Read more about the article Association of desaturase activity and C-reactive protein in European children.
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Association of desaturase activity and C-reactive protein in European children.

Abstract Desaturase enzymes influence the fatty acid (FA) composition of body tissues and their activity affects the conversion rate of saturated to monounsaturated FA and of polyunsaturated FA (PUFA) to…

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Read more about the article Unsupervised data-driven stratification of mentalizing heterogeneity in autism.
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Unsupervised data-driven stratification of mentalizing heterogeneity in autism.

Abstract Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous. Novel approaches are needed to parse this heterogeneity to enhance precision in clinical and translational research. Applying a clustering…

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Read more about the article Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
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Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.

Abstract The results of the study reported here are part of an ongoing integrated research programme aimed at producing additional, robust, evidence on the genetic resistance to classical scrapie in…

Continue ReadingGoats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
Read more about the article Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.
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Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.

Abstract P.I157T is a CHEK2 missense mutation associated with a modest increase in breast cancer risk. Previously, another CHEK2 mutation, the protein truncating c.1100delC has been associated with poor prognosis…

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Read more about the article Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.
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Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

Abstract CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk…

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Read more about the article Sudden unexpected death in epilepsy: experience from a tertiary epilepsy centre in Cyprus with review of the literature.
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Sudden unexpected death in epilepsy: experience from a tertiary epilepsy centre in Cyprus with review of the literature.

Abstract Sudden unexpected death in epilepsy (SUDEP) affects 0.09-9.3 per 1,000 person-years depending on the population studied and constitutes the most common cause of death in people with epilepsy. The…

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Read more about the article Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.
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Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.

Abstract Changes in histone modifications are an attractive model through which environmental signals, such as diet, could be integrated in the cell for regulating its lifespan. However, evidence linking dietary…

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Read more about the article Functional assessment for elimination of mismatches in nuclear and whole cell extracts obtained from mouse and human blastocysts.
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Functional assessment for elimination of mismatches in nuclear and whole cell extracts obtained from mouse and human blastocysts.

Abstract Preimplantation embryos may have an increased risk of having mismatches due to the rates of cell proliferation and DNA replication. Elimination of mismatches in human gametes and embryos has…

Continue ReadingFunctional assessment for elimination of mismatches in nuclear and whole cell extracts obtained from mouse and human blastocysts.
Read more about the article On the brain structure heterogeneity of autism: Parsing out acquisition site effects with significance-weighted principal component analysis.
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On the brain structure heterogeneity of autism: Parsing out acquisition site effects with significance-weighted principal component analysis.

Abstract Neuroimaging studies have reported structural and physiological differences that could help understand the causes and development of Autism Spectrum Disorder (ASD). Many of them rely on multisite designs, with…

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Read more about the article Psychopathic personality traits in 5 year old twins: the importance of genetic and shared environmental influences.
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Psychopathic personality traits in 5 year old twins: the importance of genetic and shared environmental influences.

Abstract There is limited research on the genetic and environmental bases of psychopathic personality traits in children. In this study, psychopathic personality traits were assessed in a total of 1189…

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