Read more about the article Transmembrane protein TMEM170A is a newly discovered regulator of ER and nuclear envelope morphogenesis in human cells.
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Transmembrane protein TMEM170A is a newly discovered regulator of ER and nuclear envelope morphogenesis in human cells.

Abstract The mechanism of endoplasmic reticulum (ER) morphogenesis is incompletely understood. ER tubules are shaped by the reticulons (RTNs) and DP1/Yop1p family members, but the mechanism of ER sheet formation…

Continue ReadingTransmembrane protein TMEM170A is a newly discovered regulator of ER and nuclear envelope morphogenesis in human cells.
Read more about the article Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status.
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Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status.

Abstract Hepatocellular carcinoma is the second deadliest cancer with limited treatment options. Loss of PTEN causes the P13K/Akt pathway to be hyperactive which contributes to cell survival and resistance to…

Continue ReadingLiver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status.
Read more about the article Early Life Factors and Inter-Country Heterogeneity in BMI Growth Trajectories of European Children: The IDEFICS Study.
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Early Life Factors and Inter-Country Heterogeneity in BMI Growth Trajectories of European Children: The IDEFICS Study.

Abstract Starting from birth, this explorative study aimed to investigate between-country differences in body mass index (BMI) trajectories and whether early life factors explain these differences. The sample included 7,644…

Continue ReadingEarly Life Factors and Inter-Country Heterogeneity in BMI Growth Trajectories of European Children: The IDEFICS Study.
Read more about the article The investigation of resveratrol and analogs as potential inducers of fetal hemoglobin.
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The investigation of resveratrol and analogs as potential inducers of fetal hemoglobin.

Abstract Βeta-thalassemia, is a hemoglobinopathy characterized by reduced beta-globin chain synthesis, leading to imbalanced globin chain production, ineffective erythropoiesis and anemia. Increasing gamma-globin gene expression is a promising therapeutic approach…

Continue ReadingThe investigation of resveratrol and analogs as potential inducers of fetal hemoglobin.
Read more about the article Pilot Experience with an External Quality Assurance Scheme for Acylcarnitines in Plasma/Serum.
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Pilot Experience with an External Quality Assurance Scheme for Acylcarnitines in Plasma/Serum.

Abstract The analysis of acylcarnitines (AC) in plasma/serum is established as a useful test for the biochemical diagnosis and the monitoring of treatment of organic acidurias and fatty acid oxidation…

Continue ReadingPilot Experience with an External Quality Assurance Scheme for Acylcarnitines in Plasma/Serum.
Read more about the article Nutri-epigenetics and synthetic analogs in cancer chemoprevention.
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Nutri-epigenetics and synthetic analogs in cancer chemoprevention.

Abstract Nutri-epigenetics has lately emerged as a new field in cancer epigenetic research. Cancer represents a multistage and heterogeneous disease that is driven by progressive genetic and epigenetic abnormalities. Epigenetic…

Continue ReadingNutri-epigenetics and synthetic analogs in cancer chemoprevention.
Read more about the article Determinant factors of physical fitness in European children.
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Determinant factors of physical fitness in European children.

Abstract This study was designed to explore the determinants of physical fitness in European children aged 6-11 years, cross-sectionally and longitudinally. There were sufficient data on 4903 children (50.6 % girls) on…

Continue ReadingDeterminant factors of physical fitness in European children.
Read more about the article Prevalence of RhD status and clinical application of non-invasive prenatal determination of fetal RHD in maternal plasma: a 5 year experience in Cyprus.
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Prevalence of RhD status and clinical application of non-invasive prenatal determination of fetal RHD in maternal plasma: a 5 year experience in Cyprus.

Abstract After the discovery that cell-free fetal DNA (cffDNA) is circulating in the maternal plasma of pregnant women, non-invasive prenatal diagnosis for fetal RhD in maternal plasma in RhD negative…

Continue ReadingPrevalence of RhD status and clinical application of non-invasive prenatal determination of fetal RHD in maternal plasma: a 5 year experience in Cyprus.
Read more about the article Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy.
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Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy.

Abstract Inherited demyelinating peripheral neuropathies are progressive incurable diseases without effective treatment. To develop a gene therapy approach targeting myelinating Schwann cells that can be translatable, we delivered a lentiviral…

Continue ReadingIntrathecal gene therapy rescues a model of demyelinating peripheral neuropathy.
Read more about the article Assessing the Relationship between Neurocognitive Performance and Brain Volume in Chronic Moderate-Severe Traumatic Brain Injury.
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Assessing the Relationship between Neurocognitive Performance and Brain Volume in Chronic Moderate-Severe Traumatic Brain Injury.

Abstract Characterize the scale and pattern of long-term atrophy in gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) in chronic moderate-severe traumatic brain injury (TBI) and its relationship…

Continue ReadingAssessing the Relationship between Neurocognitive Performance and Brain Volume in Chronic Moderate-Severe Traumatic Brain Injury.