Read more about the article Correlation between morphology, immunohistochemistry and molecular pathology in hereditary and sporadic breast cancer cases.
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Correlation between morphology, immunohistochemistry and molecular pathology in hereditary and sporadic breast cancer cases.

Abstract Breast cancer still represents a serious health problem and is currently the most frequent malignancy in the female population in developed countries. In Cyprus, there are 300 new cases…

Continue ReadingCorrelation between morphology, immunohistochemistry and molecular pathology in hereditary and sporadic breast cancer cases.
Read more about the article Familial Mediterranean fever (FMF) mutations occur frequently in the Greek-Cypriot population of Cyprus.
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Familial Mediterranean fever (FMF) mutations occur frequently in the Greek-Cypriot population of Cyprus.

Abstract Familial Mediterranean Fever (FMF) is an autosomal recessive disease of high prevalence within Mediterranean countries and particularly common in four ethnic populations: Arabs, non-Ashkenazi Jews, Armenians, and Turks. The…

Continue ReadingFamilial Mediterranean fever (FMF) mutations occur frequently in the Greek-Cypriot population of Cyprus.
Read more about the article ITS 2 sequences heterogeneity in Phlebotomus sergenti and Phlebotomus similis (Diptera, Psychodidae): possible consequences in their ability to transmit Leishmania tropica.
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ITS 2 sequences heterogeneity in Phlebotomus sergenti and Phlebotomus similis (Diptera, Psychodidae): possible consequences in their ability to transmit Leishmania tropica.

Abstract An intraspecific study on Phlebotomus sergenti, the main and only proven vector of Leishmania tropica among the members of the subgenus Paraphlebotomus was performed. The internal transcribed spacer 2…

Continue ReadingITS 2 sequences heterogeneity in Phlebotomus sergenti and Phlebotomus similis (Diptera, Psychodidae): possible consequences in their ability to transmit Leishmania tropica.
Read more about the article Clinical results with direct thrombin inhibitors.
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Clinical results with direct thrombin inhibitors.

Abstract Direct thrombin inhibitors inactivate thrombin without the need for antithrombin and some inactivate not only thrombin but also fibrin-bound thrombin. Hirudin has been shown to be more effective than…

Continue ReadingClinical results with direct thrombin inhibitors.
Read more about the article A4T mutation in the SOD1 gene causing familial amyotrophic lateral sclerosis.
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A4T mutation in the SOD1 gene causing familial amyotrophic lateral sclerosis.

Abstract We report the clinical and laboratory findings in the largest kindred so far recorded with familial amyotrophic lateral sclerosis due to an A4T mutation in the SOD1 gene. The…

Continue ReadingA4T mutation in the SOD1 gene causing familial amyotrophic lateral sclerosis.
Read more about the article BRCA2 germline mutations in Cypriot patients with familial breast/ovarian cancer.
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BRCA2 germline mutations in Cypriot patients with familial breast/ovarian cancer.

Abstract Germline mutations in the BRCA2 gene have been shown to be associated with familial female and male breast cancer. Mutations occur throughout the entire coding region of the gene,…

Continue ReadingBRCA2 germline mutations in Cypriot patients with familial breast/ovarian cancer.
Read more about the article Spectrum and prevalence of prothrombotic single nucleotide polymorphism profiles in the Greek Cypriot population.
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Spectrum and prevalence of prothrombotic single nucleotide polymorphism profiles in the Greek Cypriot population.

Abstract This study was performed to establish the allele, genotype and genotype combination/SNP (single nucleotide polymorphism) profile frequencies in the general population of Cyprus for 6 genes implicated in thrombotic…

Continue ReadingSpectrum and prevalence of prothrombotic single nucleotide polymorphism profiles in the Greek Cypriot population.
Read more about the article A novel NF-L mutation Pro22Ser is associated with CMT2 in a large Slovenian family.
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A novel NF-L mutation Pro22Ser is associated with CMT2 in a large Slovenian family.

Abstract Charcot-Marie-Tooth (CMT) disease is the most-common form of inherited motor and sensory neuropathy. The autosomal dominant axonal form of the disease (CMT2) is currently subdivided into seven types based…

Continue ReadingA novel NF-L mutation Pro22Ser is associated with CMT2 in a large Slovenian family.
Read more about the article DNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis.
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DNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis.

Abstract DNazymes is a group of catalytic nucleic acids that can be designed to cleave target mRNA molecules in a base-specific way. Twist is a basic helix-loop-helix transcription factor that…

Continue ReadingDNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis.