Read more about the article Reconstruction of paternal genotypes over multiple breeding seasons reveals male green turtles do not breed annually.
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Reconstruction of paternal genotypes over multiple breeding seasons reveals male green turtles do not breed annually.

Abstract For species of conservation concern, knowledge of key life-history and demographic components, such as the number and sex ratio of breeding adults, is essential for accurate assessments of population…

Continue ReadingReconstruction of paternal genotypes over multiple breeding seasons reveals male green turtles do not breed annually.
Read more about the article Geographical distribution of plakophilin-2 mutation prevalence in patients with arrhythmogenic cardiomyopathy.
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Geographical distribution of plakophilin-2 mutation prevalence in patients with arrhythmogenic cardiomyopathy.

Abstract Arrhythmogenic cardiomyopathy (AC) is characterised by myocardial fibrofatty tissue infiltration and presents with palpitations, ventricular arrhythmias, syncope and sudden cardiac death. AC is associated with mutations in genes encoding…

Continue ReadingGeographical distribution of plakophilin-2 mutation prevalence in patients with arrhythmogenic cardiomyopathy.
Read more about the article A new non-invasive prenatal diagnosis of Down syndrome through epigenetic markers and real-time qPCR.
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A new non-invasive prenatal diagnosis of Down syndrome through epigenetic markers and real-time qPCR.

Abstract Non-invasive prenatal diagnosis (NIPD) of Down syndrome is rapidly evolving. Currently, two applications for NIPD of Down syndrome have been developed with potential and have displayed positive results; the…

Continue ReadingA new non-invasive prenatal diagnosis of Down syndrome through epigenetic markers and real-time qPCR.
Read more about the article Gap junction pathology in multiple sclerosis lesions and normal-appearing white matter.
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Gap junction pathology in multiple sclerosis lesions and normal-appearing white matter.

Abstract Oligodendrocyte gap junctions (GJs) are vital for central nervous system myelination, but their involvement in multiple sclerosis (MS) pathology remains unknown. The aim of this study was to examine…

Continue ReadingGap junction pathology in multiple sclerosis lesions and normal-appearing white matter.
Read more about the article Disruption of oligodendrocyte gap junctions in experimental autoimmune encephalomyelitis.
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Disruption of oligodendrocyte gap junctions in experimental autoimmune encephalomyelitis.

Abstract Gap junctions (GJs) are vital for oligodendrocyte survival and myelination. In order to examine how different stages of inflammatory demyelination affect oligodendrocyte GJs, we studied the expression of oligodendrocytic…

Continue ReadingDisruption of oligodendrocyte gap junctions in experimental autoimmune encephalomyelitis.
Read more about the article Maternal plasma sequencing: a powerful tool towards fetal whole genome recovery.
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Maternal plasma sequencing: a powerful tool towards fetal whole genome recovery.

Abstract Noninvasive prenatal diagnosis of chromosomal aneuploidies, although challenging, has been achieved through the implementation of novel methodologies such as methylated DNA immunoprecipitation and next generation sequencing technologies. Nevertheless, additional…

Continue ReadingMaternal plasma sequencing: a powerful tool towards fetal whole genome recovery.
Read more about the article A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis.
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A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis.

Abstract The unfolded protein response (UPR) is a major signalling cascade acting in the quality control of protein folding in the endoplasmic reticulum (ER). The cascade is known to play…

Continue ReadingA mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis.
Read more about the article The homeobox transcription factor cut coordinates patterning and growth during Drosophila airway remodeling.
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The homeobox transcription factor cut coordinates patterning and growth during Drosophila airway remodeling.

Abstract A fundamental question in developmental biology is how tissue growth and patterning are coordinately regulated to generate complex organs with characteristic shapes and sizes. We showed that in the…

Continue ReadingThe homeobox transcription factor cut coordinates patterning and growth during Drosophila airway remodeling.
Read more about the article C3 glomerulonephritis/CFHR5 nephropathy is an endemic disease in Cyprus: clinical and molecular findings in 21 families.
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C3 glomerulonephritis/CFHR5 nephropathy is an endemic disease in Cyprus: clinical and molecular findings in 21 families.

Abstract Microscopic haematuria is the presenting symptom of several conditions, either heritable or acquired. A well-recognized familial condition is Alport syndrome, either of X-linked or autosomal recessive inheritance, as well…

Continue ReadingC3 glomerulonephritis/CFHR5 nephropathy is an endemic disease in Cyprus: clinical and molecular findings in 21 families.
Read more about the article The complex history of the olive tree: from Late Quaternary diversification of Mediterranean lineages to primary domestication in the northern Levant.
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The complex history of the olive tree: from Late Quaternary diversification of Mediterranean lineages to primary domestication in the northern Levant.

Abstract The location and timing of domestication of the olive tree, a key crop in Early Mediterranean societies, remain hotly debated. Here, we unravel the history of wild olives (oleasters),…

Continue ReadingThe complex history of the olive tree: from Late Quaternary diversification of Mediterranean lineages to primary domestication in the northern Levant.