Read more about the article Epistatic role of the MYH9/APOL1 region on familial hematuria genes.
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Epistatic role of the MYH9/APOL1 region on familial hematuria genes.

Abstract Familial hematuria (FH) is explained by at least four different genes (see below). About 50% of patients develop late proteinuria and chronic kidney disease (CKD). We hypothesized that MYH9/APOL1,…

Continue ReadingEpistatic role of the MYH9/APOL1 region on familial hematuria genes.
Read more about the article Mediterranean diet, overweight and body composition in children from eight European countries: cross-sectional and prospective results from the IDEFICS study.
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Mediterranean diet, overweight and body composition in children from eight European countries: cross-sectional and prospective results from the IDEFICS study.

Abstract A Mediterranean-like dietary pattern has been shown to be inversely associated with many diseases, but its role in early obesity prevention is not clear. We aimed to determine if…

Continue ReadingMediterranean diet, overweight and body composition in children from eight European countries: cross-sectional and prospective results from the IDEFICS study.
Read more about the article Developmental stage- and concentration-specific sodium nitroprusside application results in nitrate reductase regulation and the modification of nitrate metabolism in leaves of Medicago truncatula plants.
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Developmental stage- and concentration-specific sodium nitroprusside application results in nitrate reductase regulation and the modification of nitrate metabolism in leaves of Medicago truncatula plants.

Abstract Nitric oxide (NO) is a bioactive molecule involved in numerous biological events that has been reported to display both pro-oxidant and antioxidant properties in plants. Several reports exist which…

Continue ReadingDevelopmental stage- and concentration-specific sodium nitroprusside application results in nitrate reductase regulation and the modification of nitrate metabolism in leaves of Medicago truncatula plants.
Read more about the article Pax6 is expressed in subsets of V0 and V2 interneurons in the ventral spinal cord in mice.
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Pax6 is expressed in subsets of V0 and V2 interneurons in the ventral spinal cord in mice.

Abstract The embryonic spinal cord in mice is organized into eleven progenitor domains. Cells in each domain first produce neurons and then switch to specifying glia. Five of these domains…

Continue ReadingPax6 is expressed in subsets of V0 and V2 interneurons in the ventral spinal cord in mice.
Read more about the article Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance.
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Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance.

Abstract The purpose of this work is to determine the molecular mechanisms underlying tamoxifen resistance. We show here that ER-β is epigenetically silenced in a cell line with acquired tamoxifen…

Continue ReadingReversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance.
Read more about the article Intraperitoneal melatonin is not neuroprotective in the G93ASOD1 transgenic mouse model of familial ALS and may exacerbate neurodegeneration.
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Intraperitoneal melatonin is not neuroprotective in the G93ASOD1 transgenic mouse model of familial ALS and may exacerbate neurodegeneration.

Abstract In amyotrophic lateral sclerosis (ALS) reactive oxygen species and apoptosis are implicated in disease pathogenesis. Melatonin with its anti-oxidant and anti-apoptotic properties is expected to ameliorate disease phenotype. The…

Continue ReadingIntraperitoneal melatonin is not neuroprotective in the G93ASOD1 transgenic mouse model of familial ALS and may exacerbate neurodegeneration.
Read more about the article Cross-talk among epigenetic modifications: lessons from histone arginine methylation.
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Cross-talk among epigenetic modifications: lessons from histone arginine methylation.

Abstract Epigenetic modifications, including those occurring on DNA and on histone proteins, control gene expression by establishing and maintaining different chromatin states. In recent years, it has become apparent that…

Continue ReadingCross-talk among epigenetic modifications: lessons from histone arginine methylation.
Read more about the article The HPV16 oncogenes cause aberrant stem cell mobilization.
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The HPV16 oncogenes cause aberrant stem cell mobilization.

Abstract Human Papilloma Virus related epithelial cancers have been speculated to derive from virus-infected tissue stem cells. Stem cells also are thought to provide a reservoir of latently infected cells…

Continue ReadingThe HPV16 oncogenes cause aberrant stem cell mobilization.
Read more about the article Turkish perspective of Jervell and Lange-Nielsen syndrome.
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Turkish perspective of Jervell and Lange-Nielsen syndrome.

Abstract

Continue ReadingTurkish perspective of Jervell and Lange-Nielsen syndrome.
Read more about the article EFNS review on the role of muscle biopsy in the investigation of myalgia.
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EFNS review on the role of muscle biopsy in the investigation of myalgia.

Abstract Myalgia, defined as any pain perceived in muscle, is very common in the general population and a frequent cause for referral to neurologists, rheumatologists and internists in general. It…

Continue ReadingEFNS review on the role of muscle biopsy in the investigation of myalgia.