Read more about the article Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.
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Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.

Abstract Methylenetetrahydrofolate dehydrogenase (NAD(P)+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) is a mitochondrial enzyme involved in folate metabolism. A number of recent studies have highlighted this enzyme as being highly expressed…

Continue ReadingSuppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.
Read more about the article Investigating the Effect of Hydroalcoholic Extract of Cyperus rotundus L. on the Expression of Bcl-x1 Antiapoptotic Gene in Rats’ Hippocampus Tissue Following Global Ischemic-Reperfusion Injury.
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Investigating the Effect of Hydroalcoholic Extract of Cyperus rotundus L. on the Expression of Bcl-x1 Antiapoptotic Gene in Rats’ Hippocampus Tissue Following Global Ischemic-Reperfusion Injury.

Abstract Ischemia-reperfusion injury is the tissue damage happened when blood supply returns to the tissue after a period of ischemia or shortage of oxygen. This brain injury initiates an inflammatory…

Continue ReadingInvestigating the Effect of Hydroalcoholic Extract of Cyperus rotundus L. on the Expression of Bcl-x1 Antiapoptotic Gene in Rats’ Hippocampus Tissue Following Global Ischemic-Reperfusion Injury.
Read more about the article Analysis of dysregulated long non-coding RNA expressions in glioblastoma cells.
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Analysis of dysregulated long non-coding RNA expressions in glioblastoma cells.

Abstract Long non coding RNAs (lncRNAs) are associated with various biological roles such as embryogenesis, stem cell biology, cellular development and present specific tissue expression profiles. Aberrant expression of lncRNAs…

Continue ReadingAnalysis of dysregulated long non-coding RNA expressions in glioblastoma cells.
Read more about the article Is "dried stool spots on filter paper method (DSSFP)" more sensitive and effective for detecting Blastocystis spp. and their subtypes by PCR and sequencing?
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Is "dried stool spots on filter paper method (DSSFP)" more sensitive and effective for detecting Blastocystis spp. and their subtypes by PCR and sequencing?

Abstract PCR and DNA sequencing are currently the diagnostic methods of choice for detection of Blastocystis spp. and their suptypes. Fresh or frozen stool samples have disadvantages in terms of…

Continue ReadingIs "dried stool spots on filter paper method (DSSFP)" more sensitive and effective for detecting Blastocystis spp. and their subtypes by PCR and sequencing?
Read more about the article Prevalence of Mediterranean FeVer Gene Mutations in Turkish Cypriot Population.
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Prevalence of Mediterranean FeVer Gene Mutations in Turkish Cypriot Population.

Abstract This study aims to determine the carrier frequency and the most common mutations of the Mediterranean FeVer (MEFV) gene in healthy Cypriot population of Turkish origin. A total of…

Continue ReadingPrevalence of Mediterranean FeVer Gene Mutations in Turkish Cypriot Population.
Read more about the article iLIR database: A web resource for LIR motif-containing proteins in eukaryotes.
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iLIR database: A web resource for LIR motif-containing proteins in eukaryotes.

Abstract Atg8-family proteins are the best-studied proteins of the core autophagic machinery. They are essential for the elongation and closure of the phagophore into a proper autophagosome. Moreover, Atg8-family proteins…

Continue ReadingiLIR database: A web resource for LIR motif-containing proteins in eukaryotes.
Read more about the article The Impacts of miRNAs in Glioblastoma Progression.
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The Impacts of miRNAs in Glioblastoma Progression.

Abstract miRNAs are short noncoding RNA sequences that cause translational repression or mRNA degradation. A growing number of studies have sought new biomarkers in GBM that will be important in…

Continue ReadingThe Impacts of miRNAs in Glioblastoma Progression.
Read more about the article Ethical Dilemmas for Oocyte Donations: Slippery Slope for Conflicts of Interest.
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Ethical Dilemmas for Oocyte Donations: Slippery Slope for Conflicts of Interest.

Abstract Oocyte donations have increased with improvements in oocyte cryopreservation procedures in recent years. Women with medical conditions that require chemotherapy or radiotherapy have begun to opt for oocyte cryo¬preservation…

Continue ReadingEthical Dilemmas for Oocyte Donations: Slippery Slope for Conflicts of Interest.
Read more about the article Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes.
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Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes.

Abstract The insufficient ability of specialized cells such as neurons, cardiac myocytes, and epidermal cells to regenerate after tissue damage poses a great challenge to treat devastating injuries and ailments.…

Continue ReadingDirect conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes.
Read more about the article Beta thalassaemia intermedia due to co-inheritance of three unique alpha globin cluster duplications characterised by next generation sequencing analysis.
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Beta thalassaemia intermedia due to co-inheritance of three unique alpha globin cluster duplications characterised by next generation sequencing analysis.

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Abstract

Continue ReadingBeta thalassaemia intermedia due to co-inheritance of three unique alpha globin cluster duplications characterised by next generation sequencing analysis.