Read more about the article Oxidative stress in β-thalassaemia and sickle cell disease.
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Oxidative stress in β-thalassaemia and sickle cell disease.

Abstract Sickle cell disease and β-thalassaemia are inherited haemoglobinopathies resulting in structural and quantitative changes in the β-globin chain. These changes lead to instability of the generated haemoglobin or to…

Continue ReadingOxidative stress in β-thalassaemia and sickle cell disease.
Read more about the article Desaturase Activity Is Associated With Weight Status and Metabolic Risk Markers in Young Children.
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Desaturase Activity Is Associated With Weight Status and Metabolic Risk Markers in Young Children.

Abstract Activity of delta-9, delta-6, and delta-5 desaturases (D9D, D6D, D5D) are associated with obesity, insulin resistance, and dyslipidemia. To investigate the association of estimated desaturase activities with weight status,…

Continue ReadingDesaturase Activity Is Associated With Weight Status and Metabolic Risk Markers in Young Children.
Read more about the article Delimiting Species Boundaries within a Paraphyletic Species Complex: Insights from Morphological, Genetic, and Molecular Data on Paramecium sonneborni (Paramecium aurelia species complex, Ciliophora, Protozoa).
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Delimiting Species Boundaries within a Paraphyletic Species Complex: Insights from Morphological, Genetic, and Molecular Data on Paramecium sonneborni (Paramecium aurelia species complex, Ciliophora, Protozoa).

Abstract The demarcation of boundaries between protist species is often problematic because of the absence of a uniform species definition, the abundance of cryptic diversity, and the occurrence of convergent…

Continue ReadingDelimiting Species Boundaries within a Paraphyletic Species Complex: Insights from Morphological, Genetic, and Molecular Data on Paramecium sonneborni (Paramecium aurelia species complex, Ciliophora, Protozoa).
Read more about the article MyoD transcription factor induces myogenesis by inhibiting Twist-1 through miR-206.
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MyoD transcription factor induces myogenesis by inhibiting Twist-1 through miR-206.

Abstract Twist-1 is mostly expressed during development and has been previously shown to control myogenesis. Because its regulation in muscle has not been fully exploited, the aim of this project…

Continue ReadingMyoD transcription factor induces myogenesis by inhibiting Twist-1 through miR-206.
Read more about the article Degradation of 2,4,6-trinitrotoluene by P. aeruginosa and characterization of some metabolites.
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Degradation of 2,4,6-trinitrotoluene by P. aeruginosa and characterization of some metabolites.

Abstract Degradation of 2,4,6-trinitrotoluene (TNT), a nitroaromatic explosive found in the soil and ground water, was investigated using Pseudomonas aeruginosa in in vitro experiments . Biodegradable abilitiy of this bacteria…

Continue ReadingDegradation of 2,4,6-trinitrotoluene by P. aeruginosa and characterization of some metabolites.
Read more about the article Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis.
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Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis.

Abstract Basal-like breast cancer (BLBC) is an aggressive subtype often characterized by distant metastasis, poor patient prognosis, and limited treatment options. Therefore, the discovery of alternative targets to restrain its…

Continue ReadingTargeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis.
Read more about the article Measurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR.
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Measurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR.

Abstract Lentiviruses are the vectors of choice for many preclinical studies and clinical applications of gene therapy. Accurate measurement of biological vector titre before treatment is a prerequisite for vector…

Continue ReadingMeasurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR.
Read more about the article Carriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.
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Carriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.

Abstract Collagen IV nephropathies (COL4Ns) comprise benign familial microscopic hematuria, thin basement membrane nephropathy (TBMN), X-linked Alport syndrome (AS) and also autosomal recessive and dominant AS. Apart from the X-linked…

Continue ReadingCarriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.
Read more about the article Primary resistance to integrase strand-transfer inhibitors in Europe.
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Primary resistance to integrase strand-transfer inhibitors in Europe.

Abstract The objective of this study was to define the natural genotypic variation of the HIV-1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer inhibitor (InSTI) resistance. This…

Continue ReadingPrimary resistance to integrase strand-transfer inhibitors in Europe.
Read more about the article Near East University Genetic Mutation Database (NEU-GD): The first mutation database of Northern Cyprus.
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Near East University Genetic Mutation Database (NEU-GD): The first mutation database of Northern Cyprus.

Abstract The health care system is negatively affected by the genetic disorders that lead to an increasing rate of morbidity and neonatal deaths and affect adults as well. These create…

Continue ReadingNear East University Genetic Mutation Database (NEU-GD): The first mutation database of Northern Cyprus.