Read more about the article Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery.
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Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery.

Abstract Emerging perioperative genomics may influence the direction of risk assessment and surgical strategies in cardiac surgery. The aim of this study was to investigate whether single nucleotide polymorphisms (SNP)…

Continue ReadingThrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery.
Read more about the article Split-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo.
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Split-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo.

Abstract Proteins labelled with Quantum Dots (QDs) can be imaged over long periods of time with ultrahigh spatial and temporal resolution, yielding important information on the spatiotemporal dynamics of proteins…

Continue ReadingSplit-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo.
Read more about the article Towards an extension of the two-variable model of carcinogenesis through oncogenes and tumour suppressor genes.
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Towards an extension of the two-variable model of carcinogenesis through oncogenes and tumour suppressor genes.

Abstract Currently, carcinogenesis is considered to be the result of mal-expression of tumour suppressor genes and oncogenes, leading either way to uncontrollable and disorganized cell mitosis. Recently a novel class…

Continue ReadingTowards an extension of the two-variable model of carcinogenesis through oncogenes and tumour suppressor genes.
Read more about the article Down-regulation of myogenin can reverse terminal muscle cell differentiation.
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Down-regulation of myogenin can reverse terminal muscle cell differentiation.

Abstract Certain higher vertebrates developed the ability to reverse muscle cell differentiation (dedifferentiation) as an additional mechanism to regenerate muscle. Mammals, on the other hand, show limited ability to reverse…

Continue ReadingDown-regulation of myogenin can reverse terminal muscle cell differentiation.
Read more about the article Evidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria.
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Evidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria.

Abstract Familial hematuria (FH) is associated with at least two pathological entities: thin basement membrane nephropathy (TBMN), caused by heterozygous COL4A3/COL4A4 mutations, and C3 nephropathy caused by CFHR5 mutations. It…

Continue ReadingEvidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria.
Read more about the article Conservation of endemic and threatened wildlife: molecular forensic DNA against poaching of the Cypriot mouflon (Ovis orientalis ophion, Bovidae).
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Conservation of endemic and threatened wildlife: molecular forensic DNA against poaching of the Cypriot mouflon (Ovis orientalis ophion, Bovidae).

Abstract Molecular DNA techniques in combination with appropriate reference population database and statistical methods are fundamental tools to forensic wildlife investigations. This is even more relevant when taxa with uncertain…

Continue ReadingConservation of endemic and threatened wildlife: molecular forensic DNA against poaching of the Cypriot mouflon (Ovis orientalis ophion, Bovidae).
Read more about the article Acute promyelocytic leukemia: an experience on 95 greek patients treated in the all-trans-retinoic Acid era.
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Acute promyelocytic leukemia: an experience on 95 greek patients treated in the all-trans-retinoic Acid era.

Abstract Acute promyelocytic leukemia (APL) is highly curable with the combination of all-transretinoic acid (ATRA) and anthracycline based chemotherapy, but the percentage of early deaths remains high. In the present…

Continue ReadingAcute promyelocytic leukemia: an experience on 95 greek patients treated in the all-trans-retinoic Acid era.
Read more about the article A new public health genomics model for common complex diseases, with an application to common behavioral disorders.
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A new public health genomics model for common complex diseases, with an application to common behavioral disorders.

Abstract In the light of common forms of gene-environment interplay, particularly epigenomics and ecogenetics, the incorporation of envirome data into public health genomics models becomes necessary. Developing and restructuring public…

Continue ReadingA new public health genomics model for common complex diseases, with an application to common behavioral disorders.
Read more about the article LaTcOm: a web server for visualizing rare codon clusters in coding sequences.
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LaTcOm: a web server for visualizing rare codon clusters in coding sequences.

Abstract We present LaTcOm, a new web tool, which offers several alternative methods for 'rare codon cluster' (RCC) identification from a single and simple graphical user interface. In the current…

Continue ReadingLaTcOm: a web server for visualizing rare codon clusters in coding sequences.