Read more about the article Feasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.
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Feasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.

Abstract The feasibility of using restriction fragment length polymorphisms ( RFLPs ) for the antenatal diagnosis of beta thalassaemia in the U.K.-resident Cypriot and Asian Indian populations has been determined.…

Continue ReadingFeasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.
Read more about the article Association of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.
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Association of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.

Abstract A new polymorphic BgI II restriction endonuclease site in the alpha-globin gene complex has been found in Cypriot, Sardinian, and Greek populations. In all cases, this polymorphism is linked…

Continue ReadingAssociation of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.
Read more about the article Globin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.
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Globin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.

Abstract The genetic factors responsible for the relatively mild clinical phenotypes of some cases of homozygous beta zero thalassaemia (thalassaemia intermedia) in Sardinia have been evaluated. The frequency of deletion…

Continue ReadingGlobin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.
Read more about the article Identification of two distinct amplifications of the esterase B locus in Culex pipiens (L.) mosquitoes from Mediterranean countries.
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Identification of two distinct amplifications of the esterase B locus in Culex pipiens (L.) mosquitoes from Mediterranean countries.

Abstract Two new highly active esterases were detected by starch electrophoretic studies in Culex pipiens mosquitoes from the area of Montpellier (France) and from Cyprus. We demonstrate here that both…

Continue ReadingIdentification of two distinct amplifications of the esterase B locus in Culex pipiens (L.) mosquitoes from Mediterranean countries.
Read more about the article delta F508 cystic fibrosis mutation appears very infrequently in the Greek-Cypriot community of Cyprus.
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delta F508 cystic fibrosis mutation appears very infrequently in the Greek-Cypriot community of Cyprus.

Abstract

Continue Readingdelta F508 cystic fibrosis mutation appears very infrequently in the Greek-Cypriot community of Cyprus.
Read more about the article Identification of four novel delta-globin gene mutations in Greek Cypriots using polymerase chain reaction and automated fluorescence-based DNA sequence analysis.
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Identification of four novel delta-globin gene mutations in Greek Cypriots using polymerase chain reaction and automated fluorescence-based DNA sequence analysis.

Abstract The molecular basis of most beta-thalassemia syndromes has been defined, while the spectrum of mutations causing delta-thalassemia is not well characterized. In an attempt to identify such mutations, the…

Continue ReadingIdentification of four novel delta-globin gene mutations in Greek Cypriots using polymerase chain reaction and automated fluorescence-based DNA sequence analysis.
Read more about the article Multiple sclerosis in Cyprus.
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Multiple sclerosis in Cyprus.

Abstract The prevalence of multiple sclerosis (MS) was studied in the Greek-speaking population in the southwestern district of Paphos and the eastern Famagusta area and in the Troodos mountains in…

Continue ReadingMultiple sclerosis in Cyprus.
Read more about the article Rapid detection and prenatal diagnosis of beta-thalassaemia: studies in Indian and Cypriot populations in the UK.
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Rapid detection and prenatal diagnosis of beta-thalassaemia: studies in Indian and Cypriot populations in the UK.

Abstract The application of the amplification refractory mutation system (ARMS) to the detection of individual beta-thalassaemia mutations in heterozygous parents and "at risk" fetuses has been assessed in Indian and…

Continue ReadingRapid detection and prenatal diagnosis of beta-thalassaemia: studies in Indian and Cypriot populations in the UK.
Read more about the article Problems in the control of genetic disorders.
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Problems in the control of genetic disorders.

Abstract Preventive genetics services based on population screening are now an integral part of maternal and child health programmes. New developments in DNA technology, ultrasound scanning, and assay of factors…

Continue ReadingProblems in the control of genetic disorders.
Read more about the article Beta thalassaemia mutations in Turkish Cypriots.
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Beta thalassaemia mutations in Turkish Cypriots.

Abstract Using oligonucleotide hybridisation or restriction endonuclease analysis, we have characterised the molecular defect in 94 patients with thalassaemia major and four with thalassaemia intermedia of Turkish Cypriot descent. We…

Continue ReadingBeta thalassaemia mutations in Turkish Cypriots.