Read more about the article A new DNA polymorphism for prenatal diagnosis of beta-thalassaemia in Mediterranean populations.
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A new DNA polymorphism for prenatal diagnosis of beta-thalassaemia in Mediterranean populations.

Abstract The prevalence of a new polymorphism for the restriction enzyme Ava II in the psi beta-gene of the beta-globin gene cluster was determined in Mediterranean families with at least…

Continue ReadingA new DNA polymorphism for prenatal diagnosis of beta-thalassaemia in Mediterranean populations.
Read more about the article Feasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.
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Feasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.

Abstract The feasibility of using restriction fragment length polymorphisms ( RFLPs ) for the antenatal diagnosis of beta thalassaemia in the U.K.-resident Cypriot and Asian Indian populations has been determined.…

Continue ReadingFeasibility of antenatal diagnosis of beta thalassaemia by DNA polymorphisms in Asian Indian and Cypriot populations.
Read more about the article Association of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.
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Association of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.

Abstract A new polymorphic BgI II restriction endonuclease site in the alpha-globin gene complex has been found in Cypriot, Sardinian, and Greek populations. In all cases, this polymorphism is linked…

Continue ReadingAssociation of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.
Read more about the article Globin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.
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Globin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.

Abstract The genetic factors responsible for the relatively mild clinical phenotypes of some cases of homozygous beta zero thalassaemia (thalassaemia intermedia) in Sardinia have been evaluated. The frequency of deletion…

Continue ReadingGlobin gene mapping studies in Sardinian patients homozygous for beta zero Thalassaemia.
Read more about the article The molecular basis for the clinical diversity of beta thalassaemia in Cypriots.
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The molecular basis for the clinical diversity of beta thalassaemia in Cypriots.

Abstract Much of the clinical variability in the course of homozygous beta thalassaemia in the Cypriot population can be accounted for by the interaction of alpha thalassaemia and by the…

Continue ReadingThe molecular basis for the clinical diversity of beta thalassaemia in Cypriots.
Read more about the article Thalassaemia intermedia in Cyprus: the interaction of alpha and beta thalassaemia.
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Thalassaemia intermedia in Cyprus: the interaction of alpha and beta thalassaemia.

Abstract Restriction endonuclease analysis has been performed on the alpha and beta globin gene clusters of 57 Cypriots homozygous for beta thalassaemia, 30 with the transfusion dependent form of the…

Continue ReadingThalassaemia intermedia in Cyprus: the interaction of alpha and beta thalassaemia.
Read more about the article Hb Summer Hill or alpha 2 beta 2(52)(D3)Asp replaced by His in a Turkish family from Cyprus.
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Hb Summer Hill or alpha 2 beta 2(52)(D3)Asp replaced by His in a Turkish family from Cyprus.

Abstract

Continue ReadingHb Summer Hill or alpha 2 beta 2(52)(D3)Asp replaced by His in a Turkish family from Cyprus.
Read more about the article Alpha-thalassemia in two Mediterranean populations.
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Alpha-thalassemia in two Mediterranean populations.

Abstract We used restriction endonuclease analysis to determine the incidence of alpha-thalassemia in two Mediterranean islands. In a random population sample, the gene frequency of deletion-type alpha-thalassemia-2 (-alpha) was 0.18…

Continue ReadingAlpha-thalassemia in two Mediterranean populations.
Read more about the article Incidence of homozygous beta-thalassaemia in New South Wales, 1961-1976.
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Incidence of homozygous beta-thalassaemia in New South Wales, 1961-1976.

Abstract A case-finding survey yielded 58 persons with transfusion-dependent homozygous beta-thalassaemia who lived either in New South Wales or in the Australian Capital Territory. Of those born between 1961 and…

Continue ReadingIncidence of homozygous beta-thalassaemia in New South Wales, 1961-1976.