Read more about the article Impact of Genetic Defects on Coronary Atherosclerosis among Turkish Cypriots.
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Impact of Genetic Defects on Coronary Atherosclerosis among Turkish Cypriots.

Abstract The distribution of gene variants in the Turkish Cypriot population with coronary artery disease has not been investigated. In this study, we sought to research different genetic variants in…

Continue ReadingImpact of Genetic Defects on Coronary Atherosclerosis among Turkish Cypriots.
Read more about the article New species and new records of ground spiders (Araneae: Gnaphosidae) from Cyprus.
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New species and new records of ground spiders (Araneae: Gnaphosidae) from Cyprus.

Abstract New taxonomic data on the ground spiders of the family Gnaphosidae from the island of Cyprus are presented. Three species are proposed as new to science (Drassyllus cyprius sp.…

Continue ReadingNew species and new records of ground spiders (Araneae: Gnaphosidae) from Cyprus.
Read more about the article Smartphone Applications for Educating and Helping Non-motivating Patients Adhere to Medication That Treats Mental Health Conditions: Aims and Functioning.
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Smartphone Applications for Educating and Helping Non-motivating Patients Adhere to Medication That Treats Mental Health Conditions: Aims and Functioning.

Abstract Patients prescribed with medication that treats mental health conditions benefit the most compared to those prescribed with other types of medication. However, they are also the most difficult to…

Continue ReadingSmartphone Applications for Educating and Helping Non-motivating Patients Adhere to Medication That Treats Mental Health Conditions: Aims and Functioning.
Read more about the article Combination of 247 Genome-Wide Association Studies Reveals High Cancer Risk as a Result of Evolutionary Adaptation.
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Combination of 247 Genome-Wide Association Studies Reveals High Cancer Risk as a Result of Evolutionary Adaptation.

Abstract Analysis of GLOBOCAN-2012 data shows clearly here that cancer incidence worldwide is highly related with low average annual temperatures and extreme low temperatures. This applies for all cancers together…

Continue ReadingCombination of 247 Genome-Wide Association Studies Reveals High Cancer Risk as a Result of Evolutionary Adaptation.
Read more about the article Association analysis identifies 65 new breast cancer risk loci.
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Association analysis identifies 65 new breast cancer risk loci.

Abstract Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast…

Continue ReadingAssociation analysis identifies 65 new breast cancer risk loci.
Read more about the article Chloro(triphenylphosphine)gold(I) a forefront reagent in gold chemistry as apoptotic agent for cancer cells.
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Chloro(triphenylphosphine)gold(I) a forefront reagent in gold chemistry as apoptotic agent for cancer cells.

Abstract The antiproliferative activity of the gold complex [Au(tpp)Cl] (1) (tpp=triphenyphosphine) against human breast adenocarcinoma cells (MCF-7) and normal human fetal lung fibroblast cells (MRC-5) was investigated. The compound exhibits…

Continue ReadingChloro(triphenylphosphine)gold(I) a forefront reagent in gold chemistry as apoptotic agent for cancer cells.
Read more about the article Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Abstract Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease. We conducted a GWAS using 21,468 ER-negative cases and…

Continue ReadingIdentification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
Read more about the article Modeling Mesenchymal Stem Cells in TMJ Rheumatoid Arthritis and Osteoarthritis Therapy.
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Modeling Mesenchymal Stem Cells in TMJ Rheumatoid Arthritis and Osteoarthritis Therapy.

Abstract Stem cells have self-renewal capacity and an ability to differentiate into particular cell types generating mature cells. Mesenchymal stem cells (MSCs) have a significant role in tissue homeostasis, which…

Continue ReadingModeling Mesenchymal Stem Cells in TMJ Rheumatoid Arthritis and Osteoarthritis Therapy.
Read more about the article International External Validation Study of the 2014 European Society of Cardiology Guidelines on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (EVIDENCE-HCM).
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International External Validation Study of the 2014 European Society of Cardiology Guidelines on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (EVIDENCE-HCM).

Abstract Identification of people with hypertrophic cardiomyopathy (HCM) who are at risk of sudden cardiac death (SCD) and require a prophylactic implantable cardioverter defibrillator is challenging. In 2014, the European…

Continue ReadingInternational External Validation Study of the 2014 European Society of Cardiology Guidelines on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (EVIDENCE-HCM).
Read more about the article Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.
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Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.

Abstract RNA interference (RNAi) is a naturally existing endogenous mechanism for post-transcriptional gene regulation, nowadays commonly utilized for functional characterization of genes and development of potential treatment strategies for diseases.…

Continue ReadingUpdate on the clinical utility of an RNA interference-based treatment: focus on Patisiran.