Read more about the article Testing alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.
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Testing alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.

Abstract Geographic isolation in rainforest refugia and local adaptation to ecological gradients may both be important drivers of evolutionary diversification. However, their relative importance and the underlying mechanisms of these…

Continue ReadingTesting alternative hypotheses for evolutionary diversification in an African songbird: rainforest refugia versus ecological gradients.
Read more about the article Near-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.
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Near-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.

Abstract Near-full genome sequences are presented in this report for the first time of unclassified HCV strains amplified using RT-PCR from plasma of patients living in Cyprus. One strain appears…

Continue ReadingNear-full genome characterization of unclassified hepatitis C virus strains relating to genotypes 1 and 4.
Read more about the article BioTextQuest: a web-based biomedical text mining suite for concept discovery.
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BioTextQuest: a web-based biomedical text mining suite for concept discovery.

Abstract BioTextQuest combines automated discovery of significant terms in article clusters with structured knowledge annotation, via Named Entity Recognition services, offering interactive user-friendly visualization. A tag-cloud-based illustration of terms labeling…

Continue ReadingBioTextQuest: a web-based biomedical text mining suite for concept discovery.
Read more about the article The spectrum of mutations identified in Cypriot patients with phenylalanine hydroxylase deficiency detected through neonatal screening.
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The spectrum of mutations identified in Cypriot patients with phenylalanine hydroxylase deficiency detected through neonatal screening.

Abstract The purpose of this study was to identify the mutations responsible for phenylalanine hydroxylase deficiency in Cypriot patients detected through neonatal screening. Analysis of the PAH gene was performed…

Continue ReadingThe spectrum of mutations identified in Cypriot patients with phenylalanine hydroxylase deficiency detected through neonatal screening.
Read more about the article A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy.
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A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy.

Abstract Heparin binding epidermal growth factor (HBEGF) is expressed in podocytes and was shown to play a role in glomerular physiology. MicroRNA binding sites on the 3'UTR of HBEGF were…

Continue ReadingA miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy.
Read more about the article High-resolution whole-mount in situ hybridization using Quantum Dot nanocrystals.
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High-resolution whole-mount in situ hybridization using Quantum Dot nanocrystals.

Abstract The photostability and narrow emission spectra of nanometer-scale semiconductor crystallites (QDs) make them desirable candidates for whole-mount fluorescent in situ hybridization to detect mRNA transcripts in morphologically preserved intact…

Continue ReadingHigh-resolution whole-mount in situ hybridization using Quantum Dot nanocrystals.
Read more about the article The analysis of near full-length genome sequences of HIV type 1 subtype A viruses from Russia supports the monophyly of major intrasubtype clusters.
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The analysis of near full-length genome sequences of HIV type 1 subtype A viruses from Russia supports the monophyly of major intrasubtype clusters.

Abstract The HIV-1 epidemic in Russia has been insufficiently studied, with only 11 complete genome sequences from this country currently available, only three of which are of the locally predominant…

Continue ReadingThe analysis of near full-length genome sequences of HIV type 1 subtype A viruses from Russia supports the monophyly of major intrasubtype clusters.
Read more about the article Down-regulation of myogenin can reverse terminal muscle cell differentiation.
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Down-regulation of myogenin can reverse terminal muscle cell differentiation.

Abstract Certain higher vertebrates developed the ability to reverse muscle cell differentiation (dedifferentiation) as an additional mechanism to regenerate muscle. Mammals, on the other hand, show limited ability to reverse…

Continue ReadingDown-regulation of myogenin can reverse terminal muscle cell differentiation.
Read more about the article Evidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria.
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Evidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria.

Abstract Familial hematuria (FH) is associated with at least two pathological entities: thin basement membrane nephropathy (TBMN), caused by heterozygous COL4A3/COL4A4 mutations, and C3 nephropathy caused by CFHR5 mutations. It…

Continue ReadingEvidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria.
Read more about the article Conservation of endemic and threatened wildlife: molecular forensic DNA against poaching of the Cypriot mouflon (Ovis orientalis ophion, Bovidae).
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Conservation of endemic and threatened wildlife: molecular forensic DNA against poaching of the Cypriot mouflon (Ovis orientalis ophion, Bovidae).

Abstract Molecular DNA techniques in combination with appropriate reference population database and statistical methods are fundamental tools to forensic wildlife investigations. This is even more relevant when taxa with uncertain…

Continue ReadingConservation of endemic and threatened wildlife: molecular forensic DNA against poaching of the Cypriot mouflon (Ovis orientalis ophion, Bovidae).