Read more about the article Lessons learned–resolving the enigma of genetic factors in IBS.
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Lessons learned–resolving the enigma of genetic factors in IBS.

Abstract IBS is the most prevalent functional gastrointestinal disorder and phenotypically characterized by chronic abdominal discomfort, pain and altered defecation patterns. The pathophysiology of IBS is multifactorial, albeit with a…

Continue ReadingLessons learned–resolving the enigma of genetic factors in IBS.
Read more about the article Adherence to combined lifestyle factors and their contribution to obesity in the IDEFICS study.
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Adherence to combined lifestyle factors and their contribution to obesity in the IDEFICS study.

Abstract The Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS) study investigated the aetiology of childhood obesity and developed a primary prevention programme. Pre-intervention…

Continue ReadingAdherence to combined lifestyle factors and their contribution to obesity in the IDEFICS study.
Read more about the article Fat, sugar and water intakes among families from the IDEFICS intervention and control groups: first observations from I.Family.
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Fat, sugar and water intakes among families from the IDEFICS intervention and control groups: first observations from I.Family.

Abstract The objective of this paper is to investigate differences in diets of families in intervention versus control communities 5 years after the Identification and Prevention of Dietary- and Lifestyle-Induced Health…

Continue ReadingFat, sugar and water intakes among families from the IDEFICS intervention and control groups: first observations from I.Family.
Read more about the article Differential outcome of the IDEFICS intervention in overweight versus non-overweight children: did we achieve ‘primary’ or ‘secondary’ prevention?
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Differential outcome of the IDEFICS intervention in overweight versus non-overweight children: did we achieve ‘primary’ or ‘secondary’ prevention?

Abstract The aim of this study was to explore whether the IDEFICS intervention had a differential effect on 11,041 children's weight trajectories depending on their baseline body mass index status.…

Continue ReadingDifferential outcome of the IDEFICS intervention in overweight versus non-overweight children: did we achieve ‘primary’ or ‘secondary’ prevention?
Read more about the article A novel variant in male siblings with intellectual disability and microcephaly in the absence of cobalamin disorder.
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A novel variant in male siblings with intellectual disability and microcephaly in the absence of cobalamin disorder.

Abstract Approximately 10-15% of intellectual disability (ID) cases are caused by genetic aberrations affecting chromosome X, a condition termed X-linked ID (XLID). Examination by whole-exome sequencing of two male siblings…

Continue ReadingA novel variant in male siblings with intellectual disability and microcephaly in the absence of cobalamin disorder.
Read more about the article Physical and verbal aggressive behavior and COMT genotype: Sensitivity to the environment.
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Physical and verbal aggressive behavior and COMT genotype: Sensitivity to the environment.

Abstract Catechol-O-methyltransferase (COMT) genotype has been implicated as a vulnerability factor for several psychiatric diseases as well as aggressive behavior, either directly, or in interaction with an adverse environment. The…

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Read more about the article Prevalence of RhD status and clinical application of non-invasive prenatal determination of fetal RHD in maternal plasma: a 5 year experience in Cyprus.
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Prevalence of RhD status and clinical application of non-invasive prenatal determination of fetal RHD in maternal plasma: a 5 year experience in Cyprus.

Abstract After the discovery that cell-free fetal DNA (cffDNA) is circulating in the maternal plasma of pregnant women, non-invasive prenatal diagnosis for fetal RhD in maternal plasma in RhD negative…

Continue ReadingPrevalence of RhD status and clinical application of non-invasive prenatal determination of fetal RHD in maternal plasma: a 5 year experience in Cyprus.
Read more about the article Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy.
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Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy.

Abstract Inherited demyelinating peripheral neuropathies are progressive incurable diseases without effective treatment. To develop a gene therapy approach targeting myelinating Schwann cells that can be translatable, we delivered a lentiviral…

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Read more about the article Assessing the Relationship between Neurocognitive Performance and Brain Volume in Chronic Moderate-Severe Traumatic Brain Injury.
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Assessing the Relationship between Neurocognitive Performance and Brain Volume in Chronic Moderate-Severe Traumatic Brain Injury.

Abstract Characterize the scale and pattern of long-term atrophy in gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) in chronic moderate-severe traumatic brain injury (TBI) and its relationship…

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Read more about the article Geographical Distribution of MDR1 Expression in Leishmania Isolates, from Greece and Cyprus, Measured by the Rhodamine-123 Efflux Potential of the Isolates, Using Flow Cytometry.
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Geographical Distribution of MDR1 Expression in Leishmania Isolates, from Greece and Cyprus, Measured by the Rhodamine-123 Efflux Potential of the Isolates, Using Flow Cytometry.

Abstract Leishmaniasis, a neglected vector-borne disease caused by the protozoan parasite Leishmania, is encountered in 98 countries causing serious concerns to public health. The most alarming is the development of…

Continue ReadingGeographical Distribution of MDR1 Expression in Leishmania Isolates, from Greece and Cyprus, Measured by the Rhodamine-123 Efflux Potential of the Isolates, Using Flow Cytometry.