Read more about the article Combination of 247 Genome-Wide Association Studies Reveals High Cancer Risk as a Result of Evolutionary Adaptation.
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Combination of 247 Genome-Wide Association Studies Reveals High Cancer Risk as a Result of Evolutionary Adaptation.

Abstract Analysis of GLOBOCAN-2012 data shows clearly here that cancer incidence worldwide is highly related with low average annual temperatures and extreme low temperatures. This applies for all cancers together…

Continue ReadingCombination of 247 Genome-Wide Association Studies Reveals High Cancer Risk as a Result of Evolutionary Adaptation.
Read more about the article Chloro(triphenylphosphine)gold(I) a forefront reagent in gold chemistry as apoptotic agent for cancer cells.
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Chloro(triphenylphosphine)gold(I) a forefront reagent in gold chemistry as apoptotic agent for cancer cells.

Abstract The antiproliferative activity of the gold complex [Au(tpp)Cl] (1) (tpp=triphenyphosphine) against human breast adenocarcinoma cells (MCF-7) and normal human fetal lung fibroblast cells (MRC-5) was investigated. The compound exhibits…

Continue ReadingChloro(triphenylphosphine)gold(I) a forefront reagent in gold chemistry as apoptotic agent for cancer cells.
Read more about the article Modeling Mesenchymal Stem Cells in TMJ Rheumatoid Arthritis and Osteoarthritis Therapy.
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Modeling Mesenchymal Stem Cells in TMJ Rheumatoid Arthritis and Osteoarthritis Therapy.

Abstract Stem cells have self-renewal capacity and an ability to differentiate into particular cell types generating mature cells. Mesenchymal stem cells (MSCs) have a significant role in tissue homeostasis, which…

Continue ReadingModeling Mesenchymal Stem Cells in TMJ Rheumatoid Arthritis and Osteoarthritis Therapy.
Read more about the article International External Validation Study of the 2014 European Society of Cardiology Guidelines on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (EVIDENCE-HCM).
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International External Validation Study of the 2014 European Society of Cardiology Guidelines on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (EVIDENCE-HCM).

Abstract Identification of people with hypertrophic cardiomyopathy (HCM) who are at risk of sudden cardiac death (SCD) and require a prophylactic implantable cardioverter defibrillator is challenging. In 2014, the European…

Continue ReadingInternational External Validation Study of the 2014 European Society of Cardiology Guidelines on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (EVIDENCE-HCM).
Read more about the article Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.
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Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.

Abstract RNA interference (RNAi) is a naturally existing endogenous mechanism for post-transcriptional gene regulation, nowadays commonly utilized for functional characterization of genes and development of potential treatment strategies for diseases.…

Continue ReadingUpdate on the clinical utility of an RNA interference-based treatment: focus on Patisiran.
Read more about the article Distribution and phylogeny of Hyalomma ticks (Acari: Ixodidae) in Turkey.
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Distribution and phylogeny of Hyalomma ticks (Acari: Ixodidae) in Turkey.

Abstract The genus Hyalomma includes some of the most medically and veterinarily important tick species in the world. To clarify and identify the current distribution of the species of Hyalomma,…

Continue ReadingDistribution and phylogeny of Hyalomma ticks (Acari: Ixodidae) in Turkey.

Vascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia.

Abstract Familial dyslipidemias of either heterozygous (heFH) or combined (FCH) type lead to accelerated atherogenesis and increased cardiovascular risk. The aim of this study was to investigate in statin-naïve adult…

Continue ReadingVascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia.
Read more about the article Long-read genome sequence assembly provides insight into ongoing retroviral invasion of the koala germline.
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Long-read genome sequence assembly provides insight into ongoing retroviral invasion of the koala germline.

Abstract The koala retrovirus (KoRV) is implicated in several diseases affecting the koala (Phascolarctos cinereus). KoRV provirus can be present in the genome of koalas as an endogenous retrovirus (present…

Continue ReadingLong-read genome sequence assembly provides insight into ongoing retroviral invasion of the koala germline.
Read more about the article Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.
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Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.

Abstract Anorexia nervosa (AN) is a complex neuropsychiatric disorder presenting with dangerously low body weight, and a deep and persistent fear of gaining weight. To date, only one genome-wide significant…

Continue ReadingInvestigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.
Read more about the article Legislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape.
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Legislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape.

Abstract Despite the increasing availability of direct-to-consumer (DTC) genetic testing, it is currently unclear how such services are regulated in Europe, due to the lack of EU or national legislation…

Continue ReadingLegislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape.