Read more about the article Open-Label Fosmetpantotenate, a Phosphopantothenate Replacement Therapy in a Single Patient with Atypical PKAN.
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Open-Label Fosmetpantotenate, a Phosphopantothenate Replacement Therapy in a Single Patient with Atypical PKAN.

Abstract . Pantothenate kinase-associated neurodegeneration (PKAN) is an autosomal recessive disorder with variable onset, rate of progression, and phenotypic expression. Later-onset, more slowly progressive PKAN often presents with neuropsychiatric as…

Continue ReadingOpen-Label Fosmetpantotenate, a Phosphopantothenate Replacement Therapy in a Single Patient with Atypical PKAN.
Read more about the article Familial Resemblance in Dietary Intakes of Children, Adolescents, and Parents: Does Dietary Quality Play a Role?
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Familial Resemblance in Dietary Intakes of Children, Adolescents, and Parents: Does Dietary Quality Play a Role?

Abstract Information on familial resemblance is important for the design of effective family-based interventions. We aimed to quantify familial correlations and estimate the proportion of variation attributable to genetic and…

Continue ReadingFamilial Resemblance in Dietary Intakes of Children, Adolescents, and Parents: Does Dietary Quality Play a Role?
Read more about the article The effect of tomatine on metastasis related matrix metalloproteinase (MMP) activities in breast cancer cell model.
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The effect of tomatine on metastasis related matrix metalloproteinase (MMP) activities in breast cancer cell model.

Abstract Breast cancer is one of the most common malignancies in women and metastasis is the cause of morbidity and mortality in patients. In the development of metastasis, the matrix…

Continue ReadingThe effect of tomatine on metastasis related matrix metalloproteinase (MMP) activities in breast cancer cell model.
Read more about the article Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells.
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Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells.

Abstract Necrosis, apoptosis and autophagic cell death are the main cell death pathways in multicellular organisms, all with distinct and overlapping cellular and biochemical features. DNA damage may trigger different…

Continue ReadingBiphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells.
Read more about the article Cancer incidence and mortality are associated with human development index and health setups in Africa.
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Cancer incidence and mortality are associated with human development index and health setups in Africa.

Abstract This study aimed to analyse the correlation between cancer incidence and mortality and the Human Development Index (HDI) in Africa. Furthermore, to analyse the variations in cancer Mortality to…

Continue ReadingCancer incidence and mortality are associated with human development index and health setups in Africa.
Read more about the article Epidemiology and burden of systemic lupus erythematosus in a Southern European population: data from the community-based lupus registry of Crete, Greece.
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Epidemiology and burden of systemic lupus erythematosus in a Southern European population: data from the community-based lupus registry of Crete, Greece.

Abstract Several population-based studies on systemic lupus erythematosus (SLE) have been reported, yet community-based, individual-case validated, comprehensive reports are missing. We studied the SLE epidemiology and burden on the island…

Continue ReadingEpidemiology and burden of systemic lupus erythematosus in a Southern European population: data from the community-based lupus registry of Crete, Greece.
Read more about the article Functional implications of the utero-placental relaxin (RLN) system in the dog throughout pregnancy and at term.
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Functional implications of the utero-placental relaxin (RLN) system in the dog throughout pregnancy and at term.

Abstract Relaxin (RLN) is a key hormone of pregnancy in mammals best known for its involvement in connective tissue remodeling. In the domestic dog, placental RLN is the only known…

Continue ReadingFunctional implications of the utero-placental relaxin (RLN) system in the dog throughout pregnancy and at term.
Read more about the article Genetics reveal the identity and origin of the lionfish invasion in the Mediterranean Sea.
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Genetics reveal the identity and origin of the lionfish invasion in the Mediterranean Sea.

Abstract Following aquarium releases, invasive lionfishes have colonized large areas of the Caribbean and western Atlantic, resulting in an immense ecological damage. The early stages of that invasion are poorly…

Continue ReadingGenetics reveal the identity and origin of the lionfish invasion in the Mediterranean Sea.
Read more about the article Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species.
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Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species.

Abstract In the dog, there is no luteolysis in the absence of pregnancy. Thus, this species lacks any anti-luteolytic endocrine signal as found in other species that modulate uterine function…

Continue ReadingUterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species.

Combined deficiency of the Cnr1 and Cnr2 receptors protects against age-related bone loss by osteoclast inhibition.

Abstract The endocannabinoid system plays a role in regulating bone mass and bone cell activity and inactivation of the type 1 (Cnr1) or type 2 (Cnr2) cannabinoid receptors influences peak…

Continue ReadingCombined deficiency of the Cnr1 and Cnr2 receptors protects against age-related bone loss by osteoclast inhibition.