Read more about the article Ribozyme gene therapy.
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Ribozyme gene therapy.

Abstract

Continue ReadingRibozyme gene therapy.
Read more about the article Mutations of the human polycystic kidney disease 2 (PKD2) gene.
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Mutations of the human polycystic kidney disease 2 (PKD2) gene.

Abstract Autosomal dominant polycystic kidney disease (ADPKD) is an inherited nephropathy, usually of late onset (onset between third to seventh decade), primarily characterized by the formation of fluid-filled cysts in…

Continue ReadingMutations of the human polycystic kidney disease 2 (PKD2) gene.
Read more about the article Evidence of two distinct subsubtypes within the HIV-1 subtype A radiation.
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Evidence of two distinct subsubtypes within the HIV-1 subtype A radiation.

Abstract Members of HIV-1 group M are responsible for the vast majority of AIDS cases worldwide and have been classified on the basis of their phylogenetic relationships into nine roughly…

Continue ReadingEvidence of two distinct subsubtypes within the HIV-1 subtype A radiation.
Read more about the article The MNSs blood group system in the population of South Backa.
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The MNSs blood group system in the population of South Backa.

Abstract Blood groups represent qualitative characteristics of humans which are controlled by one or a few genetic loci and due to this it is easy to determine various kinds of…

Continue ReadingThe MNSs blood group system in the population of South Backa.
Read more about the article Population genetics of factor V Leiden in Europe.
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Population genetics of factor V Leiden in Europe.

Abstract We have analyzed 5971 control individuals originating from 26 geographically defined populations in Europe and neighboring countries for the presence of factor V Leiden, an important genetic risk factor…

Continue ReadingPopulation genetics of factor V Leiden in Europe.
Read more about the article The molecular characterization of 16 new sequence variants of Hop stunt viroid reveals the existence of invariable regions and a conserved hammerhead-like structure on the viroid molecule.
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The molecular characterization of 16 new sequence variants of Hop stunt viroid reveals the existence of invariable regions and a conserved hammerhead-like structure on the viroid molecule.

Abstract At present isolates of Hop stunt viroid (HSVd) are divided into five groups: three major groups (plum-type, hop-type and citrus-type) each containing isolates from only a limited number of…

Continue ReadingThe molecular characterization of 16 new sequence variants of Hop stunt viroid reveals the existence of invariable regions and a conserved hammerhead-like structure on the viroid molecule.
Read more about the article A nation-based population screening for azoospermia factor deletions in Greek-Cypriot patients with severe spermatogenic failure and normal fertile controls, using a specific study and experimental design.
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A nation-based population screening for azoospermia factor deletions in Greek-Cypriot patients with severe spermatogenic failure and normal fertile controls, using a specific study and experimental design.

Abstract Y chromosome microdeletions in the azoospermia factor (AZF) locus have been associated with spermatogenic failure. The frequency of AZF deletions is estimated to be about 10-18% in subgroups of…

Continue ReadingA nation-based population screening for azoospermia factor deletions in Greek-Cypriot patients with severe spermatogenic failure and normal fertile controls, using a specific study and experimental design.
Read more about the article Novel NPR1 polymorphic variants and its exclusion as a candidate gene for medullary cystic kidney disease (ADMCKD) type 1.
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Novel NPR1 polymorphic variants and its exclusion as a candidate gene for medullary cystic kidney disease (ADMCKD) type 1.

Abstract Autosomal dominant medullary cystic kidney disease (ADMCKD) is an adult-onset heterogeneous genetic nephropathy characterized by salt wasting and end-stage renal failure. The gene responsible for ADMCKD-1 was mapped on…

Continue ReadingNovel NPR1 polymorphic variants and its exclusion as a candidate gene for medullary cystic kidney disease (ADMCKD) type 1.
Read more about the article BRCA1 germline mutations in Cypriot breast cancer patients from 26 families with family history.
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BRCA1 germline mutations in Cypriot breast cancer patients from 26 families with family history.

Abstract Germline mutations in the BRCA1 gene are causative for a variable number of hereditary breast/ovarian cancers. The data presented in this study are based on genetic analysis of the…

Continue ReadingBRCA1 germline mutations in Cypriot breast cancer patients from 26 families with family history.
Read more about the article Clinical results with direct thrombin inhibitors.
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Clinical results with direct thrombin inhibitors.

Abstract Direct thrombin inhibitors inactivate thrombin without the need for antithrombin and some inactivate not only thrombin but also fibrin-bound thrombin. Hirudin has been shown to be more effective than…

Continue ReadingClinical results with direct thrombin inhibitors.