Read more about the article The Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis.
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The Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis.

Abstract Epigenetic modifications have proven to play a significant role in cancer development, as well as fetal development. Taking advantage of the knowledge acquired during the last decade, great interest…

Continue ReadingThe Epigenome View: An Effort towards Non-Invasive Prenatal Diagnosis.
Read more about the article Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.
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Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.

Abstract There is growing evidence for the involvement of Y-complex nucleoporins (Y-Nups) in cellular processes beyond the inner core of nuclear pores of eukaryotes. To comprehensively assess the range of…

Continue ReadingFunctional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins.
Read more about the article An updated overview of HPV-associated head and neck carcinomas.
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An updated overview of HPV-associated head and neck carcinomas.

Abstract Human papilloma virus (HPV)-associated head and neck carcinoma is quite heterogeneous and most of the tumors arise in the oral cavity, oropharynx, hypopharynx and larynx. HPV was just recently…

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Read more about the article Quantitative texture analysis of brain white matter lesions derived from T2-weighted MR images in MS patients with clinically isolated syndrome.
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Quantitative texture analysis of brain white matter lesions derived from T2-weighted MR images in MS patients with clinically isolated syndrome.

Abstract This study investigates the application of texture analysis methods on brain T2-white matter lesions detected with magnetic resonance imaging (MRI) for the prognosis of future disability in subjects diagnosed…

Continue ReadingQuantitative texture analysis of brain white matter lesions derived from T2-weighted MR images in MS patients with clinically isolated syndrome.
Read more about the article Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Abstract The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could…

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Read more about the article Spectrum of GJB2 mutations in Cypriot nonsyndromic hearing loss subjects.
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Spectrum of GJB2 mutations in Cypriot nonsyndromic hearing loss subjects.

Abstract

Continue ReadingSpectrum of GJB2 mutations in Cypriot nonsyndromic hearing loss subjects.
Read more about the article Manual and automated intima-media thickness and diameter measurements of the common carotid artery in patients with renal failure disease.
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Manual and automated intima-media thickness and diameter measurements of the common carotid artery in patients with renal failure disease.

Abstract The objective of this study was to investigate differences in intima-media thickness (IMT) and diameter (D) measurements of the common carotid artery (CCA) in ultrasound imaging in normal subjects…

Continue ReadingManual and automated intima-media thickness and diameter measurements of the common carotid artery in patients with renal failure disease.
Read more about the article Does the FTO gene interact with the socioeconomic status on the obesity development among young European children? Results from the IDEFICS study.
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Does the FTO gene interact with the socioeconomic status on the obesity development among young European children? Results from the IDEFICS study.

Abstract Various twin studies revealed that the influence of genetic factors on psychological diseases or behaviour is more expressed in socioeconomically advantaged environments. Other studies predominantly show an inverse association…

Continue ReadingDoes the FTO gene interact with the socioeconomic status on the obesity development among young European children? Results from the IDEFICS study.
Read more about the article The mutational spectrum of Lynch syndrome in cyprus.
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The mutational spectrum of Lynch syndrome in cyprus.

Abstract Lynch syndrome is the most common form of hereditary colorectal cancer and is caused by germline mutations in the mismatch repair (MMR) genes MLH1, MSH2, MSH6 and PMS2. Mutation…

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Read more about the article Oligodendrocyte gap junction loss and disconnection from reactive astrocytes in multiple sclerosis gray matter.
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Oligodendrocyte gap junction loss and disconnection from reactive astrocytes in multiple sclerosis gray matter.

Abstract Gap junctions are essential for glial cell function and have been increasingly implicated in multiple sclerosis (MS). Because increasing cortical abnormalities correlate with disease progression and cognitive dysfunction, we…

Continue ReadingOligodendrocyte gap junction loss and disconnection from reactive astrocytes in multiple sclerosis gray matter.