Read more about the article Neuronal Expression of Truncated Tau Efficiently Promotes Neurodegeneration in Animal Models: Pitfalls of Toxic Oligomer Analysis.
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Neuronal Expression of Truncated Tau Efficiently Promotes Neurodegeneration in Animal Models: Pitfalls of Toxic Oligomer Analysis.

Abstract Animal models of neurodegeneration induced by neuronal expression of truncated tau protein emerge as an important tool for understanding the pathogenesis of human tauopathies and for therapy development. Here…

Continue ReadingNeuronal Expression of Truncated Tau Efficiently Promotes Neurodegeneration in Animal Models: Pitfalls of Toxic Oligomer Analysis.
Read more about the article PRACTICE OF CONSANGUINITY AND ATTITUDES TOWARDS RISK IN THE PASHTUN POPULATION OF KHYBER PAKHTUNKHWA, PAKISTAN.
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PRACTICE OF CONSANGUINITY AND ATTITUDES TOWARDS RISK IN THE PASHTUN POPULATION OF KHYBER PAKHTUNKHWA, PAKISTAN.

Abstract SummaryThis study aimed to investigate the frequency of consanguineous marriages and level of understanding of consanguinity-associated genetic risks in the Pashtun population, Pakistan. Information was gathered using a detailed…

Continue ReadingPRACTICE OF CONSANGUINITY AND ATTITUDES TOWARDS RISK IN THE PASHTUN POPULATION OF KHYBER PAKHTUNKHWA, PAKISTAN.
Read more about the article Nipple aspirate fluid-A liquid biopsy for diagnosing breast health.
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Nipple aspirate fluid-A liquid biopsy for diagnosing breast health.

Abstract Nipple secretions are protein-rich and a potential source of breast cancer biomarkers for breast cancer screening. Previous studies of specific proteins have shown limited correlation with clinicopathological features. Our…

Continue ReadingNipple aspirate fluid-A liquid biopsy for diagnosing breast health.
Read more about the article Variations in the 3’UTR of the Gene in Heterozygous Females with Hyperandrogenaemia.
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Variations in the 3’UTR of the Gene in Heterozygous Females with Hyperandrogenaemia.

Abstract Heterozygosity for mutations in females is possibly related to increased risk of developing clinical hyperandrogenism. The present study was designed to seek evidence on the phenotype-genotype correlation in female…

Continue ReadingVariations in the 3’UTR of the Gene in Heterozygous Females with Hyperandrogenaemia.
Read more about the article Successful use of tocilizumab in two cases of severe autoinflammatory disease with a single copy of the Mediterranean fever gene.
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Successful use of tocilizumab in two cases of severe autoinflammatory disease with a single copy of the Mediterranean fever gene.

Abstract

Continue ReadingSuccessful use of tocilizumab in two cases of severe autoinflammatory disease with a single copy of the Mediterranean fever gene.
Read more about the article Familial Resemblance in Dietary Intakes of Children, Adolescents, and Parents: Does Dietary Quality Play a Role?
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Familial Resemblance in Dietary Intakes of Children, Adolescents, and Parents: Does Dietary Quality Play a Role?

Abstract Information on familial resemblance is important for the design of effective family-based interventions. We aimed to quantify familial correlations and estimate the proportion of variation attributable to genetic and…

Continue ReadingFamilial Resemblance in Dietary Intakes of Children, Adolescents, and Parents: Does Dietary Quality Play a Role?
Read more about the article Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells.
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Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells.

Abstract Necrosis, apoptosis and autophagic cell death are the main cell death pathways in multicellular organisms, all with distinct and overlapping cellular and biochemical features. DNA damage may trigger different…

Continue ReadingBiphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells.
Read more about the article Epidemiology and burden of systemic lupus erythematosus in a Southern European population: data from the community-based lupus registry of Crete, Greece.
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Epidemiology and burden of systemic lupus erythematosus in a Southern European population: data from the community-based lupus registry of Crete, Greece.

Abstract Several population-based studies on systemic lupus erythematosus (SLE) have been reported, yet community-based, individual-case validated, comprehensive reports are missing. We studied the SLE epidemiology and burden on the island…

Continue ReadingEpidemiology and burden of systemic lupus erythematosus in a Southern European population: data from the community-based lupus registry of Crete, Greece.
Read more about the article Genetics reveal the identity and origin of the lionfish invasion in the Mediterranean Sea.
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Genetics reveal the identity and origin of the lionfish invasion in the Mediterranean Sea.

Abstract Following aquarium releases, invasive lionfishes have colonized large areas of the Caribbean and western Atlantic, resulting in an immense ecological damage. The early stages of that invasion are poorly…

Continue ReadingGenetics reveal the identity and origin of the lionfish invasion in the Mediterranean Sea.

Combined deficiency of the Cnr1 and Cnr2 receptors protects against age-related bone loss by osteoclast inhibition.

Abstract The endocannabinoid system plays a role in regulating bone mass and bone cell activity and inactivation of the type 1 (Cnr1) or type 2 (Cnr2) cannabinoid receptors influences peak…

Continue ReadingCombined deficiency of the Cnr1 and Cnr2 receptors protects against age-related bone loss by osteoclast inhibition.