Read more about the article DNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis.
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DNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis.

Abstract DNazymes is a group of catalytic nucleic acids that can be designed to cleave target mRNA molecules in a base-specific way. Twist is a basic helix-loop-helix transcription factor that…

Continue ReadingDNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis.
Read more about the article Phylogeographical variation of chloroplast DNA in holm oak (Quercus ilex L.).
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Phylogeographical variation of chloroplast DNA in holm oak (Quercus ilex L.).

Abstract Variation in the lengths of restriction fragments (RFLPs) of the whole chloroplast DNA molecule was studied in 174 populations of Quercus ilex L. sampled over the entire distribution of…

Continue ReadingPhylogeographical variation of chloroplast DNA in holm oak (Quercus ilex L.).
Read more about the article Effects of transmission of Y chromosome AZFc deletions.
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Effects of transmission of Y chromosome AZFc deletions.

Abstract Deletions of specific regions on the Y chromosome cause male infertility. Recent advances in infertility treatment allow Y chromosome deletions to be transmitted to male offspring with the assumption…

Continue ReadingEffects of transmission of Y chromosome AZFc deletions.
Read more about the article Autosomal-dominant medullary cystic kidney disease type 1: clinical and molecular findings in six large Cypriot families.
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Autosomal-dominant medullary cystic kidney disease type 1: clinical and molecular findings in six large Cypriot families.

Abstract Autosomal-dominant medullary cystic kidney disease (ADMCKD), a hereditary chronic interstitial nephropathy, recently attracted attention because of the cloning or mapping of certain gene loci, namely NPHP1, NPHP2 and NPHP3…

Continue ReadingAutosomal-dominant medullary cystic kidney disease type 1: clinical and molecular findings in six large Cypriot families.
Read more about the article Correlation between morphology, immunohistochemistry and molecular pathology in hereditary and sporadic breast cancer cases.
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Correlation between morphology, immunohistochemistry and molecular pathology in hereditary and sporadic breast cancer cases.

Abstract Breast cancer still represents a serious health problem and is currently the most frequent malignancy in the female population in developed countries. In Cyprus, there are 300 new cases…

Continue ReadingCorrelation between morphology, immunohistochemistry and molecular pathology in hereditary and sporadic breast cancer cases.
Read more about the article Familial Mediterranean fever (FMF) mutations occur frequently in the Greek-Cypriot population of Cyprus.
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Familial Mediterranean fever (FMF) mutations occur frequently in the Greek-Cypriot population of Cyprus.

Abstract Familial Mediterranean Fever (FMF) is an autosomal recessive disease of high prevalence within Mediterranean countries and particularly common in four ethnic populations: Arabs, non-Ashkenazi Jews, Armenians, and Turks. The…

Continue ReadingFamilial Mediterranean fever (FMF) mutations occur frequently in the Greek-Cypriot population of Cyprus.
Read more about the article ITS 2 sequences heterogeneity in Phlebotomus sergenti and Phlebotomus similis (Diptera, Psychodidae): possible consequences in their ability to transmit Leishmania tropica.
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ITS 2 sequences heterogeneity in Phlebotomus sergenti and Phlebotomus similis (Diptera, Psychodidae): possible consequences in their ability to transmit Leishmania tropica.

Abstract An intraspecific study on Phlebotomus sergenti, the main and only proven vector of Leishmania tropica among the members of the subgenus Paraphlebotomus was performed. The internal transcribed spacer 2…

Continue ReadingITS 2 sequences heterogeneity in Phlebotomus sergenti and Phlebotomus similis (Diptera, Psychodidae): possible consequences in their ability to transmit Leishmania tropica.
Read more about the article Clinical results with direct thrombin inhibitors.
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Clinical results with direct thrombin inhibitors.

Abstract Direct thrombin inhibitors inactivate thrombin without the need for antithrombin and some inactivate not only thrombin but also fibrin-bound thrombin. Hirudin has been shown to be more effective than…

Continue ReadingClinical results with direct thrombin inhibitors.
Read more about the article A4T mutation in the SOD1 gene causing familial amyotrophic lateral sclerosis.
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A4T mutation in the SOD1 gene causing familial amyotrophic lateral sclerosis.

Abstract We report the clinical and laboratory findings in the largest kindred so far recorded with familial amyotrophic lateral sclerosis due to an A4T mutation in the SOD1 gene. The…

Continue ReadingA4T mutation in the SOD1 gene causing familial amyotrophic lateral sclerosis.