Read more about the article Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes.
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Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes.

Abstract The insufficient ability of specialized cells such as neurons, cardiac myocytes, and epidermal cells to regenerate after tissue damage poses a great challenge to treat devastating injuries and ailments.…

Continue ReadingDirect conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes.
Read more about the article Differential expression of parental alleles of BRCA1 in human preimplantation embryos.
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Differential expression of parental alleles of BRCA1 in human preimplantation embryos.

Abstract Gene expression from both parental genomes is required for completion of embryogenesis. Differential methylation of each parental genome has been observed in mouse and human preimplantation embryos. It is…

Continue ReadingDifferential expression of parental alleles of BRCA1 in human preimplantation embryos.
Read more about the article KRAS and the Reality of Personalized Medicine in Non-small Cell Lung Cancer.
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KRAS and the Reality of Personalized Medicine in Non-small Cell Lung Cancer.

Abstract Lung cancer is the leading cause of mortality among all cancer types, worldwide. Latest available global statistics of World Health Organization report 1.59 million casualities in 2012 alone. Worldwide,…

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Read more about the article Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd.
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Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd.

Abstract Gene expression data are accumulating exponentially in public repositories. Reanalysis and integration of themed collections from these studies may provide new insights, but requires further human curation. Here we…

Continue ReadingExtraction and analysis of signatures from the Gene Expression Omnibus by the crowd.
Read more about the article Associations between social vulnerabilities and dietary patterns in European children: the Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS) study.
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Associations between social vulnerabilities and dietary patterns in European children: the Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS) study.

Abstract Socio-economic inequalities in childhood can determine dietary patterns, and therefore future health. This study aimed to explore associations between social vulnerabilities and dietary patterns assessed at two time points,…

Continue ReadingAssociations between social vulnerabilities and dietary patterns in European children: the Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS) study.
Read more about the article CSF tau correlates with the degree of cortical involvement in E200K familial Creutzfeldt-Jakob disease.
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CSF tau correlates with the degree of cortical involvement in E200K familial Creutzfeldt-Jakob disease.

Abstract Cerebrospinal fluid (CSF) tau was found to correlate with disease severity and cognitive status in E200K familial Creutzfeldt-Jakob disease (fCJD) patients. The objective of the present study was to…

Continue ReadingCSF tau correlates with the degree of cortical involvement in E200K familial Creutzfeldt-Jakob disease.
Read more about the article Assessing the potential of pharmaceuticals and their transformation products to cause mutagenic effects: Implications for gene expression profiling.
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Assessing the potential of pharmaceuticals and their transformation products to cause mutagenic effects: Implications for gene expression profiling.

Abstract The selection and prioritization of pharmaceuticals and their transformation products for evaluating effects on the environment and human health is a challenging task. One common approach is based on…

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Read more about the article Kisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells.
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Kisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells.

Abstract Uterine tissue was collected from bitches after ovariohysterectomy at different times after ovulation. Samples were assigned to four groups: metestrous non-pregnant, day 10-12, n = 4; pre-implantation, day 10-12, n = 9; post-implantation,…

Continue ReadingKisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells.
Read more about the article Associations between exclusive breastfeeding and physical fitness during childhood.
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Associations between exclusive breastfeeding and physical fitness during childhood.

Abstract Exposure to breastfeeding improves the survival, health, and development of children; therefore, breast milk is recommended as the exclusive nutrient source for feeding term infants during the first 6 months.…

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Read more about the article A synthesis of radial growth patterns preceding tree mortality.
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A synthesis of radial growth patterns preceding tree mortality.

Abstract Tree mortality is a key factor influencing forest functions and dynamics, but our understanding of the mechanisms leading to mortality and the associated changes in tree growth rates are…

Continue ReadingA synthesis of radial growth patterns preceding tree mortality.