Read more about the article Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status.
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Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status.

Abstract Hepatocellular carcinoma is the second deadliest cancer with limited treatment options. Loss of PTEN causes the P13K/Akt pathway to be hyperactive which contributes to cell survival and resistance to…

Continue ReadingLiver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status.
Read more about the article Early Life Factors and Inter-Country Heterogeneity in BMI Growth Trajectories of European Children: The IDEFICS Study.
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Early Life Factors and Inter-Country Heterogeneity in BMI Growth Trajectories of European Children: The IDEFICS Study.

Abstract Starting from birth, this explorative study aimed to investigate between-country differences in body mass index (BMI) trajectories and whether early life factors explain these differences. The sample included 7,644…

Continue ReadingEarly Life Factors and Inter-Country Heterogeneity in BMI Growth Trajectories of European Children: The IDEFICS Study.
Read more about the article Pilot Experience with an External Quality Assurance Scheme for Acylcarnitines in Plasma/Serum.
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Pilot Experience with an External Quality Assurance Scheme for Acylcarnitines in Plasma/Serum.

Abstract The analysis of acylcarnitines (AC) in plasma/serum is established as a useful test for the biochemical diagnosis and the monitoring of treatment of organic acidurias and fatty acid oxidation…

Continue ReadingPilot Experience with an External Quality Assurance Scheme for Acylcarnitines in Plasma/Serum.
Read more about the article Pester power and its consequences: do European children’s food purchasing requests relate to diet and weight outcomes?
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Pester power and its consequences: do European children’s food purchasing requests relate to diet and weight outcomes?

Abstract Children may influence household spending through 'pester power'. The present study examined pestering through parent-child food shopping behaviours in relation to children's diet and weight status. Cross-sectional and prospective…

Continue ReadingPester power and its consequences: do European children’s food purchasing requests relate to diet and weight outcomes?
Read more about the article The association between IgG and IgM antibodies against cardiolipin, β2-glycoprotein I and Domain I of β2-glycoprotein I with disease profile in patients with multiple sclerosis.
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The association between IgG and IgM antibodies against cardiolipin, β2-glycoprotein I and Domain I of β2-glycoprotein I with disease profile in patients with multiple sclerosis.

Abstract Antiphospholipid antibodies (aPL) occur in patients with multiple sclerosis (MS) with a number of studies reporting elevated levels; their exact prevalence and pathogenic role remain unclear. Epidemiological studies associate…

Continue ReadingThe association between IgG and IgM antibodies against cardiolipin, β2-glycoprotein I and Domain I of β2-glycoprotein I with disease profile in patients with multiple sclerosis.
Read more about the article Human Mesenchymal Stem Cells in Cancer Therapy.
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Human Mesenchymal Stem Cells in Cancer Therapy.

Abstract Human mesenchymal stem cells (hMSCs) have the ability to differentiate into several tissue types. Their use in cancer therapeutics or as therapeutic delivery vehicles has significant potential, particularly in…

Continue ReadingHuman Mesenchymal Stem Cells in Cancer Therapy.
Read more about the article The Importance of Mutational Drivers in GBM.
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The Importance of Mutational Drivers in GBM.

Abstract Glioblastoma (GBM) is the most aggressive primary brain tumor, providing few effective therapeutic options, given the tumor heterogeneity and the accumulation of different genetic abnormalities that cause treatment failure.…

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Read more about the article Clinical outcomes in children with herpes simplex encephalitis receiving steroid therapy.
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Clinical outcomes in children with herpes simplex encephalitis receiving steroid therapy.

Abstract Herpes simplex virus encephalitis (HSE) is a significant cause of morbidity and mortality. Neurologic sequelae are common even after early initiation of acyclovir treatment. The host immune response during…

Continue ReadingClinical outcomes in children with herpes simplex encephalitis receiving steroid therapy.

Frequency of the CCR5-delta32 allele in Brazilian populations: A systematic literature review and meta-analysis.

Abstract The CCR5 is a chemokine receptor widely expressed by several immune cells that are engaged in inflammatory responses. Some populations have individuals exhibiting a 32bp deletion in the CCR5…

Continue ReadingFrequency of the CCR5-delta32 allele in Brazilian populations: A systematic literature review and meta-analysis.
Read more about the article The molecular spectrum and distribution of haemoglobinopathies in Cyprus: a 20-year retrospective study.
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The molecular spectrum and distribution of haemoglobinopathies in Cyprus: a 20-year retrospective study.

Abstract Haemoglobinopathies are the most common monogenic diseases, posing a major public health challenge worldwide. Cyprus has one the highest prevalences of thalassaemia in the world and has been the…

Continue ReadingThe molecular spectrum and distribution of haemoglobinopathies in Cyprus: a 20-year retrospective study.