Read more about the article Clinical radiological correlation in E200K familial Creutzfeldt-Jakob disease.
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Clinical radiological correlation in E200K familial Creutzfeldt-Jakob disease.

Abstract The use of diffusion MRI improved the accuracy of diagnosis in Creutzfeldt-Jakob disease (CJD) and expanded our knowledge of the changes occurring in the brain during the disease. The…

Continue ReadingClinical radiological correlation in E200K familial Creutzfeldt-Jakob disease.
Read more about the article Detection of a Yersinia pestis gene homologue in rodent samples.
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Detection of a Yersinia pestis gene homologue in rodent samples.

Abstract A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and…

Continue ReadingDetection of a Yersinia pestis gene homologue in rodent samples.
Read more about the article Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).
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Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).

Abstract Genome-wide association studies have found SNPs at 17q22 to be associated with breast cancer risk. To identify potential causal variants related to breast cancer risk, we performed a high…

Continue ReadingFine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).
Read more about the article Longitudinal associations of lifestyle factors and weight status with insulin resistance (HOMA-IR) in preadolescent children: the large prospective cohort study IDEFICS.
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Longitudinal associations of lifestyle factors and weight status with insulin resistance (HOMA-IR) in preadolescent children: the large prospective cohort study IDEFICS.

Abstract This study investigates prospective associations of anthropometrical and lifestyle indices with insulin resistance (IR) in European children from the IDEFICS cohort. Insulin resistance (IR) is a growing concern in…

Continue ReadingLongitudinal associations of lifestyle factors and weight status with insulin resistance (HOMA-IR) in preadolescent children: the large prospective cohort study IDEFICS.
Read more about the article Phylogeography of the Koala, (Phascolarctos cinereus), and Harmonising Data to Inform Conservation.
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Phylogeography of the Koala, (Phascolarctos cinereus), and Harmonising Data to Inform Conservation.

Abstract The Australian continent exhibits complex biogeographic patterns but studies of the impacts of Pleistocene climatic oscillation on the mesic environments of the Southern Hemisphere are limited. The koala (Phascolarctos…

Continue ReadingPhylogeography of the Koala, (Phascolarctos cinereus), and Harmonising Data to Inform Conservation.
Read more about the article Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
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Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.

Abstract The results of the study reported here are part of an ongoing integrated research programme aimed at producing additional, robust, evidence on the genetic resistance to classical scrapie in…

Continue ReadingGoats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
Read more about the article Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.
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Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.

Abstract P.I157T is a CHEK2 missense mutation associated with a modest increase in breast cancer risk. Previously, another CHEK2 mutation, the protein truncating c.1100delC has been associated with poor prognosis…

Continue ReadingPatient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.
Read more about the article Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.
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Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

Abstract CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk…

Continue ReadingGenetic modifiers of CHEK2*1100delC-associated breast cancer risk.
Read more about the article Sudden unexpected death in epilepsy: experience from a tertiary epilepsy centre in Cyprus with review of the literature.
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Sudden unexpected death in epilepsy: experience from a tertiary epilepsy centre in Cyprus with review of the literature.

Abstract Sudden unexpected death in epilepsy (SUDEP) affects 0.09-9.3 per 1,000 person-years depending on the population studied and constitutes the most common cause of death in people with epilepsy. The…

Continue ReadingSudden unexpected death in epilepsy: experience from a tertiary epilepsy centre in Cyprus with review of the literature.
Read more about the article Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.
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Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.

Abstract Changes in histone modifications are an attractive model through which environmental signals, such as diet, could be integrated in the cell for regulating its lifespan. However, evidence linking dietary…

Continue ReadingLoss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.