Read more about the article Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Abstract Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from…

Continue ReadingProtein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Read more about the article Paediatric departments need to improve residents’ training in adolescent medicine and health: a position paper of the European Academy of Paediatrics.
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Paediatric departments need to improve residents’ training in adolescent medicine and health: a position paper of the European Academy of Paediatrics.

Abstract In many European countries, paediatric junior staff has no formal training in adolescent medicine and is ill-equipped to deal with issues and health problems such as substance use, unprotected…

Continue ReadingPaediatric departments need to improve residents’ training in adolescent medicine and health: a position paper of the European Academy of Paediatrics.
Read more about the article The Association Between APOA5 Gene Polymorphisms and Plasma Lipids in the Turkish Cypriot Population: A Possible Biomarker for Preventing Cardiovascular Diseases.
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The Association Between APOA5 Gene Polymorphisms and Plasma Lipids in the Turkish Cypriot Population: A Possible Biomarker for Preventing Cardiovascular Diseases.

Abstract Apolipoprotein A5 (APOA5 or APO A-V) polymorphisms have long been reported to be associated with cardiovascular disease and plasma lipid levels. The present study was undertaken to investigate the…

Continue ReadingThe Association Between APOA5 Gene Polymorphisms and Plasma Lipids in the Turkish Cypriot Population: A Possible Biomarker for Preventing Cardiovascular Diseases.
Read more about the article – a novel candidate breast cancer susceptibility locus on 6q14.1.
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– a novel candidate breast cancer susceptibility locus on 6q14.1.

Abstract Most non- breast cancer families have no identified genetic cause. We used linkage and haplotype analyses in familial and sporadic breast cancer cases to identify a susceptibility locus on…

Continue Reading– a novel candidate breast cancer susceptibility locus on 6q14.1.
Read more about the article Effects of controlled dehydration on sleep quality and quantity: A polysomnographic study in healthy young adults.
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Effects of controlled dehydration on sleep quality and quantity: A polysomnographic study in healthy young adults.

Abstract Dehydration is associated with several alternations in body homeostasis involving both physiological and mental aspects. In addition some studies have reported a negative effect of dehydration on subjectively assessed…

Continue ReadingEffects of controlled dehydration on sleep quality and quantity: A polysomnographic study in healthy young adults.
Read more about the article Omega-3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model.
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Omega-3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model.

Abstract The purpose of this study was to evaluate the neuroprotective effects of omega-3 polyunsaturated fatty acid (ω3-PUFA) supplementation, alone or in combination with timolol eye drops, in a mouse…

Continue ReadingOmega-3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model.
Read more about the article Restless legs syndrome in Multiple Sclerosis patients: a contributing factor for fatigue, impaired functional capacity, and diminished health-related quality of life.
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Restless legs syndrome in Multiple Sclerosis patients: a contributing factor for fatigue, impaired functional capacity, and diminished health-related quality of life.

Abstract Objectives Restless legs syndrome (RLS) symptoms are common in Multiple Sclerosis (MS) patients. The aim of the current study was to examine for the first time whether RLS could…

Continue ReadingRestless legs syndrome in Multiple Sclerosis patients: a contributing factor for fatigue, impaired functional capacity, and diminished health-related quality of life.
Read more about the article PTTG-1 (Securin) immunoexpression in meningiomas correlates with tumor grade and proliferation rate: potential use as a diagnostic marker of malignancy.
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PTTG-1 (Securin) immunoexpression in meningiomas correlates with tumor grade and proliferation rate: potential use as a diagnostic marker of malignancy.

Abstract This study essentially aims to contribute to the immunohistochemical investigation of the use of pituitary tumor transforming gene (PTTG) as a marker of cell proliferation or advanced tumor grade…

Continue ReadingPTTG-1 (Securin) immunoexpression in meningiomas correlates with tumor grade and proliferation rate: potential use as a diagnostic marker of malignancy.
Read more about the article Dysosteosclerosis is also caused by TNFRSF11A mutation.
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Dysosteosclerosis is also caused by TNFRSF11A mutation.

Abstract Dysosteosclerosis (DOS) is a form of sclerosing bone disease characterized by irregular osteosclerosis and platyspondyly. Its mode of inheritance is autosomal recessive. SLC29A3 mutations have been reported as the…

Continue ReadingDysosteosclerosis is also caused by TNFRSF11A mutation.
Read more about the article Integrating multi-source information on a single network to detect disease-related clusters of molecular mechanisms.
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Integrating multi-source information on a single network to detect disease-related clusters of molecular mechanisms.

Abstract The abundance of available information for each disease from multiple sources (e.g. as genetic, regulatory, metabolic, and protein-protein interaction) constitutes both an advantage and a challenge in identifying disease-specific…

Continue ReadingIntegrating multi-source information on a single network to detect disease-related clusters of molecular mechanisms.