Read more about the article Molecular epidemiology of rhinoviruses in Cyprus over three consecutive seasons.
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Molecular epidemiology of rhinoviruses in Cyprus over three consecutive seasons.

Abstract Human rhinoviruses (HRVs) are widespread respiratory pathogens and a major cause of acute respiratory tract infections. The aim of this study was to investigate the molecular epidemiology of rhinovirus…

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Read more about the article Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review).
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Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review).

Abstract Deregulation of cell signaling homeostasis is a predominant feature of cancer initiation and progression. Transforming growth factor β (TGFβ) is a pleiotropic cytokine, which regulates numerous biological processes of…

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Read more about the article Prevalence of overweight and obesity in European children below the age of 10.
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Prevalence of overweight and obesity in European children below the age of 10.

Abstract There is a lack of common surveillance systems providing comparable figures and temporal trends of the prevalence of overweight (OW), obesity and related risk factors among European preschool and…

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Read more about the article Prospective associations between socio-economic status and dietary patterns in European children: the Identification and Prevention of Dietary- and Lifestyle-induced Health Effects in Children and Infants (IDEFICS) Study.
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Prospective associations between socio-economic status and dietary patterns in European children: the Identification and Prevention of Dietary- and Lifestyle-induced Health Effects in Children and Infants (IDEFICS) Study.

Abstract Exploring changes in children's diet over time and the relationship between these changes and socio-economic status (SES) may help to understand the impact of social inequalities on dietary patterns.…

Continue ReadingProspective associations between socio-economic status and dietary patterns in European children: the Identification and Prevention of Dietary- and Lifestyle-induced Health Effects in Children and Infants (IDEFICS) Study.
Read more about the article Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.
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Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.

Abstract Variation in vectorial capacity for human malaria among Anopheles mosquito species is determined by many factors, including behavior, immunity, and life history. To investigate the genomic basis of vectorial…

Continue ReadingMosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.
Read more about the article Phenotypic variability of hyperandrogenemia in females heterozygous for CYP21A2 mutations.
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Phenotypic variability of hyperandrogenemia in females heterozygous for CYP21A2 mutations.

Abstract The objective was to seek evidence on the prevalence and consequences of heterozygous CYP21A2 mutations in girls, adolescent, and adult females with clinical manifestation of androgen excess. The study…

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Read more about the article Transgenic replacement of Cx32 in gap junction-deficient oligodendrocytes rescues the phenotype of a hypomyelinating leukodystrophy model.
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Transgenic replacement of Cx32 in gap junction-deficient oligodendrocytes rescues the phenotype of a hypomyelinating leukodystrophy model.

Abstract Oligodendrocytes are coupled by gap junctions (GJs) formed mainly by connexin47 (Cx47) and Cx32. Recessive GJC2/Cx47 mutations cause Pelizaeus-Merzbacher-like disease, a hypomyelinating leukodystrophy, while GJB1/Cx32 mutations cause neuropathy and…

Continue ReadingTransgenic replacement of Cx32 in gap junction-deficient oligodendrocytes rescues the phenotype of a hypomyelinating leukodystrophy model.
Read more about the article A defence-related Olea europaea β-glucosidase hydrolyses and activates oleuropein into a potent protein cross-linking agent.
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A defence-related Olea europaea β-glucosidase hydrolyses and activates oleuropein into a potent protein cross-linking agent.

Abstract Oleuropein, the major secoiridoid compound in olive, is involved in a sophisticated two-component defence system comprising a β-glucosidase enzyme that activates oleuropein into a toxic glutaraldehyde-like structure. Although oleuropein…

Continue ReadingA defence-related Olea europaea β-glucosidase hydrolyses and activates oleuropein into a potent protein cross-linking agent.
Read more about the article Carcinogenicity of ambient air pollution: use of biomarkers, lessons learnt and future directions.
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Carcinogenicity of ambient air pollution: use of biomarkers, lessons learnt and future directions.

Abstract The association between ambient air pollution (AAP) exposure and lung cancer risk has been investigated in prospective studies and the results are generally consistent, indicating that long-term exposure to…

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Read more about the article Haploinsufficiency of the miR-873/miR-876 microRNA cluster is associated with craniofacial abnormalities.
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Haploinsufficiency of the miR-873/miR-876 microRNA cluster is associated with craniofacial abnormalities.

Abstract MicroRNA haploinsufficiency has been associated with developmental defects in only a limited number of cases. Here we report a de novo genomic microdeletion that includes the LINGO2 gene as…

Continue ReadingHaploinsufficiency of the miR-873/miR-876 microRNA cluster is associated with craniofacial abnormalities.