Read more about the article Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
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Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.

Abstract The results of the study reported here are part of an ongoing integrated research programme aimed at producing additional, robust, evidence on the genetic resistance to classical scrapie in…

Continue ReadingGoats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
Read more about the article Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.
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Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.

Abstract P.I157T is a CHEK2 missense mutation associated with a modest increase in breast cancer risk. Previously, another CHEK2 mutation, the protein truncating c.1100delC has been associated with poor prognosis…

Continue ReadingPatient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.
Read more about the article Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.
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Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

Abstract CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk…

Continue ReadingGenetic modifiers of CHEK2*1100delC-associated breast cancer risk.
Read more about the article Quality of Life of Cypriot Patients Suffering with Huntington’s Disease.
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Quality of Life of Cypriot Patients Suffering with Huntington’s Disease.

Abstract Huntington's disease (HD) has profound motor, behavioural and cognitive symptoms. Despite the enormous burden of this disease on the quality of life (QoL) of patients and their families, there…

Continue ReadingQuality of Life of Cypriot Patients Suffering with Huntington’s Disease.
Read more about the article Associations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents – Results from the IDEFICS/I.Family Cohort.
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Associations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents – Results from the IDEFICS/I.Family Cohort.

Abstract Polyunsaturated n-3 and n-6 polyunsaturated fatty acids (PUFA) are precursors of biologically active metabolites that affect blood pressure (BP) regulation. This study investigated the association of n-3 and n-6…

Continue ReadingAssociations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents – Results from the IDEFICS/I.Family Cohort.
Read more about the article PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
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PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

Abstract Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the concentration of LDL cholesterol and the risk of coronary heart disease, but…

Continue ReadingPCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
Read more about the article Y-chromosomal haplogroup distribution in the Tuzla Canton of Bosnia and Herzegovina: A concordance study using four different in silico assignment algorithms based on Y-STR data.
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Y-chromosomal haplogroup distribution in the Tuzla Canton of Bosnia and Herzegovina: A concordance study using four different in silico assignment algorithms based on Y-STR data.

Abstract Y-chromosomal haplogroups are sets of ancestrally related paternal lineages, traditionally assigned by the use of Y-chromosomal single nucleotide polymorphism (Y-SNP) markers. An increasingly popular and a less labor-intensive alternative…

Continue ReadingY-chromosomal haplogroup distribution in the Tuzla Canton of Bosnia and Herzegovina: A concordance study using four different in silico assignment algorithms based on Y-STR data.
Read more about the article Regulation of On-Tree Vitamin E Biosynthesis in Olive Fruit during Successive Growing Years: The Impact of Fruit Development and Environmental Cues.
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Regulation of On-Tree Vitamin E Biosynthesis in Olive Fruit during Successive Growing Years: The Impact of Fruit Development and Environmental Cues.

Abstract The term vitamin E refers to a group of eight lipophilic compounds known as tocochromanols. The tocochromanols are divided into two groups, that is, tocopherols and tocotrienols, with four…

Continue ReadingRegulation of On-Tree Vitamin E Biosynthesis in Olive Fruit during Successive Growing Years: The Impact of Fruit Development and Environmental Cues.
Read more about the article Potential selection effects when estimating associations between the infancy peak or adiposity rebound and later body mass index in children.
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Potential selection effects when estimating associations between the infancy peak or adiposity rebound and later body mass index in children.

Abstract This study aims to evaluate a potential selection effect caused by exclusion of children with non-identifiable infancy peak (IP) and adiposity rebound (AR) when estimating associations between age and…

Continue ReadingPotential selection effects when estimating associations between the infancy peak or adiposity rebound and later body mass index in children.
Read more about the article Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells.
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Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells.

Abstract We previously identified focal adhesion kinase (FAK) as an important regulator of ciliogenesis in multiciliated cells. FAK and other focal adhesion (FA) proteins associate with the basal bodies and…

Continue ReadingAddressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells.