Read more about the article Mediterranean diet-gene interactions: A targeted metabolomics study in Greek-Cypriot women.
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Mediterranean diet-gene interactions: A targeted metabolomics study in Greek-Cypriot women.

Abstract A high adherence to the Mediterranean diet (MD) was previously associated with a decreased risk of breast cancer (BC) among Greek-Cypriot women. Additionally, particular polymorphisms were shown to modulate…

Continue ReadingMediterranean diet-gene interactions: A targeted metabolomics study in Greek-Cypriot women.
Read more about the article rs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk.
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rs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk.

Abstract NBS1, also known as NBN, plays an important role in maintaining genomic stability. Interestingly, rs2735383 G > C, located in a microRNA binding site in the 3'-untranslated region (UTR) of NBS1,…

Continue Readingrs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk.
Read more about the article Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions.
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Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions.

Abstract DNA methylation is an epigenetic marker that has been shown to vary significantly across different tissues. Taking advantage of the methylation differences between placenta-derived cell-free DNA and maternal blood,…

Continue ReadingWhole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions.
Read more about the article Plasma pentraxin-3 is associated with endothelial dysfunction in non-alcoholic fatty liver disease.
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Plasma pentraxin-3 is associated with endothelial dysfunction in non-alcoholic fatty liver disease.

Abstract Pentraxin-3 (PTX-3) is an acute-phase protein belonging to the PTX family. It has been reported that PTX-3 is significantly associated with obesity, metabolic syndrome, and cardiovascular diseases (CVD). Non-alcoholic…

Continue ReadingPlasma pentraxin-3 is associated with endothelial dysfunction in non-alcoholic fatty liver disease.
Read more about the article Glucosinolate biosynthesis in Eruca sativa.
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Glucosinolate biosynthesis in Eruca sativa.

Abstract Glucosinolates (GSLs) are a highly important group of secondary metabolites in the Caparalles order, both due to their significance in plant-biome interactions and to their chemoprotective properties. This study…

Continue ReadingGlucosinolate biosynthesis in Eruca sativa.
Read more about the article A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study.
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A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study.

Abstract The melanocortin-4 receptor gene (MC4R) plays a pivotal role in the regulation of body fat and food and energy intake. The objectives of the study were as follows: 1)…

Continue ReadingA Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study.
Read more about the article A novel COL4A1 frameshift mutation in familial kidney disease: the importance of the C-terminal NC1 domain of type IV collagen.
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A novel COL4A1 frameshift mutation in familial kidney disease: the importance of the C-terminal NC1 domain of type IV collagen.

Abstract Hereditary microscopic haematuria often segregates with mutations of COL4A3, COL4A4 or COL4A5 but in half of families a gene is not identified. We investigated a Cypriot family with autosomal…

Continue ReadingA novel COL4A1 frameshift mutation in familial kidney disease: the importance of the C-terminal NC1 domain of type IV collagen.
Read more about the article Associations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents – Results from the IDEFICS/I.Family Cohort.
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Associations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents – Results from the IDEFICS/I.Family Cohort.

Abstract Polyunsaturated n-3 and n-6 polyunsaturated fatty acids (PUFA) are precursors of biologically active metabolites that affect blood pressure (BP) regulation. This study investigated the association of n-3 and n-6…

Continue ReadingAssociations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents – Results from the IDEFICS/I.Family Cohort.
Read more about the article Quality of Life of Cypriot Patients Suffering with Huntington’s Disease.
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Quality of Life of Cypriot Patients Suffering with Huntington’s Disease.

Abstract Huntington's disease (HD) has profound motor, behavioural and cognitive symptoms. Despite the enormous burden of this disease on the quality of life (QoL) of patients and their families, there…

Continue ReadingQuality of Life of Cypriot Patients Suffering with Huntington’s Disease.
Read more about the article PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
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PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

Abstract Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the concentration of LDL cholesterol and the risk of coronary heart disease, but…

Continue ReadingPCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.