative myasthenia gravis (dSN-MG, without detectable AChR and MuSK antibodies) presents a serious gap in MG diagnosis and understanding. Recently, autoantibodies against the low-density lipoprotein receptor-related protein 4 (LRP4)…

Continue ReadingA comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis.
Read more about the article Country-specific dietary patterns and associations with socioeconomic status in European children: the IDEFICS study.
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Country-specific dietary patterns and associations with socioeconomic status in European children: the IDEFICS study.

Abstract Children from lower socioeconomic status (SES) may be at higher risk of unhealthy eating. We described country-specific dietary patterns among children aged 2-9 years from eight European countries participating…

Continue ReadingCountry-specific dietary patterns and associations with socioeconomic status in European children: the IDEFICS study.
Read more about the article HCV NS5A co-operates with PKR in modulating HCV IRES-dependent translation.
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HCV NS5A co-operates with PKR in modulating HCV IRES-dependent translation.

Abstract Translation initiation of the Hepatitis C virus (HCV) genome is driven by an internal ribosome entry site (IRES), located within the 5' non-coding region. Several studies have suggested that…

Continue ReadingHCV NS5A co-operates with PKR in modulating HCV IRES-dependent translation.
Read more about the article Using microRNA profiles to predict and evaluate hepatic carcinogenic potential.
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Using microRNA profiles to predict and evaluate hepatic carcinogenic potential.

Abstract Novel chemical entities have to be assessed for potential adverse effects in exposed human populations, including increased cancer incidence. The liver is an organ of particular interest for such…

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Read more about the article A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.
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A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.

Abstract This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity 2years after radiotherapy. A genome wide association study was performed in 1850 patients from the…

Continue ReadingA genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.
Read more about the article Despeckle Filtering for Multiscale Amplitude-Modulation Frequency-Modulation (AM-FM) Texture Analysis of Ultrasound Images of the Intima-Media Complex.
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Despeckle Filtering for Multiscale Amplitude-Modulation Frequency-Modulation (AM-FM) Texture Analysis of Ultrasound Images of the Intima-Media Complex.

Abstract The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of cardiovascular disease (CVD). Typically, the IMT grows with age and this…

Continue ReadingDespeckle Filtering for Multiscale Amplitude-Modulation Frequency-Modulation (AM-FM) Texture Analysis of Ultrasound Images of the Intima-Media Complex.
Read more about the article The Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis.
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The Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis.

Abstract Epigenetic modifications have proven to play a significant role in cancer development, as well as fetal development. Taking advantage of the knowledge acquired during the last decade, great interest…

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Read more about the article Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.
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Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.

Abstract There is growing evidence for the involvement of Y-complex nucleoporins (Y-Nups) in cellular processes beyond the inner core of nuclear pores of eukaryotes. To comprehensively assess the range of…

Continue ReadingFunctional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.