Read more about the article Digenic inheritance and genetic modifiers.
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Digenic inheritance and genetic modifiers.

Abstract Digenic inheritance (DI) concerns pathologies with the simplest form of multigenic etiology, implicating more than 1 gene (and perhaps the environment). True DI is when biallelic or even triallelic…

Continue ReadingDigenic inheritance and genetic modifiers.
Read more about the article Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.
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Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.

Abstract Idiopathic Pulmonary Fibrosis (IPF) is a rare disease of the respiratory system in which the lungs stiffen and get scarred, resulting in breathing weakness and eventually leading to death.…

Continue ReadingDrug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.
Read more about the article Restless legs syndrome in adolescents: relationship with sleep quality, cardiorespiratory fitness and body fat.
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Restless legs syndrome in adolescents: relationship with sleep quality, cardiorespiratory fitness and body fat.

Abstract The aim of the current study was to investigate the relationship between restless legs syndrome (RLS) and cardiorespiratory fitness, body composition and sleep quality in a sample of adolescents.…

Continue ReadingRestless legs syndrome in adolescents: relationship with sleep quality, cardiorespiratory fitness and body fat.
Read more about the article Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.
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Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.

Abstract Pediatric cancer survivors are a steadily growing population; however, chronic anthracycline-induced cardiotoxicity (AIC) is a serious long-term complication leading to considerable morbidity. We aimed to identify new genes and…

Continue ReadingExome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.
Read more about the article Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy.
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Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy.

Abstract Penetrance and age of onset of ATTRV30M amyloidotic neuropathy varies significantly among different populations. This variability has been attributed to both genetic and environmental modifiers. We studied the effect…

Continue ReadingGenetic background modifies amyloidosis in a mouse model of ATTR neuropathy.
Read more about the article Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients.
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Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients.

Abstract To examine whether hemodialysis (HD) patients with restless legs syndrome (RLS) are subjects of greater fatigue and impaired quality of life (QoL) compared to HD patients without RLS. Eighty…

Continue ReadingRestless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients.
Read more about the article Deciphering the interplay among genotype, maturity stage and low-temperature storage on phytochemical composition and transcript levels of enzymatic antioxidants in Prunus persica fruit.
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Deciphering the interplay among genotype, maturity stage and low-temperature storage on phytochemical composition and transcript levels of enzymatic antioxidants in Prunus persica fruit.

Abstract The aim of this study was to understand the antioxidant metabolic changes of peach (cvs. 'Royal Glory', 'Red Haven' and 'Sun Cloud') and nectarine fruits (cv. 'Big Top') exposed…

Continue ReadingDeciphering the interplay among genotype, maturity stage and low-temperature storage on phytochemical composition and transcript levels of enzymatic antioxidants in Prunus persica fruit.
Read more about the article Mitochondrial superclusters influence age of onset of Parkinson’s disease in a gender specific manner in the Cypriot population: A case-control study.
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Mitochondrial superclusters influence age of onset of Parkinson’s disease in a gender specific manner in the Cypriot population: A case-control study.

Abstract Despite evidence supporting an involvement of mitochondrial dysfunction in the pathogenesis of some neurodegenerative disorders, there are inconsistent findings concerning mitochondrial haplogroups and their association to neurodegenerative disorders, including…

Continue ReadingMitochondrial superclusters influence age of onset of Parkinson’s disease in a gender specific manner in the Cypriot population: A case-control study.
Read more about the article Editorial.
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Editorial.

Abstract

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Read more about the article New species and new records of ground spiders (Araneae: Gnaphosidae) from Cyprus.
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New species and new records of ground spiders (Araneae: Gnaphosidae) from Cyprus.

Abstract New taxonomic data on the ground spiders of the family Gnaphosidae from the island of Cyprus are presented. Three species are proposed as new to science (Drassyllus cyprius sp.…

Continue ReadingNew species and new records of ground spiders (Araneae: Gnaphosidae) from Cyprus.