Read more about the article miR-378 inhibits cell growth and enhances apoptosis in human myelodysplastic syndromes.
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miR-378 inhibits cell growth and enhances apoptosis in human myelodysplastic syndromes.

Abstract miR-378 has been proven to inhibit cell growth, migration and invasion in different types of cancers. In this study, we found that miR-378 was commonly downregulated in the bone…

Continue ReadingmiR-378 inhibits cell growth and enhances apoptosis in human myelodysplastic syndromes.
Read more about the article Assessing the potential of pharmaceuticals and their transformation products to cause mutagenic effects: Implications for gene expression profiling.
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Assessing the potential of pharmaceuticals and their transformation products to cause mutagenic effects: Implications for gene expression profiling.

Abstract The selection and prioritization of pharmaceuticals and their transformation products for evaluating effects on the environment and human health is a challenging task. One common approach is based on…

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Read more about the article Kisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells.
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Kisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells.

Abstract Uterine tissue was collected from bitches after ovariohysterectomy at different times after ovulation. Samples were assigned to four groups: metestrous non-pregnant, day 10-12, n = 4; pre-implantation, day 10-12, n = 9; post-implantation,…

Continue ReadingKisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells.
Read more about the article Associations between exclusive breastfeeding and physical fitness during childhood.
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Associations between exclusive breastfeeding and physical fitness during childhood.

Abstract Exposure to breastfeeding improves the survival, health, and development of children; therefore, breast milk is recommended as the exclusive nutrient source for feeding term infants during the first 6 months.…

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Read more about the article A synthesis of radial growth patterns preceding tree mortality.
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A synthesis of radial growth patterns preceding tree mortality.

Abstract Tree mortality is a key factor influencing forest functions and dynamics, but our understanding of the mechanisms leading to mortality and the associated changes in tree growth rates are…

Continue ReadingA synthesis of radial growth patterns preceding tree mortality.
Read more about the article Association of desaturase activity and C-reactive protein in European children.
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Association of desaturase activity and C-reactive protein in European children.

Abstract Desaturase enzymes influence the fatty acid (FA) composition of body tissues and their activity affects the conversion rate of saturated to monounsaturated FA and of polyunsaturated FA (PUFA) to…

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Read more about the article Unsupervised data-driven stratification of mentalizing heterogeneity in autism.
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Unsupervised data-driven stratification of mentalizing heterogeneity in autism.

Abstract Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous. Novel approaches are needed to parse this heterogeneity to enhance precision in clinical and translational research. Applying a clustering…

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Read more about the article Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
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Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.

Abstract The results of the study reported here are part of an ongoing integrated research programme aimed at producing additional, robust, evidence on the genetic resistance to classical scrapie in…

Continue ReadingGoats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
Read more about the article Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.
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Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.

Abstract P.I157T is a CHEK2 missense mutation associated with a modest increase in breast cancer risk. Previously, another CHEK2 mutation, the protein truncating c.1100delC has been associated with poor prognosis…

Continue ReadingPatient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.
Read more about the article Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.
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Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

Abstract CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk…

Continue ReadingGenetic modifiers of CHEK2*1100delC-associated breast cancer risk.