Read more about the article A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.
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A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.

Abstract This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity 2years after radiotherapy. A genome wide association study was performed in 1850 patients from the…

Continue ReadingA genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.
Read more about the article Despeckle Filtering for Multiscale Amplitude-Modulation Frequency-Modulation (AM-FM) Texture Analysis of Ultrasound Images of the Intima-Media Complex.
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Despeckle Filtering for Multiscale Amplitude-Modulation Frequency-Modulation (AM-FM) Texture Analysis of Ultrasound Images of the Intima-Media Complex.

Abstract The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of cardiovascular disease (CVD). Typically, the IMT grows with age and this…

Continue ReadingDespeckle Filtering for Multiscale Amplitude-Modulation Frequency-Modulation (AM-FM) Texture Analysis of Ultrasound Images of the Intima-Media Complex.
Read more about the article The Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis.
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The Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis.

Abstract Epigenetic modifications have proven to play a significant role in cancer development, as well as fetal development. Taking advantage of the knowledge acquired during the last decade, great interest…

Continue ReadingThe Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis.
Read more about the article Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.
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Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.

Abstract There is growing evidence for the involvement of Y-complex nucleoporins (Y-Nups) in cellular processes beyond the inner core of nuclear pores of eukaryotes. To comprehensively assess the range of…

Continue ReadingFunctional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.
Read more about the article An updated overview of HPV-associated head and neck carcinomas.
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An updated overview of HPV-associated head and neck carcinomas.

Abstract Human papilloma virus (HPV)-associated head and neck carcinoma is quite heterogeneous and most of the tumors arise in the oral cavity, oropharynx, hypopharynx and larynx. HPV was just recently…

Continue ReadingAn updated overview of HPV-associated head and neck carcinomas.
Read more about the article Quantitative texture analysis of brain white matter lesions derived from T2-weighted MR images in MS patients with clinically isolated syndrome.
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Quantitative texture analysis of brain white matter lesions derived from T2-weighted MR images in MS patients with clinically isolated syndrome.

Abstract This study investigates the application of texture analysis methods on brain T2-white matter lesions detected with magnetic resonance imaging (MRI) for the prognosis of future disability in subjects diagnosed…

Continue ReadingQuantitative texture analysis of brain white matter lesions derived from T2-weighted MR images in MS patients with clinically isolated syndrome.
Read more about the article Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Abstract The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could…

Continue ReadingGenetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
Read more about the article Genetic epidemiology of cancer predisposition DNA repair genes is probably related with ancestral surviving under adverse environmental conditions.
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Genetic epidemiology of cancer predisposition DNA repair genes is probably related with ancestral surviving under adverse environmental conditions.

Abstract Surviving under a stressful environment may be a real challenge. Individuals (and their offspring) with accumulated genetic variation in their DNA repair genes may have a higher probability to…

Continue ReadingGenetic epidemiology of cancer predisposition DNA repair genes is probably related with ancestral surviving under adverse environmental conditions.
Read more about the article The role of ubiquitin-binding domains in human pathophysiology.
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The role of ubiquitin-binding domains in human pathophysiology.

Abstract Ubiquitination, a fundamental post-translational modification (PTM) resulting in the covalent attachment of ubiquitin (Ub) to a target protein, is currently implicated in several key cellular processes. Although ubiquitination was…

Continue ReadingThe role of ubiquitin-binding domains in human pathophysiology.
Read more about the article Are context-specific measures of parental-reported physical activity and sedentary behaviour associated with accelerometer data in 2-9-year-old European children?
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Are context-specific measures of parental-reported physical activity and sedentary behaviour associated with accelerometer data in 2-9-year-old European children?

Abstract The aim of the present study was to investigate if context-specific measures of parental-reported physical activity and sedentary behaviour are associated with objectively measured physical activity and sedentary time…

Continue ReadingAre context-specific measures of parental-reported physical activity and sedentary behaviour associated with accelerometer data in 2-9-year-old European children?