Read more about the article Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.
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Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.

Abstract RNA interference (RNAi) is a naturally existing endogenous mechanism for post-transcriptional gene regulation, nowadays commonly utilized for functional characterization of genes and development of potential treatment strategies for diseases.…

Continue ReadingUpdate on the clinical utility of an RNA interference-based treatment: focus on Patisiran.
Read more about the article Distribution and phylogeny of Hyalomma ticks (Acari: Ixodidae) in Turkey.
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Distribution and phylogeny of Hyalomma ticks (Acari: Ixodidae) in Turkey.

Abstract The genus Hyalomma includes some of the most medically and veterinarily important tick species in the world. To clarify and identify the current distribution of the species of Hyalomma,…

Continue ReadingDistribution and phylogeny of Hyalomma ticks (Acari: Ixodidae) in Turkey.

Vascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia.

Abstract Familial dyslipidemias of either heterozygous (heFH) or combined (FCH) type lead to accelerated atherogenesis and increased cardiovascular risk. The aim of this study was to investigate in statin-naïve adult…

Continue ReadingVascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia.
Read more about the article Long-read genome sequence assembly provides insight into ongoing retroviral invasion of the koala germline.
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Long-read genome sequence assembly provides insight into ongoing retroviral invasion of the koala germline.

Abstract The koala retrovirus (KoRV) is implicated in several diseases affecting the koala (Phascolarctos cinereus). KoRV provirus can be present in the genome of koalas as an endogenous retrovirus (present…

Continue ReadingLong-read genome sequence assembly provides insight into ongoing retroviral invasion of the koala germline.
Read more about the article Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.
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Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.

Abstract Anorexia nervosa (AN) is a complex neuropsychiatric disorder presenting with dangerously low body weight, and a deep and persistent fear of gaining weight. To date, only one genome-wide significant…

Continue ReadingInvestigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.
Read more about the article Legislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape.
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Legislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape.

Abstract Despite the increasing availability of direct-to-consumer (DTC) genetic testing, it is currently unclear how such services are regulated in Europe, due to the lack of EU or national legislation…

Continue ReadingLegislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape.
Read more about the article Monumental olive trees of Cyprus contributed to the establishment of the contemporary olive germplasm.
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Monumental olive trees of Cyprus contributed to the establishment of the contemporary olive germplasm.

Abstract Even though Cyprus was an important crossing point for the westward spread of olive, and one of the primary regions of domestication, its genetic recourses remain uncharted at a…

Continue ReadingMonumental olive trees of Cyprus contributed to the establishment of the contemporary olive germplasm.
Read more about the article Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].
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Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

Abstract

Continue ReadingCorrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].
Read more about the article – a novel candidate breast cancer susceptibility locus on 6q14.1.
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– a novel candidate breast cancer susceptibility locus on 6q14.1.

Abstract Most non- breast cancer families have no identified genetic cause. We used linkage and haplotype analyses in familial and sporadic breast cancer cases to identify a susceptibility locus on…

Continue Reading– a novel candidate breast cancer susceptibility locus on 6q14.1.
Read more about the article Effects of controlled dehydration on sleep quality and quantity: A polysomnographic study in healthy young adults.
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Effects of controlled dehydration on sleep quality and quantity: A polysomnographic study in healthy young adults.

Abstract Dehydration is associated with several alternations in body homeostasis involving both physiological and mental aspects. In addition some studies have reported a negative effect of dehydration on subjectively assessed…

Continue ReadingEffects of controlled dehydration on sleep quality and quantity: A polysomnographic study in healthy young adults.