Read more about the article Near-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.
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Near-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.

Abstract Near-full genome sequences are presented in this report for the first time of unclassified HCV strains amplified using RT-PCR from plasma of patients living in Cyprus. One strain appears…

Continue ReadingNear-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.
Read more about the article BioTextQuest: a web-based biomedical text mining suite for concept discovery.
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BioTextQuest: a web-based biomedical text mining suite for concept discovery.

Abstract BioTextQuest combines automated discovery of significant terms in article clusters with structured knowledge annotation, via Named Entity Recognition services, offering interactive user-friendly visualization. A tag-cloud-based illustration of terms labeling…

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Read more about the article Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatin.
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Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatin.

Abstract The peptide compstatin and its derivatives inhibit the complement-component protein C3 in primate mammals and are potential therapeutic agents against the unregulated activation of complement in humans, but are…

Continue ReadingDesign of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatin.
Read more about the article Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery.
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Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery.

Abstract Emerging perioperative genomics may influence the direction of risk assessment and surgical strategies in cardiac surgery. The aim of this study was to investigate whether single nucleotide polymorphisms (SNP)…

Continue ReadingThrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery.
Read more about the article Split-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo.
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Split-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo.

Abstract Proteins labelled with Quantum Dots (QDs) can be imaged over long periods of time with ultrahigh spatial and temporal resolution, yielding important information on the spatiotemporal dynamics of proteins…

Continue ReadingSplit-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo.
Read more about the article Towards an extension of the two-variable model of carcinogenesis through oncogenes and tumour suppressor genes.
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Towards an extension of the two-variable model of carcinogenesis through oncogenes and tumour suppressor genes.

Abstract Currently, carcinogenesis is considered to be the result of mal-expression of tumour suppressor genes and oncogenes, leading either way to uncontrollable and disorganized cell mitosis. Recently a novel class…

Continue ReadingTowards an extension of the two-variable model of carcinogenesis through oncogenes and tumour suppressor genes.
Read more about the article A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies.
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A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies.

Abstract A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological-histological correlations. In…

Continue ReadingA correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies.
Read more about the article The role of molecular genetics in diagnosing familial hematuria(s).
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The role of molecular genetics in diagnosing familial hematuria(s).

Abstract Familial microscopic hematuria (MH) of glomerular origin represents a heterogeneous group of monogenic conditions involving several genes, some of which remain unknown. Recent advances have increased our understanding and…

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Read more about the article Genetic variation in Mediterranean Helichrysum italicum (Asteraceae; Gnaphalieae): do disjunct populations of subsp. microphyllum have a common origin?
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Genetic variation in Mediterranean Helichrysum italicum (Asteraceae; Gnaphalieae): do disjunct populations of subsp. microphyllum have a common origin?

Abstract The yellow-flowered everlasting daisy Helichrysum italicum (Asteraceae, Gnaphalieae) is widely distributed in the Mediterranean basin, where it grows in continuous and widespread populations in diverse open habitats. Helichrysum italicum…

Continue ReadingGenetic variation in Mediterranean Helichrysum italicum (Asteraceae; Gnaphalieae): do disjunct populations of subsp. microphyllum have a common origin?
Read more about the article Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle.
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Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle.

Abstract MicroRNAs (miRNAs) are small RNA molecules that post-transcriptionally regulate gene expression and have been shown to play an important role during development. miR-1, miR-133a, miR-133b and miR-206 are expressed…

Continue ReadingExpression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle.