Read more about the article Carriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.
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Carriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.

Abstract Collagen IV nephropathies (COL4Ns) comprise benign familial microscopic hematuria, thin basement membrane nephropathy (TBMN), X-linked Alport syndrome (AS) and also autosomal recessive and dominant AS. Apart from the X-linked…

Continue ReadingCarriers of Autosomal Recessive Alport Syndrome with Thin Basement Membrane Nephropathy Presenting as Focal Segmental Glomerulosclerosis in Later Life.
Read more about the article Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFNγ, MMP-2, IGF-II, EGF, TGF-β, IGF-IIR) during pregnancy in the cat uterus.
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Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFNγ, MMP-2, IGF-II, EGF, TGF-β, IGF-IIR) during pregnancy in the cat uterus.

Abstract Early pregnancy is one of the most critical periods of pregnancy, and many factors such as cytokines, enzymes, and members of the immune system have to cooperate in a…

Continue ReadingGene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFNγ, MMP-2, IGF-II, EGF, TGF-β, IGF-IIR) during pregnancy in the cat uterus.
Read more about the article Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.
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Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.

Abstract Two tetrapeptides, HAEE and RADD, which are ionic-complementary to the primary zinc recognition site of amyloid-β (Aβ), have been reported to inhibit zinc-induced dimerization of the Aβ metal-binding domain…

Continue ReadingPeripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.
Read more about the article Hypoxia Is the Driving Force Behind GBM and Could Be a New Tool in GBM Treatment.
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Hypoxia Is the Driving Force Behind GBM and Could Be a New Tool in GBM Treatment.

Abstract Glioblastoma (GBM) can be divided into two distinct disease entities according to the genetic and the epigenetic background of the tumor. Tumor location is associated with high variability in…

Continue ReadingHypoxia Is the Driving Force Behind GBM and Could Be a New Tool in GBM Treatment.
Read more about the article Evolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.
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Evolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.

Abstract Human hGDH2 arose via duplication in the apes and driven by positive selection acquired enhanced catalytic ability under conditions inhibitory to its precursor hGDH1 (common to all mammals). To…

Continue ReadingEvolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.
Read more about the article Glioblastoma Multiforme: The Genetic Perspective of the Treatment Planning.
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Glioblastoma Multiforme: The Genetic Perspective of the Treatment Planning.

Abstract Glioblastoma multiforme (GBM) is divided into two distinct disease entities called primary and secondary GBM. The genetic and the epigenetic background of these tumors are highly variable. These tumors…

Continue ReadingGlioblastoma Multiforme: The Genetic Perspective of the Treatment Planning.
Read more about the article Temporal analysis reveals a key role for VTE5 in vitamin E biosynthesis in olive fruit during on-tree development.
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Temporal analysis reveals a key role for VTE5 in vitamin E biosynthesis in olive fruit during on-tree development.

Abstract The aim of this work was to generate a high resolution temporal mapping of the biosynthetic pathway of vitamin E in olive fruit (Olea europaea cv. "Koroneiki") during 17…

Continue ReadingTemporal analysis reveals a key role for VTE5 in vitamin E biosynthesis in olive fruit during on-tree development.
Read more about the article The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.
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The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.

Abstract The inner ear develops from the otic placode, one of the cranial placodes that arise from a region of ectoderm adjacent to the anterior neural plate called the pre-placodal…

Continue ReadingThe mouse Foxi3 transcription factor is necessary for the development of posterior placodes.
Read more about the article Molecular and Clinical Investigation of Cystinuria in the Greek-Cypriot Population.
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Molecular and Clinical Investigation of Cystinuria in the Greek-Cypriot Population.

Abstract Cystinuria represents 3% of nephrolithiasis in humans. Two genes have been identified as the main genetic causes of cystinuria, SLC3A1 and SLC7A9, with an autosomal recessive mode of inheritance.…

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Read more about the article Adjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch Repair Status of the MOSAIC Study.
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Adjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch Repair Status of the MOSAIC Study.

Abstract The MOSAIC (Multicenter International Study of Oxaliplatin/Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer) study has demonstrated 3-year disease-free survival (DFS) and 6-year overall survival (OS) benefit of adjuvant…

Continue ReadingAdjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch Repair Status of the MOSAIC Study.