Read more about the article A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics.
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A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics.

Abstract Pharmacogenomics aims to correlate inter-individual differences of drug efficacy and/or toxicity with the underlying genetic composition, particularly in genes encoding for protein factors and enzymes involved in drug metabolism…

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Read more about the article Clinical radiological correlation in E200K familial Creutzfeldt-Jakob disease.
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Clinical radiological correlation in E200K familial Creutzfeldt-Jakob disease.

Abstract The use of diffusion MRI improved the accuracy of diagnosis in Creutzfeldt-Jakob disease (CJD) and expanded our knowledge of the changes occurring in the brain during the disease. The…

Continue ReadingClinical radiological correlation in E200K familial Creutzfeldt-Jakob disease.
Read more about the article Detection of a Yersinia pestis gene homologue in rodent samples.
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Detection of a Yersinia pestis gene homologue in rodent samples.

Abstract A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and…

Continue ReadingDetection of a Yersinia pestis gene homologue in rodent samples.
Read more about the article Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).
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Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).

Abstract Genome-wide association studies have found SNPs at 17q22 to be associated with breast cancer risk. To identify potential causal variants related to breast cancer risk, we performed a high…

Continue ReadingFine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).
Read more about the article Longitudinal associations of lifestyle factors and weight status with insulin resistance (HOMA-IR) in preadolescent children: the large prospective cohort study IDEFICS.
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Longitudinal associations of lifestyle factors and weight status with insulin resistance (HOMA-IR) in preadolescent children: the large prospective cohort study IDEFICS.

Abstract This study investigates prospective associations of anthropometrical and lifestyle indices with insulin resistance (IR) in European children from the IDEFICS cohort. Insulin resistance (IR) is a growing concern in…

Continue ReadingLongitudinal associations of lifestyle factors and weight status with insulin resistance (HOMA-IR) in preadolescent children: the large prospective cohort study IDEFICS.
Read more about the article Phylogeography of the Koala, (Phascolarctos cinereus), and Harmonising Data to Inform Conservation.
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Phylogeography of the Koala, (Phascolarctos cinereus), and Harmonising Data to Inform Conservation.

Abstract The Australian continent exhibits complex biogeographic patterns but studies of the impacts of Pleistocene climatic oscillation on the mesic environments of the Southern Hemisphere are limited. The koala (Phascolarctos…

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Read more about the article Systemic inflammation disrupts oligodendrocyte gap junctions and induces ER stress in a model of CNS manifestations of X-linked Charcot-Marie-Tooth disease.
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Systemic inflammation disrupts oligodendrocyte gap junctions and induces ER stress in a model of CNS manifestations of X-linked Charcot-Marie-Tooth disease.

Abstract X-linked Charcot-Marie-Tooth disease (CMT1X) is a common form of inherited neuropathy resulting from different mutations affecting the gap junction (GJ) protein connexin32 (Cx32). A subset of CMT1X patients may…

Continue ReadingSystemic inflammation disrupts oligodendrocyte gap junctions and induces ER stress in a model of CNS manifestations of X-linked Charcot-Marie-Tooth disease.
Read more about the article Is "dried stool spots on filter paper method (DSSFP)" more sensitive and effective for detecting Blastocystis spp. and their subtypes by PCR and sequencing?
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Is "dried stool spots on filter paper method (DSSFP)" more sensitive and effective for detecting Blastocystis spp. and their subtypes by PCR and sequencing?

Abstract PCR and DNA sequencing are currently the diagnostic methods of choice for detection of Blastocystis spp. and their suptypes. Fresh or frozen stool samples have disadvantages in terms of…

Continue ReadingIs "dried stool spots on filter paper method (DSSFP)" more sensitive and effective for detecting Blastocystis spp. and their subtypes by PCR and sequencing?
Read more about the article Prevalence of Mediterranean FeVer Gene Mutations in Turkish Cypriot Population.
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Prevalence of Mediterranean FeVer Gene Mutations in Turkish Cypriot Population.

Abstract This study aims to determine the carrier frequency and the most common mutations of the Mediterranean FeVer (MEFV) gene in healthy Cypriot population of Turkish origin. A total of…

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Read more about the article iLIR database: A web resource for LIR motif-containing proteins in eukaryotes.
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iLIR database: A web resource for LIR motif-containing proteins in eukaryotes.

Abstract Atg8-family proteins are the best-studied proteins of the core autophagic machinery. They are essential for the elongation and closure of the phagophore into a proper autophagosome. Moreover, Atg8-family proteins…

Continue ReadingiLIR database: A web resource for LIR motif-containing proteins in eukaryotes.