Read more about the article STUDIES ON THE DISTRIBUTION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY, THALASSEMIA, AND OTHER GENETIC TRAITS IN THE COASTAL AND MOUNTAIN VILLAGES OF CYPRUS.
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STUDIES ON THE DISTRIBUTION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY, THALASSEMIA, AND OTHER GENETIC TRAITS IN THE COASTAL AND MOUNTAIN VILLAGES OF CYPRUS.

Abstract

Continue ReadingSTUDIES ON THE DISTRIBUTION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY, THALASSEMIA, AND OTHER GENETIC TRAITS IN THE COASTAL AND MOUNTAIN VILLAGES OF CYPRUS.
Read more about the article AN ABNORMAL HAEMOGLOBIN (LEPORE/CYPRUS) RESEMBLING HAEMOGLOBIN-LEPORE AND ITS INTERACTION WITH THALASSAEMIA.
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AN ABNORMAL HAEMOGLOBIN (LEPORE/CYPRUS) RESEMBLING HAEMOGLOBIN-LEPORE AND ITS INTERACTION WITH THALASSAEMIA.

Abstract

Continue ReadingAN ABNORMAL HAEMOGLOBIN (LEPORE/CYPRUS) RESEMBLING HAEMOGLOBIN-LEPORE AND ITS INTERACTION WITH THALASSAEMIA.
Read more about the article Prevention of thalassaemia in Cyprus.
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Prevention of thalassaemia in Cyprus.

A programme for the prevention of beta-homozygous thalassaemia has been operating in Cyprus from 1973. From 1976 there has been an increasing gap between the number of homozygotes born and…

Continue ReadingPrevention of thalassaemia in Cyprus.
Read more about the article Thalassaemia as a model of recessive genetic disease in the community.
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Thalassaemia as a model of recessive genetic disease in the community.

Abstract In order to gain understanding of some of the problems of genetic counseling for a severe recessive disease in England, a Greek Cypriot extended family including 87 living members…

Continue ReadingThalassaemia as a model of recessive genetic disease in the community.
Read more about the article Triplicated alpha-globin loci in humans.
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Triplicated alpha-globin loci in humans.

Abstract We have identified 12 individuals who are heterozygous for a chromosome with three alpha-globin genes. We determined the presence of the third alpha-globin locus by restriction endonuclease digestion and…

Continue ReadingTriplicated alpha-globin loci in humans.
Read more about the article Molecular basis of hemoglobin-H disease in the Mediterranean population.
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Molecular basis of hemoglobin-H disease in the Mediterranean population.

Abstract We investigated the molecular basis of hemoglobin-H disease by hybridization and restriction endonuclease mapping of the DNA in the Mediterranean populations. Of the 12 patients studied from Cyprus and…

Continue ReadingMolecular basis of hemoglobin-H disease in the Mediterranean population.
Read more about the article Feasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.
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Feasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.

Abstract The feasibility of using restriction fragment length polymorphisms ( RFLPs ) for the antenatal diagnosis of beta thalassaemia in the U.K.-resident Cypriot and Asian Indian populations has been determined.…

Continue ReadingFeasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.
Read more about the article Association of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.
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Association of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.

Abstract A new polymorphic BgI II restriction endonuclease site in the alpha-globin gene complex has been found in Cypriot, Sardinian, and Greek populations. In all cases, this polymorphism is linked…

Continue ReadingAssociation of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.
Read more about the article Globin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.
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Globin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.

Abstract The genetic factors responsible for the relatively mild clinical phenotypes of some cases of homozygous beta zero thalassaemia (thalassaemia intermedia) in Sardinia have been evaluated. The frequency of deletion…

Continue ReadingGlobin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.