Read more about the article A new public health genomics model for common complex diseases, with an application to common behavioral disorders.
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A new public health genomics model for common complex diseases, with an application to common behavioral disorders.

Abstract In the light of common forms of gene-environment interplay, particularly epigenomics and ecogenetics, the incorporation of envirome data into public health genomics models becomes necessary. Developing and restructuring public…

Continue ReadingA new public health genomics model for common complex diseases, with an application to common behavioral disorders.
Read more about the article LaTcOm: a web server for visualizing rare codon clusters in coding sequences.
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LaTcOm: a web server for visualizing rare codon clusters in coding sequences.

Abstract We present LaTcOm, a new web tool, which offers several alternative methods for 'rare codon cluster' (RCC) identification from a single and simple graphical user interface. In the current…

Continue ReadingLaTcOm: a web server for visualizing rare codon clusters in coding sequences.
Read more about the article A comparison between disposable and reusable single fiber needle electrodes in relation to stimulated single fiber studies.
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A comparison between disposable and reusable single fiber needle electrodes in relation to stimulated single fiber studies.

Abstract To compare disposable and reusable single fiber needle recordings in relation to stimulated single fiber studies. At least 10 potentials were sampled using each needle type from each patient…

Continue ReadingA comparison between disposable and reusable single fiber needle electrodes in relation to stimulated single fiber studies.
Read more about the article Endogenous TWIST expression and differentiation are opposite during human muscle development.
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Endogenous TWIST expression and differentiation are opposite during human muscle development.

Abstract TWIST is a transcription factor expressed during early embryonic development. In this study we investigate the expression of TWIST during human muscle development. Human TWIST was found to be…

Continue ReadingEndogenous TWIST expression and differentiation are opposite during human muscle development.
Read more about the article Significant enrichment of Y-bearing chromosome human spermatozoa using a modified centrifugation technique.
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Significant enrichment of Y-bearing chromosome human spermatozoa using a modified centrifugation technique.

Abstract The effective separation of X- and Y-bearing chromosome spermatozoa has been a topic of major attraction to a number of scientific disciplines. Approaches have typically been based upon either…

Continue ReadingSignificant enrichment of Y-bearing chromosome human spermatozoa using a modified centrifugation technique.
Read more about the article Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos.
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Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos.

Abstract The Focal Adhesion Kinase is a well studied tyrosine kinase involved in a wide number of cellular processes including cell adhesion and migration. It has also been shown to…

Continue ReadingActivation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos.
Read more about the article Generation of a selectively cytotoxic fusion protein against p53 mutated cancers.
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Generation of a selectively cytotoxic fusion protein against p53 mutated cancers.

Abstract A significant number of cancers are caused by defects in p21 causing functional defects in p21 or p53 tumour-suppressor proteins. This has led to many therapeutic approaches including restoration…

Continue ReadingGeneration of a selectively cytotoxic fusion protein against p53 mutated cancers.
Read more about the article Overview of genetic defects in endocrinopathies in the island of Cyprus; evidence of a founder effect.
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Overview of genetic defects in endocrinopathies in the island of Cyprus; evidence of a founder effect.

Abstract Hereditary endocrinopathies in Cyprus exhibit evidence of a founder effect and display the influence of past migration patterns. The genetic frequency and mutation pattern of a specific disorder of…

Continue ReadingOverview of genetic defects in endocrinopathies in the island of Cyprus; evidence of a founder effect.
Read more about the article MeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21.
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MeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21.

Abstract To reevaluate the efficiency of the 12 differentially methylated regions (DMRs) used in the methylated DNA immunoprecipitation (MeDIP) real-time quantitative polymerase chain reaction (real-time qPCR) based approach, develop an…

Continue ReadingMeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21.