Read more about the article A computationally fast measure of epistasis for 2 SNPs and a categorical phenotype.
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A computationally fast measure of epistasis for 2 SNPs and a categorical phenotype.

Abstract Complex diseases may be caused by interactions or combined effects between multiple genetic and environmental factors. One of the main limitations of testing for interaction between genetic loci in…

Continue ReadingA computationally fast measure of epistasis for 2 SNPs and a categorical phenotype.
Read more about the article The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition.
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The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition.

Abstract hCINAP is an atypical nucleoplasmic enzyme, combining structural features of adenylate kinases and ATPases, which exhibits dual enzymatic activity. It interacts with the Cajal Body marker coilin and its…

Continue ReadingThe nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition.
Read more about the article Genetic differentiation of the house mouse around the Mediterranean basin: matrilineal footprints of early and late colonization.
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Genetic differentiation of the house mouse around the Mediterranean basin: matrilineal footprints of early and late colonization.

Abstract The molecular signatures of the recent expansion of the western house mouse, Mus musculus domesticus, around the Mediterranean basin are investigated through the study of mitochondrial D-loop polymorphism on…

Continue ReadingGenetic differentiation of the house mouse around the Mediterranean basin: matrilineal footprints of early and late colonization.
Read more about the article Cryptic diversity of free-living parabasalids, Pseudotrichomonas keilini and Lacusteria cypriaca n. g., n. sp., as inferred from small subunit rDNA sequences.
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Cryptic diversity of free-living parabasalids, Pseudotrichomonas keilini and Lacusteria cypriaca n. g., n. sp., as inferred from small subunit rDNA sequences.

Abstract Ultrastructural and molecular phylogenetic evidence indicate that the Parabasalia consists of seven main subgroups: the Trichomonadida, Honigbergiellida, Hypotrichomonadida, Tritrichomonadida, Cristamonadida, Spirotrichonymphida, and Trichonymphida. Only five species of free-living parabasalids…

Continue ReadingCryptic diversity of free-living parabasalids, Pseudotrichomonas keilini and Lacusteria cypriaca n. g., n. sp., as inferred from small subunit rDNA sequences.
Read more about the article A fast and efficient algorithm for mapping short sequences to a reference genome.
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A fast and efficient algorithm for mapping short sequences to a reference genome.

Abstract Novel high-throughput (Deep) sequencing technology methods have redefined the way genome sequencing is performed. They are able to produce tens of millions of short sequences (reads) in a single…

Continue ReadingA fast and efficient algorithm for mapping short sequences to a reference genome.
Read more about the article Molecular defects of the CYP21A2 gene in Greek-Cypriot patients with congenital adrenal hyperplasia.
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Molecular defects of the CYP21A2 gene in Greek-Cypriot patients with congenital adrenal hyperplasia.

Abstract To determine the mutations in the CYP21A2 gene in Greek-Cypriots with congenital adrenal hyperplasia (CAH) and attempt a genotype-phenotype correlation. Molecular analysis was performed by multiplex ligation-dependent probe amplification…

Continue ReadingMolecular defects of the CYP21A2 gene in Greek-Cypriot patients with congenital adrenal hyperplasia.
Read more about the article Cyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways.
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Cyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways.

Abstract Polycystic Kidney Disease is characterized by the formation of large fluid-filled cysts that eventually destroy the renal parenchyma leading to end-stage renal failure. Although remarkable progress has been made…

Continue ReadingCyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways.
Read more about the article Regulating complement in the kidney: insights from CFHR5 nephropathy.
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Regulating complement in the kidney: insights from CFHR5 nephropathy.

Abstract Complement factor H related protein 5 (CFHR5) nephropathy is a monogenic disorder of complement regulation that is endemic in Cyprus. The disease is characterised by haematuria, C3 glomerulonephritis and…

Continue ReadingRegulating complement in the kidney: insights from CFHR5 nephropathy.
Read more about the article Analysis of enterovirus and adenovirus presence in swimming pools in Cyprus from 2007-2008.
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Analysis of enterovirus and adenovirus presence in swimming pools in Cyprus from 2007-2008.

Abstract An analysis was carried out to determine the presence of enteroviruses and adenoviruses in public swimming pools in Cyprus. The effectiveness of the commonly implemented disinfection procedure of chlorination…

Continue ReadingAnalysis of enterovirus and adenovirus presence in swimming pools in Cyprus from 2007-2008.
Read more about the article Testing alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.
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Testing alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.

Abstract Geographic isolation in rainforest refugia and local adaptation to ecological gradients may both be important drivers of evolutionary diversification. However, their relative importance and the underlying mechanisms of these…

Continue ReadingTesting alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.