Read more about the article Increased number of microRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction.
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Increased number of microRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction.

Abstract MicroRNAs (miRNAs) and copy number variations (CNVs) are two newly discovered genetic elements that have revolutionized the field of molecular biology and genetics. By performing in silico whole genome…

Continue ReadingIncreased number of microRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction.
Read more about the article Regulating complement in the kidney: insights from CFHR5 nephropathy.
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Regulating complement in the kidney: insights from CFHR5 nephropathy.

Abstract Complement factor H related protein 5 (CFHR5) nephropathy is a monogenic disorder of complement regulation that is endemic in Cyprus. The disease is characterised by haematuria, C3 glomerulonephritis and…

Continue ReadingRegulating complement in the kidney: insights from CFHR5 nephropathy.
Read more about the article Analysis of enterovirus and adenovirus presence in swimming pools in Cyprus from 2007-2008.
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Analysis of enterovirus and adenovirus presence in swimming pools in Cyprus from 2007-2008.

Abstract An analysis was carried out to determine the presence of enteroviruses and adenoviruses in public swimming pools in Cyprus. The effectiveness of the commonly implemented disinfection procedure of chlorination…

Continue ReadingAnalysis of enterovirus and adenovirus presence in swimming pools in Cyprus from 2007-2008.
Read more about the article The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study.
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The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study.

Abstract Diet has long been suspected to impact on breast cancer risk. In this study we evaluated whether the degree of adherence to a Mediterranean diet pattern modifies breast cancer…

Continue ReadingThe mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study.
Read more about the article Autoimmune channelopathies of the nervous system.
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Autoimmune channelopathies of the nervous system.

Abstract Ion channels are complex transmembrane proteins that orchestrate the electrical signals necessary for normal function of excitable tissues, including the central nervous system, peripheral nerve, and both skeletal and…

Continue ReadingAutoimmune channelopathies of the nervous system.
Read more about the article Multilocus microsatellite typing (MLMT) of strains from Turkey and Cyprus reveals a novel monophyletic L. donovani sensu lato group.
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Multilocus microsatellite typing (MLMT) of strains from Turkey and Cyprus reveals a novel monophyletic L. donovani sensu lato group.

Abstract New foci of human CL caused by strains of the Leishmania donovani (L. donovani) complex have been recently described in Cyprus and the Çukurova region in Turkey (L. infantum)…

Continue ReadingMultilocus microsatellite typing (MLMT) of strains from Turkey and Cyprus reveals a novel monophyletic L. donovani sensu lato group.
Read more about the article The spectrum of mutations identified in Cypriot patients with phenylalanine hydroxylase deficiency detected through neonatal screening.
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The spectrum of mutations identified in Cypriot patients with phenylalanine hydroxylase deficiency detected through neonatal screening.

Abstract The purpose of this study was to identify the mutations responsible for phenylalanine hydroxylase deficiency in Cypriot patients detected through neonatal screening. Analysis of the PAH gene was performed…

Continue ReadingThe spectrum of mutations identified in Cypriot patients with phenylalanine hydroxylase deficiency detected through neonatal screening.
Read more about the article A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy.
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A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy.

Abstract Heparin binding epidermal growth factor (HBEGF) is expressed in podocytes and was shown to play a role in glomerular physiology. MicroRNA binding sites on the 3'UTR of HBEGF were…

Continue ReadingA miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy.
Read more about the article High-resolution whole-mount in situ hybridization using Quantum Dot nanocrystals.
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High-resolution whole-mount in situ hybridization using Quantum Dot nanocrystals.

Abstract The photostability and narrow emission spectra of nanometer-scale semiconductor crystallites (QDs) make them desirable candidates for whole-mount fluorescent in situ hybridization to detect mRNA transcripts in morphologically preserved intact…

Continue ReadingHigh-resolution whole-mount in situ hybridization using Quantum Dot nanocrystals.
Read more about the article The analysis of near full-length genome sequences of HIV type 1 subtype A viruses from Russia supports the monophyly of major intrasubtype clusters.
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The analysis of near full-length genome sequences of HIV type 1 subtype A viruses from Russia supports the monophyly of major intrasubtype clusters.

Abstract The HIV-1 epidemic in Russia has been insufficiently studied, with only 11 complete genome sequences from this country currently available, only three of which are of the locally predominant…

Continue ReadingThe analysis of near full-length genome sequences of HIV type 1 subtype A viruses from Russia supports the monophyly of major intrasubtype clusters.