Read more about the article Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.
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Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.

Abstract Spinal ventral interneurons regulate the activity of motor neurons, thereby controlling motor activities. Interneurons arise during embryonic development from distinct progenitor domains distributed orderly along the dorso-ventral axis of…

Continue ReadingVsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.
Read more about the article Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae.
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Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae.

Abstract Transcriptome studies have revealed that many eukaryotic genomes are pervasively transcribed producing numerous long non-coding RNAs (lncRNAs). However, only a few lncRNAs have been ascribed a cellular role thus…

Continue ReadingFunctional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae.
Read more about the article SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes.
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SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes.

Abstract Genome-wide association studies (GWAS) of single nucleotide polymorphisms (SNPs) have been successful in identifying loci contributing genetic effects to a wide range of complex human diseases and quantitative traits.…

Continue ReadingSCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes.
Read more about the article Sexual dimorphisms in genetic loci linked to body fat distribution.
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Sexual dimorphisms in genetic loci linked to body fat distribution.

Abstract Obesity is a chronic condition associated with increased morbidity and mortality and is a risk factor for a number of other diseases including type 2 diabetes and cardiovascular disease.…

Continue ReadingSexual dimorphisms in genetic loci linked to body fat distribution.
Read more about the article Accurate Breakpoint Mapping in Apparently Balanced Translocation Families with Discordant Phenotypes Using Whole Genome Mate-Pair Sequencing.
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Accurate Breakpoint Mapping in Apparently Balanced Translocation Families with Discordant Phenotypes Using Whole Genome Mate-Pair Sequencing.

Abstract Familial apparently balanced translocations (ABTs) segregating with discordant phenotypes are extremely challenging for interpretation and counseling due to the scarcity of publications and lack of routine techniques for quick…

Continue ReadingAccurate Breakpoint Mapping in Apparently Balanced Translocation Families with Discordant Phenotypes Using Whole Genome Mate-Pair Sequencing.
Read more about the article Loss of Coupling Distinguishes GJB1 Mutations Associated with CNS Manifestations of CMT1X from Those Without CNS Manifestations.
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Loss of Coupling Distinguishes GJB1 Mutations Associated with CNS Manifestations of CMT1X from Those Without CNS Manifestations.

Abstract CMT1X, an X-linked inherited neuropathy, is caused by mutations in GJB1, which codes for Cx32, a gap junction protein expressed by Schwann cells and oligodendrocytes. Many GJB1 mutations cause…

Continue ReadingLoss of Coupling Distinguishes GJB1 Mutations Associated with CNS Manifestations of CMT1X from Those Without CNS Manifestations.
Read more about the article Type 2 Diabetes Susceptibility in the Greek-Cypriot Population: Replication of Associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 Polymorphisms.
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Type 2 Diabetes Susceptibility in the Greek-Cypriot Population: Replication of Associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 Polymorphisms.

Abstract Type 2 diabetes (T2D) has been the subject of numerous genetic studies in recent years which revealed associations of the disease with a large number of susceptibility loci. We…

Continue ReadingType 2 Diabetes Susceptibility in the Greek-Cypriot Population: Replication of Associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 Polymorphisms.
Read more about the article Plasticity vs Mutation. The role of microRNAs in human adaptation.
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Plasticity vs Mutation. The role of microRNAs in human adaptation.

Abstract The variability potential of a phenotype, on the background of the same genotype, is termed "phenotypic plasticity". This is considered by some scientists as a more important evolutionary procedure…

Continue ReadingPlasticity vs Mutation. The role of microRNAs in human adaptation.
Read more about the article Molecular diagnostics for detecting pyrethroid and abamectin resistance mutations in Tetranychus urticae.
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Molecular diagnostics for detecting pyrethroid and abamectin resistance mutations in Tetranychus urticae.

Abstract Avermectin and pyrethroid resistance mutations (the G314D and the G326E in the glutamate gated chloride channels, and the F1538I in the voltage gated sodium channel) have been reported in…

Continue ReadingMolecular diagnostics for detecting pyrethroid and abamectin resistance mutations in Tetranychus urticae.
Read more about the article ITS2-rDNA Sequence Variation of s.l. (Dip: Psychodidae) Populations in Iran.
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ITS2-rDNA Sequence Variation of s.l. (Dip: Psychodidae) Populations in Iran.

Abstract s.l. is considered the most likely vector of in Iran. Although two morphotypes- (A) and (B)-have been formally described, further morphological and a molecular analysis of mitochondrial cytochrome oxidase…

Continue ReadingITS2-rDNA Sequence Variation of s.l. (Dip: Psychodidae) Populations in Iran.