Read more about the article MicroRNAs and Aging: Biomarkers or Therapeutic Targets?
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MicroRNAs and Aging: Biomarkers or Therapeutic Targets?

Abstract Understanding the molecular mechanism of aging is of utmost importance to the scientific communities. To date, various theories have been proposed and many of them were evaluated as potential…

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Read more about the article BRCA1 and BRCA2 mutation testing in Cyprus; a population based study.
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BRCA1 and BRCA2 mutation testing in Cyprus; a population based study.

Abstract This paper presents the largest study in Cyprus evaluating the frequency and distribution of BRCA1/2 mutations in a high risk patient cohort. Deleterious mutations in the BRCA1/2 genes were…

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Read more about the article Biomarkers of systemic lupus erythematosus identified using mass spectrometry-based proteomics: a systematic review.
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Biomarkers of systemic lupus erythematosus identified using mass spectrometry-based proteomics: a systematic review.

Abstract Advances in mass spectrometry technologies have created new opportunities for discovering novel protein biomarkers in systemic lupus erythematosus (SLE). We performed a systematic review of published reports on proteomic…

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Read more about the article Mediterranean diet-gene interactions: A targeted metabolomics study in Greek-Cypriot women.
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Mediterranean diet-gene interactions: A targeted metabolomics study in Greek-Cypriot women.

Abstract A high adherence to the Mediterranean diet (MD) was previously associated with a decreased risk of breast cancer (BC) among Greek-Cypriot women. Additionally, particular polymorphisms were shown to modulate…

Continue ReadingMediterranean diet-gene interactions: A targeted metabolomics study in Greek-Cypriot women.
Read more about the article rs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk.
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rs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk.

Abstract NBS1, also known as NBN, plays an important role in maintaining genomic stability. Interestingly, rs2735383 G > C, located in a microRNA binding site in the 3'-untranslated region (UTR) of NBS1,…

Continue Readingrs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk.
Read more about the article Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions.
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Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions.

Abstract DNA methylation is an epigenetic marker that has been shown to vary significantly across different tissues. Taking advantage of the methylation differences between placenta-derived cell-free DNA and maternal blood,…

Continue ReadingWhole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions.
Read more about the article Plasma pentraxin-3 is associated with endothelial dysfunction in non-alcoholic fatty liver disease.
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Plasma pentraxin-3 is associated with endothelial dysfunction in non-alcoholic fatty liver disease.

Abstract Pentraxin-3 (PTX-3) is an acute-phase protein belonging to the PTX family. It has been reported that PTX-3 is significantly associated with obesity, metabolic syndrome, and cardiovascular diseases (CVD). Non-alcoholic…

Continue ReadingPlasma pentraxin-3 is associated with endothelial dysfunction in non-alcoholic fatty liver disease.
Read more about the article Glucosinolate biosynthesis in Eruca sativa.
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Glucosinolate biosynthesis in Eruca sativa.

Abstract Glucosinolates (GSLs) are a highly important group of secondary metabolites in the Caparalles order, both due to their significance in plant-biome interactions and to their chemoprotective properties. This study…

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Read more about the article A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study.
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A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study.

Abstract The melanocortin-4 receptor gene (MC4R) plays a pivotal role in the regulation of body fat and food and energy intake. The objectives of the study were as follows: 1)…

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Read more about the article Diagnosis and management of Silver-Russell syndrome: first international consensus statement.
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Diagnosis and management of Silver-Russell syndrome: first international consensus statement.

Abstract This Consensus Statement summarizes recommendations for clinical diagnosis, investigation and management of patients with Silver-Russell syndrome (SRS), an imprinting disorder that causes prenatal and postnatal growth retardation. Considerable overlap…

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