Read more about the article Turkish Cypriot paternal lineages bear an autochthonous character and closest resemblance to those from neighbouring Near Eastern populations.
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Turkish Cypriot paternal lineages bear an autochthonous character and closest resemblance to those from neighbouring Near Eastern populations.

Abstract Cyprus is an island in the Eastern Mediterranean Sea with a documented history of human settlements dating back over 10,000 years. To investigate the paternal lineages of a representative…

Continue ReadingTurkish Cypriot paternal lineages bear an autochthonous character and closest resemblance to those from neighbouring Near Eastern populations.
Read more about the article Pharmacological preconditioning for short-term ex vivo expansion of human umbilical cord blood hematopoietic stem cells by filgrastim.
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Pharmacological preconditioning for short-term ex vivo expansion of human umbilical cord blood hematopoietic stem cells by filgrastim.

Abstract Although umbilical cord blood (UCB) hematopoietic stem cell transplantation (UCBT) has emerged as a promising haematological reconstitution therapy for leukemias and other related disorders, the insufficient UCB stem cell…

Continue ReadingPharmacological preconditioning for short-term ex vivo expansion of human umbilical cord blood hematopoietic stem cells by filgrastim.
Read more about the article Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.
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Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.

Abstract Methylenetetrahydrofolate dehydrogenase (NAD(P)+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) is a mitochondrial enzyme involved in folate metabolism. A number of recent studies have highlighted this enzyme as being highly expressed…

Continue ReadingSuppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.
Read more about the article Investigating the Effect of Hydroalcoholic Extract of Cyperus rotundus L. on the Expression of Bcl-x1 Antiapoptotic Gene in Rats’ Hippocampus Tissue Following Global Ischemic-Reperfusion Injury.
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Investigating the Effect of Hydroalcoholic Extract of Cyperus rotundus L. on the Expression of Bcl-x1 Antiapoptotic Gene in Rats’ Hippocampus Tissue Following Global Ischemic-Reperfusion Injury.

Abstract Ischemia-reperfusion injury is the tissue damage happened when blood supply returns to the tissue after a period of ischemia or shortage of oxygen. This brain injury initiates an inflammatory…

Continue ReadingInvestigating the Effect of Hydroalcoholic Extract of Cyperus rotundus L. on the Expression of Bcl-x1 Antiapoptotic Gene in Rats’ Hippocampus Tissue Following Global Ischemic-Reperfusion Injury.
Read more about the article Analysis of dysregulated long non-coding RNA expressions in glioblastoma cells.
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Analysis of dysregulated long non-coding RNA expressions in glioblastoma cells.

Abstract Long non coding RNAs (lncRNAs) are associated with various biological roles such as embryogenesis, stem cell biology, cellular development and present specific tissue expression profiles. Aberrant expression of lncRNAs…

Continue ReadingAnalysis of dysregulated long non-coding RNA expressions in glioblastoma cells.
Read more about the article Differential expression of parental alleles of BRCA1 in human preimplantation embryos.
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Differential expression of parental alleles of BRCA1 in human preimplantation embryos.

Abstract Gene expression from both parental genomes is required for completion of embryogenesis. Differential methylation of each parental genome has been observed in mouse and human preimplantation embryos. It is…

Continue ReadingDifferential expression of parental alleles of BRCA1 in human preimplantation embryos.
Read more about the article Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd.
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Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd.

Abstract Gene expression data are accumulating exponentially in public repositories. Reanalysis and integration of themed collections from these studies may provide new insights, but requires further human curation. Here we…

Continue ReadingExtraction and analysis of signatures from the Gene Expression Omnibus by the crowd.
Read more about the article Associations between social vulnerabilities and dietary patterns in European children: the Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS) study.
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Associations between social vulnerabilities and dietary patterns in European children: the Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS) study.

Abstract Socio-economic inequalities in childhood can determine dietary patterns, and therefore future health. This study aimed to explore associations between social vulnerabilities and dietary patterns assessed at two time points,…

Continue ReadingAssociations between social vulnerabilities and dietary patterns in European children: the Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS) study.
Read more about the article Deletion of SNURF/SNRPN U1B and U1B* upstream exons in a child with developmental delay and excessive weight.
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Deletion of SNURF/SNRPN U1B and U1B* upstream exons in a child with developmental delay and excessive weight.

Abstract Prader-Willi syndrome is a rare syndrome characterized by hypotonia, developmental delay and excessive appetite. This syndrome is caused by the loss of function of paternally-expressed genes located in an…

Continue ReadingDeletion of SNURF/SNRPN U1B and U1B* upstream exons in a child with developmental delay and excessive weight.
Read more about the article Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.
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Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

Abstract Genome-wide association studies (GWASs) have revealed increased breast cancer risk associated with multiple genetic variants at 5p12. Here, we report the fine mapping of this locus using data from…

Continue ReadingEvidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.