Read more about the article Genetic characterisation of 19 autosomal STR loci in a population sample from the Southeastern Anatolia Region of Turkey.
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Genetic characterisation of 19 autosomal STR loci in a population sample from the Southeastern Anatolia Region of Turkey.

Abstract Southeastern Anatolia is the smallest, yet the most densely populated region among the seven major geographic constituents of Turkey. Situated in the Upper Mesopotamia, Southeastern Anatolia was also the…

Continue ReadingGenetic characterisation of 19 autosomal STR loci in a population sample from the Southeastern Anatolia Region of Turkey.
Read more about the article Genetic diversity of Avena ventricosa populations along an ecogeographical transect in Cyprus is correlated to environmental variables.
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Genetic diversity of Avena ventricosa populations along an ecogeographical transect in Cyprus is correlated to environmental variables.

Abstract Avena ventricosa Balansa ex Coss. is considered the C-genome donor of the cultivated hexaploid oat and is a 'priority' species for conservation, since it has limited geographic distribution and…

Continue ReadingGenetic diversity of Avena ventricosa populations along an ecogeographical transect in Cyprus is correlated to environmental variables.
Read more about the article Selection and Identification of Skeletal-Muscle-Targeted RNA Aptamers.
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Selection and Identification of Skeletal-Muscle-Targeted RNA Aptamers.

Abstract Oligonucleotide gene therapy has shown great promise for the treatment of muscular dystrophies. Nevertheless, the selective delivery to affected muscles has shown to be challenging because of their high…

Continue ReadingSelection and Identification of Skeletal-Muscle-Targeted RNA Aptamers.
Read more about the article Monitoring opioid and benzodiazepine use and abuse: Is oral fluid or urine the preferred specimen type?
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Monitoring opioid and benzodiazepine use and abuse: Is oral fluid or urine the preferred specimen type?

Abstract Oral fluid (OF) has become an increasingly popular matrix to assess compliance in pain management and addiction settings as it reduces the likelihood of adulteration. However, drug concentrations and…

Continue ReadingMonitoring opioid and benzodiazepine use and abuse: Is oral fluid or urine the preferred specimen type?
Read more about the article Combined effect of glutamine at position 70 of HLA-DRB1 and alanine at position 57 of HLA-DQB1 in type 1 diabetes: An epitope analysis.
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Combined effect of glutamine at position 70 of HLA-DRB1 and alanine at position 57 of HLA-DQB1 in type 1 diabetes: An epitope analysis.

Abstract The contribution of specific HLA Class II alleles in type 1 diabetes is determined by polymorphic amino acid epitopes that direct antigen binding therefore, along with conventional allele frequency…

Continue ReadingCombined effect of glutamine at position 70 of HLA-DRB1 and alanine at position 57 of HLA-DQB1 in type 1 diabetes: An epitope analysis.
Read more about the article Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion.
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Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion.

Abstract Tumor microenvironment consists of the extracellular matrix (ECM), stromal cells, such as fibroblasts (FBs) and cancer associated fibroblasts (CAFs), and a myriad of soluble factors. In many tumor types,…

Continue ReadingTransforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion.
Read more about the article Intrathecal gene therapy in mouse models expressing CMT1X mutations.
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Intrathecal gene therapy in mouse models expressing CMT1X mutations.

Abstract Gap junction beta-1 (GJB1) gene mutations affecting the gap junction protein connexin32 (Cx32) cause the X-linked Charcot-Marie-Tooth disease (CMT1X), a common inherited neuropathy. Targeted expression of virally delivered Cx32…

Continue ReadingIntrathecal gene therapy in mouse models expressing CMT1X mutations.
Read more about the article The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.
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The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.

Abstract Although the spliceogenic nature of the BRCA2 c.68-7T > A variant has been demonstrated, its association with cancer risk remains controversial. In this study, we accurately quantified by real-time PCR and…

Continue ReadingThe BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.
Read more about the article Improving ancestry distinctions among Southwest Asian populations.
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Improving ancestry distinctions among Southwest Asian populations.

Abstract The Kidd Lab panel of 55 AISNPs can provide up to 10 statistically relevant biogeographic groupings of a global set of populations. A second-tier panel would be useful for…

Continue ReadingImproving ancestry distinctions among Southwest Asian populations.
Read more about the article Food and beverage intakes according to physical activity levels in European children: the IDEFICS (Identification and prevention of Dietary and lifestyle induced health EFfects In Children and infantS) study.
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Food and beverage intakes according to physical activity levels in European children: the IDEFICS (Identification and prevention of Dietary and lifestyle induced health EFfects In Children and infantS) study.

Abstract Physical activity (PA) levels and dietary habits are considered some of the most important factors associated with obesity. The present study aimed to examine the association between PA level…

Continue ReadingFood and beverage intakes according to physical activity levels in European children: the IDEFICS (Identification and prevention of Dietary and lifestyle induced health EFfects In Children and infantS) study.