Read more about the article Characterization of the Sandfly fever Naples species complex and description of a new Karimabad species complex (genus Phlebovirus, family Bunyaviridae).
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Characterization of the Sandfly fever Naples species complex and description of a new Karimabad species complex (genus Phlebovirus, family Bunyaviridae).

Abstract Genomic and antigenic characterization of members of the Sandfly fever Naples virus (SFNV) complex reveals the presence of five clades that differ in their geographical distribution. Saint Floris and…

Continue ReadingCharacterization of the Sandfly fever Naples species complex and description of a new Karimabad species complex (genus Phlebovirus, family Bunyaviridae).
Read more about the article Calpain2 protease: A new member of the Wnt/Ca(2+) pathway modulating convergent extension movements in Xenopus.
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Calpain2 protease: A new member of the Wnt/Ca(2+) pathway modulating convergent extension movements in Xenopus.

Abstract Calpains are a family of calcium-dependent intracellular cysteine proteases that regulate several physiological processes by limited cleavage of different substrates. The role of Calpain2 in embryogenesis is not clear…

Continue ReadingCalpain2 protease: A new member of the Wnt/Ca(2+) pathway modulating convergent extension movements in Xenopus.
Read more about the article Autism.
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Autism.

Abstract Autism is a set of heterogeneous neurodevelopmental conditions, characterised by early-onset difficulties in social communication and unusually restricted, repetitive behaviour and interests. The worldwide population prevalence is about 1%.…

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Read more about the article N-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing.
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N-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing.

Abstract Post-translational modifications of histones play a key role in DNA-based processes, like transcription, by modulating chromatin structure. N-terminal acetylation is unique among the numerous histone modifications because it is…

Continue ReadingN-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing.
Read more about the article Irisin mRNA and circulating levels in relation to other myokines in healthy and morbidly obese humans.
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Irisin mRNA and circulating levels in relation to other myokines in healthy and morbidly obese humans.

Abstract Skeletal muscle is considered to be an endocrine organ that secretes a number of myokines including follistatin (FST), myostatin (MSTN), activin A, and the newly identified irisin. Irisin's biology…

Continue ReadingIrisin mRNA and circulating levels in relation to other myokines in healthy and morbidly obese humans.
Read more about the article Family structure and childhood obesity: results of the IDEFICS Project.
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Family structure and childhood obesity: results of the IDEFICS Project.

Abstract To analyse the association between family structure and adiposity in children. Cross-sectional and longitudinal analysis of the IDEFICS (Identification and prevention of dietary- and lifestyle-induced health effects in children…

Continue ReadingFamily structure and childhood obesity: results of the IDEFICS Project.
Read more about the article A dominant-negative provides new insights into FAK regulation and function in early embryonic morphogenesis.
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A dominant-negative provides new insights into FAK regulation and function in early embryonic morphogenesis.

Abstract FAK is a non-receptor tyrosine kinase involved in a wide variety of biological processes and crucial for embryonic development. In this manuscript, we report the generation of a new…

Continue ReadingA dominant-negative provides new insights into FAK regulation and function in early embryonic morphogenesis.
Read more about the article Molecular genetics of familial hematuric diseases.
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Molecular genetics of familial hematuric diseases.

Abstract The familial hematuric diseases are a genetically heterogeneous group of monogenic conditions, caused by mutations in one of several genes. The major genes involved are the following: (i) the…

Continue ReadingMolecular genetics of familial hematuric diseases.
Read more about the article Association of genotypes at the matrix metalloproteinase (MMP) loci with carotid IMT and presence of carotid and femoral atherosclerotic plaques.
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Association of genotypes at the matrix metalloproteinase (MMP) loci with carotid IMT and presence of carotid and femoral atherosclerotic plaques.

Abstract We aimed to test the association between matrix metalloproteinase (MMP) genetic polymorphisms and (a) intima-media thickness in the common carotid (IMTcc) and (b) the presence of plaques in the…

Continue ReadingAssociation of genotypes at the matrix metalloproteinase (MMP) loci with carotid IMT and presence of carotid and femoral atherosclerotic plaques.
Read more about the article A novel GBA2 gene missense mutation in spastic ataxia.
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A novel GBA2 gene missense mutation in spastic ataxia.

Abstract Autosomal recessive cerebellar ataxias (ARCA) encompass a heterogeneous group of rare diseases that affect the cerebellum, the spinocerebellar tract and/or the sensory tracts of the spinal cord. We investigated…

Continue ReadingA novel GBA2 gene missense mutation in spastic ataxia.