Read more about the article Incidence of end-stage renal disease in the Turkish-Cypriot population of Northern Cyprus: a population based study.
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Incidence of end-stage renal disease in the Turkish-Cypriot population of Northern Cyprus: a population based study.

Abstract This is the first report of the incidence and causes of end-stage renal disease (ESRD) of the Turkish-Cypriot population in Northern Cyprus. Data were collected over eight consecutive years…

Continue ReadingIncidence of end-stage renal disease in the Turkish-Cypriot population of Northern Cyprus: a population based study.
Read more about the article Relative validity of the Children’s Eating Habits Questionnaire-food frequency section among young European children: the IDEFICS Study.
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Relative validity of the Children’s Eating Habits Questionnaire-food frequency section among young European children: the IDEFICS Study.

Abstract To compare, specifically by age group, proxy-reported food group estimates obtained from the food frequency section of the Children's Eating Habits questionnaire (CEHQ-FFQ) against the estimates of two non-consecutive…

Continue ReadingRelative validity of the Children’s Eating Habits Questionnaire-food frequency section among young European children: the IDEFICS Study.
Read more about the article BRCA1 and Its Network of Interacting Partners.
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BRCA1 and Its Network of Interacting Partners.

Abstract BRCA1 is a large multi-domain protein with a pivotal role in maintaining genome stability and cell cycle progression. Germline mutations in the BRCA1 gene confer an estimated lifetime risk…

Continue ReadingBRCA1 and Its Network of Interacting Partners.
Read more about the article The spectrum of α-thalassemia mutations in the Kurdish population of Northeastern Iraq.
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The spectrum of α-thalassemia mutations in the Kurdish population of Northeastern Iraq.

Abstract In an attempt to determine the spectrum of α-thalassemia (α-thal) mutations in the Kurdish population of Northeastern (NE) Iraq, a total of 101 unrelated adults with unexplained hypochromia and/or…

Continue ReadingThe spectrum of α-thalassemia mutations in the Kurdish population of Northeastern Iraq.
Read more about the article Pig domestication and human-mediated dispersal in western Eurasia revealed through ancient DNA and geometric morphometrics.
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Pig domestication and human-mediated dispersal in western Eurasia revealed through ancient DNA and geometric morphometrics.

Abstract Zooarcheological evidence suggests that pigs were domesticated in Southwest Asia ~8,500 BC. They then spread across the Middle and Near East and westward into Europe alongside early agriculturalists. European…

Continue ReadingPig domestication and human-mediated dispersal in western Eurasia revealed through ancient DNA and geometric morphometrics.
Read more about the article Prevalence of thrombosis-related DNA polymorphisms in a healthy Greek population.
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Prevalence of thrombosis-related DNA polymorphisms in a healthy Greek population.

Abstract Genetic association studies have revealed a correlation between DNA variations in genes encoding factors of the haemostatic system and thrombosis-related disease. This study investigated the prevalence of 13 such…

Continue ReadingPrevalence of thrombosis-related DNA polymorphisms in a healthy Greek population.
Read more about the article A novel oral nutraceutical formula of omega-3 and omega-6 fatty acids with vitamins (PLP10) in relapsing remitting multiple sclerosis: a randomised, double-blind, placebo-controlled proof-of-concept clinical trial.
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A novel oral nutraceutical formula of omega-3 and omega-6 fatty acids with vitamins (PLP10) in relapsing remitting multiple sclerosis: a randomised, double-blind, placebo-controlled proof-of-concept clinical trial.

Abstract To assess whether three novel interventions, formulated based on a systems medicine therapeutic concept, reduced disease activity in patients with relapsing-remitting multiple sclerosis (MS) who were either treated or…

Continue ReadingA novel oral nutraceutical formula of omega-3 and omega-6 fatty acids with vitamins (PLP10) in relapsing remitting multiple sclerosis: a randomised, double-blind, placebo-controlled proof-of-concept clinical trial.
Read more about the article Next generation sequencing of SNPs for non-invasive prenatal diagnosis: challenges and feasibility as illustrated by an application to β-thalassaemia.
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Next generation sequencing of SNPs for non-invasive prenatal diagnosis: challenges and feasibility as illustrated by an application to β-thalassaemia.

Abstract β-Thalassaemia is one of the most common autosomal recessive single-gene disorder worldwide, with a carrier frequency of 12% in Cyprus. Prenatal tests for at risk pregnancies use invasive methods…

Continue ReadingNext generation sequencing of SNPs for non-invasive prenatal diagnosis: challenges and feasibility as illustrated by an application to β-thalassaemia.
Read more about the article Implementation of high resolution whole genome array CGH in the prenatal clinical setting: advantages, challenges, and review of the literature.
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Implementation of high resolution whole genome array CGH in the prenatal clinical setting: advantages, challenges, and review of the literature.

Abstract Array Comparative Genomic Hybridization analysis is replacing postnatal chromosomal analysis in cases of intellectual disabilities, and it has been postulated that it might also become the first-tier test in…

Continue ReadingImplementation of high resolution whole genome array CGH in the prenatal clinical setting: advantages, challenges, and review of the literature.
Read more about the article Epistatic role of the MYH9/APOL1 region on familial hematuria genes.
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Epistatic role of the MYH9/APOL1 region on familial hematuria genes.

Abstract Familial hematuria (FH) is explained by at least four different genes (see below). About 50% of patients develop late proteinuria and chronic kidney disease (CKD). We hypothesized that MYH9/APOL1,…

Continue ReadingEpistatic role of the MYH9/APOL1 region on familial hematuria genes.