Read more about the article Genetic differentiation of the house mouse around the Mediterranean basin: matrilineal footprints of early and late colonization.
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Genetic differentiation of the house mouse around the Mediterranean basin: matrilineal footprints of early and late colonization.

Abstract The molecular signatures of the recent expansion of the western house mouse, Mus musculus domesticus, around the Mediterranean basin are investigated through the study of mitochondrial D-loop polymorphism on…

Continue ReadingGenetic differentiation of the house mouse around the Mediterranean basin: matrilineal footprints of early and late colonization.
Read more about the article Cryptic diversity of free-living parabasalids, Pseudotrichomonas keilini and Lacusteria cypriaca n. g., n. sp., as inferred from small subunit rDNA sequences.
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Cryptic diversity of free-living parabasalids, Pseudotrichomonas keilini and Lacusteria cypriaca n. g., n. sp., as inferred from small subunit rDNA sequences.

Abstract Ultrastructural and molecular phylogenetic evidence indicate that the Parabasalia consists of seven main subgroups: the Trichomonadida, Honigbergiellida, Hypotrichomonadida, Tritrichomonadida, Cristamonadida, Spirotrichonymphida, and Trichonymphida. Only five species of free-living parabasalids…

Continue ReadingCryptic diversity of free-living parabasalids, Pseudotrichomonas keilini and Lacusteria cypriaca n. g., n. sp., as inferred from small subunit rDNA sequences.
Read more about the article A fast and efficient algorithm for mapping short sequences to a reference genome.
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A fast and efficient algorithm for mapping short sequences to a reference genome.

Abstract Novel high-throughput (Deep) sequencing technology methods have redefined the way genome sequencing is performed. They are able to produce tens of millions of short sequences (reads) in a single…

Continue ReadingA fast and efficient algorithm for mapping short sequences to a reference genome.
Read more about the article Molecular defects of the CYP21A2 gene in Greek-Cypriot patients with congenital adrenal hyperplasia.
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Molecular defects of the CYP21A2 gene in Greek-Cypriot patients with congenital adrenal hyperplasia.

Abstract To determine the mutations in the CYP21A2 gene in Greek-Cypriots with congenital adrenal hyperplasia (CAH) and attempt a genotype-phenotype correlation. Molecular analysis was performed by multiplex ligation-dependent probe amplification…

Continue ReadingMolecular defects of the CYP21A2 gene in Greek-Cypriot patients with congenital adrenal hyperplasia.
Read more about the article Cyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways.
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Cyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways.

Abstract Polycystic Kidney Disease is characterized by the formation of large fluid-filled cysts that eventually destroy the renal parenchyma leading to end-stage renal failure. Although remarkable progress has been made…

Continue ReadingCyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways.
Read more about the article Hydrophilic cationic star homopolymers based on a novel diethanol-N-methylamine dimethacrylate cross-linker for siRNA transfection: synthesis, characterization, and evaluation.
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Hydrophilic cationic star homopolymers based on a novel diethanol-N-methylamine dimethacrylate cross-linker for siRNA transfection: synthesis, characterization, and evaluation.

Abstract Four cationic hydrophilic star homopolymers based on the novel hydrophilic, positively ionizable cross-linker bis(methacryloyloxyethyl)methylamine (BMEMA) were synthesized using sequential group transfer polymerization (GTP) and were, subsequently, evaluated for their…

Continue ReadingHydrophilic cationic star homopolymers based on a novel diethanol-N-methylamine dimethacrylate cross-linker for siRNA transfection: synthesis, characterization, and evaluation.
Read more about the article X-linked Alport syndrome in Hellenic families: phenotypic heterogeneity and mutations near interruptions of the collagen domain in COL4A5.
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X-linked Alport syndrome in Hellenic families: phenotypic heterogeneity and mutations near interruptions of the collagen domain in COL4A5.

Abstract The X-linked Alport syndrome (ATS) is caused by mutations in COL4A5 and exhibits a widely variable expression. Usually ATS is heralded with continuous microhematuria which rapidly progresses to proteinuria,…

Continue ReadingX-linked Alport syndrome in Hellenic families: phenotypic heterogeneity and mutations near interruptions of the collagen domain in COL4A5.
Read more about the article Testing alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.
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Testing alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.

Abstract Geographic isolation in rainforest refugia and local adaptation to ecological gradients may both be important drivers of evolutionary diversification. However, their relative importance and the underlying mechanisms of these…

Continue ReadingTesting alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.
Read more about the article Near-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.
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Near-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.

Abstract Near-full genome sequences are presented in this report for the first time of unclassified HCV strains amplified using RT-PCR from plasma of patients living in Cyprus. One strain appears…

Continue ReadingNear-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.
Read more about the article BioTextQuest: a web-based biomedical text mining suite for concept discovery.
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BioTextQuest: a web-based biomedical text mining suite for concept discovery.

Abstract BioTextQuest combines automated discovery of significant terms in article clusters with structured knowledge annotation, via Named Entity Recognition services, offering interactive user-friendly visualization. A tag-cloud-based illustration of terms labeling…

Continue ReadingBioTextQuest: a web-based biomedical text mining suite for concept discovery.